Chitosan scaffolds

Human osteoblast-like MG63 cells were cultured on the macroporous chitosan scaffolds reinforced with hydroxyapatite or calcium phosphate invert glass were fabricated using a thermally induced phase separation technique. [Pg.171]

Chitosan scaffolds were reinforced with beta-tricalciiun phosphate and calcium phosphate invert glass [177]. Along the same line, composites of Loligo beta-chitin with octacalcium phosphate or hydroxyapatite were prepared by precipitation of the mineral into a chitin scaffold by means of a double diffusion system. The octacalciiun phosphate crystals with the usual form of 001 blades grew inside chitin layers preferentially oriented with the 100 faces parallel to the surface of the squid pen and were more stable to hy-... [Pg.173]

Madihally, S. V. and Matthew, W. T. (1999). Porous chitosan scaffolds for tissue engineering. Biomaterials 20,1133-1142. [Pg.118]

Altman et al. utilized a composite silk fibroin/chitosan scaffold for seeding and in vivo delivery of human ADSCs in a murine cutaneous wound model, and the delivery technique conferred physiological benefits to accelerated wound closure. ADSC seeded on a silk fibroin/chitosan scaffold differentiated into fibrovascular, endothelial, and epithelial components of restored tissue and enhanced the wound healing process [219]. [Pg.52]

VandeVord PJ, Matthew HWT et i (2002) Evaluation of the biocompatibility of a chitosan scaffold in mice. J Biomed Mater Res 59 585-590... [Pg.38]

Chitosan scaffolds may find application in regeneration of skin tissue, liver tissue, bone and cartilage tissue, cardiac tissue, corneal tissue, and vascular tissue to mention a few [73]. A brief account of its application in various branches of tissue engineering is described in this section. [Pg.54]

Collagen/chitosan porous Morphology, the swelling Human dermal fibroblasts The collagen/chitosan scaffolds can AU the in vitro and in vivo Ma et al. [Pg.56]

Chitosan crosslinked with dimethyl 3-3, dithio bis (propionimidate) (CS-DTBP) or glutaraldehyde (CS-GA) Cytotoxicity test Human dermal fibroblast cells in the presence of leachate from different chitosan scaffolds (chitosan, CS-GA and CS-DTBP) The number of cells that grew in the leachate from the CS-DTBP sample was significantly higher than the number of cells in the leachate from the CS-GA sample DTBP-crosslinked chitosan is less toxic than CS-GA scaffolds Adekogbe and Ghanem [80]... [Pg.56]

HA incorporated into chitosan scaffold by an in situ method... [Pg.59]

MC3T3-E1 cells on apatite-coated chitosan-nano-HA scaffolds showed better proliferation than on apatite-coated chitosan scaffolds... [Pg.59]

PDLLA)/chitosan scaffolds measured using MTT assay seeded onto the PDLLA/chitosan scaffolds scaffolds increased on increasing the weight ratio of the chitosan component, were able to preserve the phenotype of chondrocytes, and also supported the production of type II collagen scaffolds are able to promote the attachment and proliferation of chondrocytes [104]... [Pg.61]

Table 4 Application of chitosan scaffolds to liver tissue engineering... [Pg.63]

Porous chitosan scaffolds were Chitosan poured into a mold was The lower cell seeding A scaffold thickness of 200 pm Blan et al. [Pg.66]

Human venous fibroblasts onto the HLC/chitosan scaffolds. In vivo, scaffolds were implanted into rabbit liver... [Pg.67]

Wang AJ, Cao WL, Gong K et al (2006) Controlling morphology and porosity of 3-D chitosan scaffolds produced by thermally induced phase separation technique. Asian Chitin J 2 69-78... [Pg.73]

Rinki K, Dutta PK (2008) Preparation of genipin crosslinked chitosan scaffolds using supercritical carbon dioxide (sc. CO2). Asian Chitin J 4 43 8... [Pg.74]

Wei X, Wang K, Chen J (2011) The functional inorganic composites. Prog Chem 23 42-52 Rinki K, Shipra T, Dutta PK et al (2009) Direct chitosan scaffold formation via chitin whiskers by a supercritical carbon dioxide method a green approach. J Mater Chem 19 8651-8655... [Pg.74]

Rinki K, Dutta PK (2010) Physicochemical and biological activity study of genipin-cross-linked chitosan scaffolds prepared by using supercritical carbon dioxide for tissue engineering applications. Int J Biol Macromol 46 261-266... [Pg.74]

Li J, Pan J, Zhang L, Yu Y (2003) Culture of hepatocytes on fructose-modified chitosan scaffolds. Biomaterials 24 2317-2322... [Pg.75]

Adekogbe I, Ghanem A (2005) Fabrication and characterization of DTBP-crosslinked chitosan scaffolds for skin tissue engineering. Biomaterials 26 7241-7250 Liu FI, Fan FI, Cui Y et al (2007) Effects of the controlled-released basic fibroblast growth factor from chitosan-gelatin microspheres on a chitosan-gelatin scaffold. Biomacromolecules 8 1446-1455... [Pg.76]

Martins AM, Alves CM, Kasper FK et al (2010) Responsive and in ri/n-forming chitosan scaffolds for bone tissue engineering applications an overview of the last decade. J Mater Chem 20 1638-1645... [Pg.76]

Xu HHK, Simon CG Jr (2005) Fast setting calcium phosphate-chitosan scaffold mechanical properties and biocompatibility. Biomaterials 26 1337-1348... [Pg.76]

Kuo Y, Lin C (2006) Effect of genipin-crosslinked chitin-chitosan scaffolds with hydroxyapatite modifications on the cultivation of bovine knee chondrocytes. Biotechnol Bioeng 95 132-144... [Pg.76]

Manjubala I, Ponomarev I, Wilke I et al (2008) Growth of osteoblast-like cells on biomimetic apatite-coated chitosan scaffolds. J Biomed Mater Res Appl Biomater 84B 7-16... [Pg.76]

Sendemir-Urkmez A, Jamison RD (2006) The addition of biphasic calcium phosphate to porous chitosan scaffolds enhances bone tissue development in vitro. J Biomed Mater Res 81A 624-633... [Pg.76]

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