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Thymic carcinoma

CK7 (-I-) adenocarcinomas of breast, lung, ovary, endometrium, and pancreas mesothelioma, urothelial carcinomas, thymic carcinomas and fibrolamellar variant of hepatocellular carcinomas. [Pg.217]

CD57 (leu 7) Neuroendocrine tumors T-cell lymphoma and pre T-ALL, chordoma, MPNST, germ cell tumors, papillary thyroid carcinoma, thymic carcinoma, germ cell tumors, synovial sarcoma, carcinoid tumors, schwannoma, mesothelioma, astrocytoma and glioblastoma NK-cells, Schwann cells, gastric chief cells, adrenal medulla, pancreatic islets, renal tubular epithelium, epithelial cells of thymic cortex, retina, oligodendrocytes... [Pg.61]

CML, mast cell disease, renal oncocytoma, renal chromophobe carcinoma, thymic carcinoma, seminoma, gliomas... [Pg.63]

J,l/mouse, twice a week for 25 weeks, to female ICR mice produced forestomach tumors (squamous cell carcinoma and papilloma), lung tumors (adenocarcinoma and adenoma), and tumors of the hematopoietic system (thymic lymphosarcoma and lymphatic leukemia), with dose-related response by 18 months. It was concluded that the target organ of benzotrichloride carcinogenesis in mice is the local tissue that is primarily exposed and the lung and hematopoietic tissue when administered systemically. [Pg.78]

Kastrup O, Meyring S, Diener HC. Atypical paraneoplastic brainstem encephalitis associated with anti-ri-antibodies due to thymic carcinoma with possible clinical response to immunoglobulins. Eur Neurol 2001 45(4) 285-287. [Pg.175]

Positive in the majority of thymic carcinomas of most histologic types... [Pg.237]

Tumors that may be confused with CUPS within the mediastinum include thymic neoplasm (thymoma, thymic carcinoid, or thymic carcinoma), thyroid tumors, lymphomas, paragangliomas, and germ cell tumors. Thymomas are generally easy to recognize owing to their characteristic admixture of neoplastic thymic epithelial cells with non-neoplastic lymphocytes. The neoplastic thymic epithelial cells are positive for keratins,... [Pg.238]

Berezowski K, Grimes MM, Gal A, Kornstein MJ. CD5 immunoreactivity of epithelial cells in thymic carcinoma and CASTLE using paraffin-embedded tissue. Am J Clin Pathol. 1996 106 483-486. [Pg.254]

Dorfman DM, Shahsafaei A, Chan JK. Thymic carcinomas, but not thymomas and carcinomas of other sites, show CDS immu-noreactivity. Am J Surg Pathol. 1997 21 936-940. [Pg.255]

Kornstein MJ, Rosai J. CDS labeling of thymic carcinomas and other nonlymphoid neoplasms. J ClinPathol. 1998 109 722-726. [Pg.255]

Tateyama H, Eimoto T, Tada T, et al. Immunoreactivity of a new CDS antibody with normal epithelium and malignant tumors including thymic carcinoma. Am J Clin Pathol. 1999 111 235-240. [Pg.255]

Kuo TT, Chan JK. Thymic carcinoma arising in thymoma is associated with alterations in immunohistochemical profile. Am J Surg Pathol. 1998 22 1474-1481. [Pg.255]

Suster S, Moran CA. Spindle cell thymic carcinoma clinico-pathologic and immunohistochemical study of a distinctive variant of primary thymic epithelial neoplasm. Am J Surg Pathol. 1999 23 691-700. [Pg.255]

Truong LD, Mody DR, Cagle PT, et al. Thymic carcinoma. A clinicopathologic study of 13 cases. Am J Surg Pathol. 1990 14 151-166. [Pg.255]

Thymic NE tumors include carcinoids, atypical carcinoids, and small cell carcinomas. Morphologically, individual tumors often show admixtures of these growth... [Pg.329]

Moran CA, Suster S. Thymic NE carcinomas with combined features ranging from well-differentiated (carcinoid) to small cell carcinoma A clinicopathologic and immunohistochemical study of 11 cases. Am J Clin Pathol. 2000 113 345-350. [Pg.339]

De Montpreville VT, Macchiarini P, Dulmet E. Thymic NE carcinoma (carcinoid) A clinicopathologic study of fourteen cases. Thorac Cardiovasc Surg. 1996 111 134-141. [Pg.339]

