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Papillary thyroid carcinoma

Lahr G, Sticha M, Schtitzea K, et al. Diagnosis of papillary thyroid carcinoma is facilitated by using an RT-PCR approach on laser-microdissected archival material to detect RET oncogene activation. Pathobiology 2000 68 218-226. [Pg.69]

Radioactive iodine is indicated in hyperthyroidism due to Graves disease or toxic nodular goitre and also used as palliative therapy after thyroidectomy for papillary carcinoma of thyroid. [Pg.295]

He H, Jazdzewski K, Li W et al. The role of microRNA genes in papillary thyroid carcinoma. Proc Natl Acad Sci USA 2005 102 19075-19080. [Pg.55]

CS is a 27-year-old woman who recently underwent a total thyroidectomy for papillary thyroid carcinoma and is now hypothyroid. Which of the following is the best therapy for hypothyroidism ... [Pg.60]

Mazzaferri EL, Robbins Rj, Spencer CA, Braverman LE, Pacini F, et al. A consensus report of the role of serum thyroglobulm as a monitoring method for low-risk patients with papillary thyroid carcinoma. Clin Endocrinol Metab 2003 88 1433-41,... [Pg.2095]

Rowe LR, Bentz BG, Bentz JS. Detection of BRAF V600E activating mutation in papillary thyroid carcinoma using PCR with allele-specific fluorescent probe melting curve analysis. J Clin Pathol. 2007 60 1211-1215. [Pg.56]

Kimura ET, Nikiforova MN, Zhu Z, et al. High prevalence of BRAE mutations in thyroid cancer genetic evidence for constitutive activation of the RET/PTC-RAS-BRAE signaling pathway in papillary thyroid carcinoma. Cancer Res. 2003 63 1454-1457. [Pg.56]

Nikiforova MN, Caudill CM, Biddinger P, et al. Prevalence of RET/PTC rearrangements in Hashimoto s thyroiditis and papillary thyroid carcinomas. Int J Surg Pathol. 2002 10 15-22. [Pg.57]

ELST is most often confused with metastatic papillary thyroid carcinoma (PTC) and chorioid plexus papilloma (GPP). PTC is positive for thyroglobulin, whereas ELST is not. CPPs are positive for transthyretin and GEAP the ELST is usually negative for both of these markers. ... [Pg.281]

FIGURE 10.8 Papillary thyroid carcinoma. The cells in this well-differentiated tumor reveal uniform reactivity for thyroglobulin. (Immunoperoxidase stain for thyroglobulin.)... [Pg.299]

FIGURE 10.10 Papillary thyroid carcinoma. Immunoperoxidase stain for CKl 9 demonstrates intense cytoplasmic reactivity. [Pg.301]

Numerous other proteins have been explored as potential markers for different types of thyroid malignancies (Table 10.3). Cbp/p300-interacting transactivator 1 (CITEDl) is a nuclear protein that is involved in the coregulation of transcription factors. This protein is present in a variety of different cell types and is overexpressed in papillary thyroid carcinomas (87% to 93%). However, CITEDl immunoreactivity is also expressed in up to 50% of follicular carcinomas, 16% of follicular adenomas, and 24% of nodular goiters. [Pg.303]

FIGURE 10.16 Beta-catenin stain of papillary thyroid carcinoma. The tumor cells exhibit prominent staining of their plasma membranes and moderate cytoplasmic positivity. Intranuclear pseudoinclusions are positively stained (arrows). [Pg.304]

FIGURE 10.17 A, Papillary thyroid carcinoma, oncocytic type (H E stain). B, Immunoperoxidase stain for mitochondria using the antibody MITO-11 3 demonstrates intense granular cytoplasmic staining. [Pg.305]

Keen CE, Szakacs S, Okon E, et al. CA125 and thyroglobulin staining in papillary carcinomas of thyroid and ovarian origin is not entirely specific for site of origin. Histopathology. 1999 34 113-117. [Pg.331]

Schelfhout LJDM, van Muijen GN, Fleuren GJ. Expression of keratin 19 distinguishes papillary thyroid carcinoma from follicular carcinomas and follicular thyroid adenoma. Am J Clin Pathol. 1989 92 654-658. [Pg.332]

Kragsterman B, Grimelius L, Wallin G, et al. Cytokeratin 19 expression in papillary thyroid carcinoma. Appl Immunohisto-chem. 1999 7 181-185. [Pg.332]

Tallin G, Santoro M, Helie M, et al. RET/PTC oncogene activation defines a subset of papillary thyroid carcinomas lacking evidence of progression to poorly differentiated or undifferentiated tumor phenotypes. Clin Cancer Res. 1998 4 287-294. [Pg.332]

Casey MB, Lohse CM, Lloyd RV. Distinction between papillary thyroid hyperplasia and papillary thyroid carcinoma by immunohistochemical staining for cytokeratin 19, galectin-3 and HBME-1. Endocr Pathol. 2003 14 55-60. [Pg.332]

Cheung CC, Ezzat S, Freeman JL, et al. Immunohistochemi-cal diagnosis of papillary thyroid carcinoma. Mod Pathol. 2001 14 338-342. [Pg.332]

Prasad ML, Pellegata NS, Kloos RT, et al. CITEDl expression suggests papillary thyroid carcinoma in high throughput tissue microarray-based study. Thyroid. 2004 14 169-175. [Pg.332]

Huang Y, Prasad M, Lemon WJ, et al. Gene expression in papillary thyroid carcinoma reveals highly consistent profiles. Proc Nat l Acad Sci USA. 2001 98 15044-15049. [Pg.332]

Sconamiglio T, Hyjek E, Kao J, et al. Diagnostic usefulness of HBME-1, galectin-3, CK19 and CITEDl and evaluation of their expression in encapsulated lesions with questionable featrrres of papillary thyroid carcinoma. Am J Clin Pathol. 2006 126 700-708. [Pg.332]

Alves P, Soares P, Fonseca E, Sohrinho-Simoes M. Papillary thyroid carcinoma overexpresses fully and underglycosylated mucins togethet with native and sialylated simple mucin antigens and histo-blood group antigens. Endocrine Pathol. 1999 10 315-324. [Pg.333]

Zhu Z, Gandhi M, Nikiforova MN, et al. Molecular profile and clinical-pathological features of the follicular variant of papillary thyroid carcinoma. An unusually high prevalence of ras mutations. Am J Clin Pathol. 2003 120 71-77. [Pg.334]

Giordano TJ, Kuick R, Thomas DG, et al. Molecular classification of papillary thyroid carcinoma distinct BRAF, RAS, RET/ PTC mutations-specific gene expression profiles discovered by DNA microarray analysis. Oncogene. 2005 24 6646-6656. [Pg.334]

Castellone M. D., Guarino V., De Falco V., et al. (2004) Functional expression of the CXCR4 chemokine receptor is induced by RET/PTC oncogenes and is a common event in human papillary thyroid carcinomas. Oncogene, 23, 5958-67. [Pg.40]

See other pages where Papillary thyroid carcinoma is mentioned: [Pg.29]    [Pg.236]    [Pg.352]    [Pg.293]    [Pg.281]    [Pg.33]    [Pg.783]    [Pg.2059]    [Pg.293]    [Pg.293]    [Pg.299]    [Pg.299]    [Pg.303]    [Pg.310]    [Pg.554]    [Pg.31]    [Pg.151]   
See also in sourсe #XX -- [ Pg.299 , Pg.301 , Pg.303 , Pg.305 , Pg.309 ]



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