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Chitosan cartilage

Keywords Chitosan Nanoparticles Microspheres Chemically modified chitosans Polyelectrolyte complexes Oral and nasal administration Nerve, cartilage and bone regeneration Wound dressing... [Pg.152]

Chitosan freeze-dried fleeces support chondrocyte attachment and synthesis of extracellular matrix [344]. Chitosan was used to assist the spontaneous tissue repair of the meniscus [345]. The repair of the cartilage and the prevention of its degradation in osteoarthritis is, however, possible with the association of glucosamine sulfate salt and chondroitine sulfate, the latter being particularly effective [346]. [Pg.198]

While chitosan may not be a major player in the battle of the bulge, it may be of some use in the battle against osteoarthritis. This painful condition arises when the rubbery tissue found at the ends of bones, known as cartilage, begins to wear... [Pg.44]

Suh, J.K.F. Matthew, H.W.T. Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering A review. Biomaterials 2000, 21, 2589-2598. [Pg.2038]

Subramanian A et al (2004) Synthesis and evaluation of scaffolds prepared from chitosan fibers for potential use in cartilage tissue engineering. Biomed Sci Instrum 40 117-122... [Pg.211]

Subramanian A et al (2005) Preparation and evaluation of the electrospun chitosan/PEO fibers for potential applications in cartilage tissue engineering. J Biomater Sci Polym Ed 16(7) 861-873... [Pg.211]

Park et al. [102] designed an injectable cell delivery chitosan-Pluronic hydrogel for articular cartilage regeneration. The chitosan-Pluronic solution underwent a sol-gel transition at around 25 °C. The chitosan-Pluronic hydrogel showed effective chondrocyte proliferation and promoted extracellular matrix expression compared with alginate hydrogel. [Pg.36]

Tan HP, Chu CR et al (2009) Injectable in situ forming biodegradable chitosan-hyaluronic acid based hydrogels for cartilage tissue engineering. Biomaterials 30 2499-2506... [Pg.42]

Park KM, Lee SY et al (2009) Thermosensitive chitosan-pluronic hydrogel as an injectable cell dehvery carrier for cartilage regeneration. Acta Biomater 5 1956—1965... [Pg.42]

Chitosan scaffolds may find application in regeneration of skin tissue, liver tissue, bone and cartilage tissue, cardiac tissue, corneal tissue, and vascular tissue to mention a few [73]. A brief account of its application in various branches of tissue engineering is described in this section. [Pg.54]

Poly(L-lactide) (PLLA) microspheres using chitosan on the surface Bioactivity study on control PLLA and the chitosan-coated PLLA microspheres by in vitro culture Rabbit chondrocytes Larger amount of chitosan-coated PLLA microspheres exhibited enhanced cell attachment and proliferation Chitosan-coated PLLA microspheres may serve as injectable cell microcarriers for chondrogenesis in cartilage tissue Lao et al. [105]... [Pg.61]

Malafaya PB, Pedro AJ, Peterbauer A et al (2005) Chitosan particles agglomerated scaffolds for cartilage and osteochondral tissue engineering approaches with adipose tissue derived stem cells. J Mater Sci Mater Medicine 16 1077-1085... [Pg.72]

Muzzarelli RAA (2009) Chitins and chitosans for the repair of wounded skin, nerve, cartilage and bone. Carbohydr Polym 76 167-182... [Pg.76]

Yan LP, Wang YJ, Wu G et al (2010) Genipin-cross-linked collagen/chitosan biomimetic scaffolds for articular cartilage tissue engineering applications. J Biomed Mater Res 95A 465 75... [Pg.76]

Yamane S, Iwasaki N, Majima T et al (2005) Eeasibility of chitosan-based hyaluronic acid hybrid biomaterial for a novel scaffold in cartilage tissue engineering. Biomaterials 26 611-619... [Pg.77]

Chen YL, Lee HP, Chan HY et al (2007) Composite chondroitin-6-sulfate/dermatan sulphate/ chitosan scaffolds for cartilage tissue engineering. Biomaterials 28 2294—2305... [Pg.77]

Lao L, Tan H, Wang Y et al (2008) Chitosan modified poly(l-lactide) microspheres as cell microcarriers for cartilage tissue engineering. Colloids Surf B Biointerfaces 66 218-225... [Pg.77]

Tan H, Wu J, Lao L (2009) Gelatin/chitosan/hyaluronan scaffold integrated with PLGA microspheres for cartilage tissue engineering. Acta Biomater 5 328-337... [Pg.77]

This review firstly focuses on modification of the chitosan molecule to obtain desired properties and functions. The most important material forms (porous scaffolds, hydrogels, and rods) and delivery vectors fabricated from chitosan and its derivatives will be introduced. Particularly, the interaction and modulation of stem cell behavior by chitosan will be discussed. Finally, the applications of chitosan-based materials for repair and regeneration of various tissues and organs such as skin, cartilage, and bone will be summarized. [Pg.84]

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See also in sourсe #XX -- [ Pg.103 ]



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