Hishima T, Fukayama M, Hayashi Y, et al. NE differentiation in thymic epithelial tumors with special reference to thymic carcinoma and atypical thymoma. Hum Pathol. 1998 29 330-338. [Pg.339]

Basaloid squamous cell carcinoma (BSCC) also may be either a primary thymic tumor > ° or a mediastinal metastasis from a primary neoplasm of the oropharynx, hypopharynx, larynx, esophagus, lungs, or anorectal region. Keratin is universally present in BSCC with a diffuse cytoplasmic pattern of labeling, and reactivity for epithelial membrane antigen, keratin 5/6, and p63 may also be observed. h78,80,8i author s experi-... [Pg.346]

Several reports have been made on the expression of CD5 by the epithelial cells of thymic carcinoma, but there are no reports on conventional thymoma available (Fig. 11.19).112-114,120 statement must be... [Pg.352]

Some variability exists in the literature concerning mutant pS3 protein as another potential discriminant between thymoma and thymic carcinoma.In general, however, immunostains performed with the DOl and D03 antibodies against mutant pS3 are much more likely to yield positive results in PTC than in conventional thymoma. Hence, this determinant could serve as an adjunct in making the diagnostic distinction between those two entities. Similar claims have been made for... [Pg.352]

Parathyroid carcinoma (PAC) may be seen intrathymically or in the soft tissue of the anterosuperior mediastinum. It bears a considerable resemblance to thymic neuroendocrine carcinoma in some cases, and paraganglioma also enters into differential diagnosis.The clinical diagnosis of malignant parathyroid lesions is typically... [Pg.353]

FIGURE 11.19 Diffuse immunoreactivity for CDS in primary thymic carcinoma. [Pg.353]

FIGURE 11.20 Occult labeling for synaptophysin (S) (A) in a primary thymic carcinoma that did not have neuroendocrine characteristics by conventional morphologic study (B). [Pg.354]

FIGURE 11.23 Diffuse positivity for CD30 in thymic embryonai carcinoma. [Pg.355]

As stated earlier in this discussion, most non-hema-topoietic malignancies of the mediastinum should be presumed metastatic until proven otherwise. Immunohistologic analysis is only variably productive in establishing a site of origin for secondary carcinomas in this location. If determinants are found that are unassociated with PTCs, such as TTF-1, thyroglobulin, prostate-specific antigen, S-100 protein, FLAP, CA 19-9 (an enteric carcinoma marker), or CA 125 (a serosal and Mullerian tract marker),it is likely that the lesion is a metastasis. Conversely, the presence of coexpression of keratin 5/6, p63, and CD5 would, at least tentatively, appear to support a thymic origin for such a neoplasm. [Pg.357]

Comparatively few examples of sarcomatoid thymic carcinoma (STC) have been reported. 499-201 Microscopically, this lesion is characterized by fascicles of fusiform and pleomorphic tumor cells, with little internal organization. Some cases, however, contain limited foci in which cohesive epithelioid cell nests are admixed with... [Pg.359]

Fukai I, Masaoka A, Hashimoto T, et al. Differential diagnosis of thymic carcinoma and lung carcinoma with the use of antibodies to cytokeratins./ Thorac Cardiovasc Surg. 1995 110 1670-1675. [Pg.364]

Walker AN, Mills SE, Fechner RE. Thymomas and thymic carcinomas. Semin Diagn Pathol. 1990 7 250-265. [Pg.364]

Shimizu J, Hayashi Y, Morita K, et al. Primary thymic carcinoma A clinicopathological and immunohistochemical study. J Surg Oncol. 1994 56 159-164. [Pg.365]

Suster S, Rosai J. Thymic carcinoma A clinicopathologic study of 60 cases. Cancer. 1991 67 1025-1032. [Pg.365]

Snover DC, Levine GD, Rosai J. Thymic carcinomas Five distinctive histological variants. Am J Surg Pathol. 1982 6 451-470. [Pg.365]

See other pages where Thymic carcinoma is mentioned: [Pg.462]    [Pg.121]    [Pg.2529]    [Pg.217]    [Pg.237]    [Pg.237]    [Pg.238]    [Pg.254]    [Pg.293]    [Pg.343]    [Pg.350]    [Pg.350]    [Pg.351]    [Pg.352]    [Pg.353]    [Pg.353]    [Pg.359]    [Pg.365]   
See also in sourсe #XX -- [ Pg.350 , Pg.351 , Pg.352 ]



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