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Chitosan-Pluronic hydrogels

Park et al. [102] designed an injectable cell delivery chitosan-Pluronic hydrogel for articular cartilage regeneration. The chitosan-Pluronic solution underwent a sol-gel transition at around 25 °C. The chitosan-Pluronic hydrogel showed effective chondrocyte proliferation and promoted extracellular matrix expression compared with alginate hydrogel. [Pg.36]

Park KM, Lee SY et al (2009) Thermosensitive chitosan-pluronic hydrogel as an injectable cell dehvery carrier for cartilage regeneration. Acta Biomater 5 1956—1965... [Pg.42]

With the purpose of conferring thermosensitivity to chitosan-based hydrogels. Park et al. proposed the grafting of carboxylic acid-terminated poly(ethylene oxide-h-propylene oxide) block copolymer (Pluronic) onto the primary amine of chitosan, mediated by EDC coupling agent [102]. With the same purpose, Wang et al. grafted poly(N-isopropyl acrylamide) (NiPAM) chains onto chitosan by the copolymerization of acrylic acid-derivatized chitosan and N-isopropylacrylamide (NIPAAm) in aqueous solution [103]. [Pg.28]

In addition to PEG-based chitosan composites, temperature-sensitive chitosan composites have also been developed for tissue engineering applications by grafting of pluronics onto chitosan. This composite material formed a thermosensitive hydrogel that exhibited a transition temperature of 30-35°C when the grafting percentage was altered (Chung et al, 2005b). These thermosensitive... [Pg.163]

H.S. Yoo, Photo-cross-hnkable and thermo-responsive hydrogels containing chitosan and Pluronic for sustained release of human growth hormone (hGH), Journal of Biomaterials Science, Polymer Ed., 18 (11), 1429-1441,2007. [Pg.123]

Hybrid hydrogels based on chitosan and Pluronics have also shown thermo-responsive properties and exhibited superior hemostatic properties (Chung et al, 2005). Microfluidics were used by Wei et al (2011) to prepare pH-responsive microcapsules based on PDMAEMA. The cationic microcapsules obtained exhibited pH-sensitivity, and the preparation conditions significantly affected their pH-responsive swelling. [Pg.259]

Choi JS, Yoo HS (2010) Pluronic/chitosan hydrogels containing epidermal growth factor with wound-adhesive and photo-crosslinkable properties. J Biomed Mater Res A 95A 564—573... [Pg.228]

See other pages where Chitosan-Pluronic hydrogels is mentioned: [Pg.177]    [Pg.252]    [Pg.294]    [Pg.62]    [Pg.323]    [Pg.177]    [Pg.252]    [Pg.294]    [Pg.62]    [Pg.323]    [Pg.115]    [Pg.163]    [Pg.164]    [Pg.92]    [Pg.113]    [Pg.114]    [Pg.114]    [Pg.114]    [Pg.258]    [Pg.308]    [Pg.142]    [Pg.8]   
See also in sourсe #XX -- [ Pg.36 , Pg.115 ]



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Chitosan hydrogels

Chitosans hydrogels

Pluronic

Pluronic chitosan

Pluronics

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