Serotonin transporter knockout mice

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Persico AM, Baldi A, Dell Acqua ML, Moessner R, Murphy DL, Lesch KP, Keller F (2003) Reduced programmed cell death in brains of serotonin transporter knockout mice. Neuroreport 14 341-344... 

Sora 1, Wichems C, Takahashi N, Li XF, Zeng Z, Revay R, Lesch KP, Murphy D L, Uhl GR (1998) Cocaine reward models conditioned place preference can be established in dopamine-and in serotonin-transporter knockout mice. Proc Natl Acad Sci U S A 95 7699-7704... 

Wisor JP, Wurts SW, Hall FS, Lesch KP, Murphy DL, Uhl GR, Edgar DM (2003) Altered rapid eye movement sleep timing in serotonin transporter knockout mice. Neuroreport 14 233-238... 

Sora, Ichiro, Christine Wichems, Noboyuki Takahashi, Xiao-Fei Li, Zhizhen Zeng, Randal Revay, Klaus-Peter Lesch, Dennis L. Murphy, and George R. Uhl. 1998- "Cocaine Reward Models Conditioned Place Preference can be Established in Dopamine- and in Serotonin-Transporter Knockout Mice." Proceedings of the National Academy of Sciences of the United States of America 95 7699-7704. 

Ren-Patterson RF, Cochran FW, Holmes A, Sherrill S, Huang SJ, Tolliver T, Fesch KP, Fu B, Murphy DF. Foss of brain-derived neurotrophic factor gene allele exacerbates brain monoamine deficiencies and increases stress abnormalities of serotonin transporter knockout mice. J. Neurosci. Res. 2005 79 756-771. 

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Adamec R, Burton P, Blundell J, et al. Vulnerability to mild predator stress in serotonin transporter knockout mice. Behav Brain Res 2006 170(l) 126-40. 

Hybridization of Affymetrix Mu6500 GenChip using biotinylated cRNA probes synthesized from brain cDNAs of dopamine (DAT) and serotonin (SET) transporter gene knockout mice or double (DAT/SET) knockout mice is shown in Fig. 3. A gene transcript is represented by matches of 11-16 oligomers. The hybridization intensities of the perfect matches from separate knockout mouse brains are compared as shown. 

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