Carcinoma basaloid squamous cell

Basaloid squamous cell carcinoma (BSCC) is an uncommon, histologically distinct variant of SCC. In the upper aerodigestive tract, it occurs frequently in the base of the tongue, tonsils, hypopharynx, and larynx but has also been described in many other locations such as the palate, buccal mucosa, floor of mouth, nasopharynx, nasal cavity, and trachea. This is one of the subtypes of squamous carcinoma that can present with large neck node metastases and an unknown primary tumor. [Pg.258]

TABLE 9.2 Differentiating Basaloid Squamous Cell Carcinoma from Adenoid Cystic and Small Cell Neuroendocrine Carcinoma ... [Pg.259]

The differential diagnosis for basaloid squamous cell carcinoma (BSCC) includes adenoid cystic carcinoma and small cell neuroendocrine carcinoma. [Pg.260]

Paulino AF, Singh B, Shah JP, et al. Basaloid squamous cell carcinoma of the head and neck. Laryngoscope. 2000 110(9) 1479-1482. [Pg.284]

Morice WG, Ferreiro JA. Distinction of basaloid squamous cell carcinoma from adenoid cystic and small cell undifferentiated carcinoma by immunohistochemistry. Human Pathol. 1998 29 609-612. [Pg.285]

Tsubochi H, Suzuki T, Suzuki S, et al. Immunohistochemical study of basaloid squamous cell carcinoma, adenoid cystic and mucoepidermoid carcinoma in the upper aerodigestive tract. Anticancer Research. 2000 20(2B) 1205-1211. [Pg.285]

Emanuel P, Wang B, Wu M, et al. p63 Immunohistochemistry in the distinction of adenoid cystic carcinoma from basaloid squamous cell carcinoma. Mod Pathol. 2005 18(5) 645-650. [Pg.285]

Basaloid squamous cell carcinoma (BSCC) also may be either a primary thymic tumor > ° or a mediastinal metastasis from a primary neoplasm of the oropharynx, hypopharynx, larynx, esophagus, lungs, or anorectal region. Keratin is universally present in BSCC with a diffuse cytoplasmic pattern of labeling, and reactivity for epithelial membrane antigen, keratin 5/6, and p63 may also be observed. h78,80,8i author s experi-... [Pg.346]

FIGURE 14.5 Differential staining patterns of basaloid-patterned esophageal carcinomas. ACC, adenoid cystic carcinoma BSCC, basaloid squamous cell carcinoma HG NEC, high-grade neuroendocrine carcinoma. [Pg.504]

Central areas or nests of basaloid squamous cell carcinoma are CK5/6 and p63 positive, whereas the peripheral rim of palisading cells may be CK19 positive. [Pg.504]

Most adenoid cystic-like carcinomas are basaloid squamous cell carcinomas. True adenoid cystic carcinomas of the esophagus are extremely rare. [Pg.504]

Kawahata K, Makimoto K, Maekawa T, et al. An immunohistochemical examination of basaloid squamous cell carcinoma of the esophagus report of a case. Surg Today. 2001 31 655-659. [Pg.532]

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