BIOSIS database

The main pre-clinical species used for pharmacokinetic studies are the rat, mouse and dog. An examination of the Biosys database for 2000 and 2001 shows that of the abstracted papers, 6334 mapped to the subject heading Pharmacokinetics . Of these, the vast majority (70%) were studies on humans. Studies on rats constituted 14% of the reports, mice 7.5% and dogs 3.4% (Table 6.2). Nonhuman primates can also be important pharmacokinetic models, but ethical and practical considerations severely limit studies in these animals such that, within the same period, they represented less than 0.5% of the abstracted reports on PK. 

The Scientific World at http //www.thescientihcworld.com/ offers literature searching through SciBase, a collection of databases of scientific, technical, and medical research literature. SciBase currently covers more than 19 million documents published since 1965 in more than 30,000 journals. SciBase content is derived from databases created by the National Library of Medicine (MEDLINE), the British Library, BIOSIS, and PASCAL, as well as CAB ABSTRACTS. Abstracts are sometimes available free and individual articles are available for purchase. 

ChemBioBase Suite (Jubilant Biosys) Target-centric ligand databases 1.4 Mio Journals and patents Yes... 

Research articles of interest to biochemists may appear in many types of research journals. Research libraries do not have the funds necessary to subscribe to every journal, nor do scientists have the time to survey every current journal copy for articles of interest. Two publications that help scientists to keep up with published articles are Chemical Titles (published every 2 weeks by the American Chemical Society) and the weekly Current Contents available in hard copy and computer disks (published by the Institute of Science Information). The Life Science edition of Current Contents is the most useful for biochemists. The computer revolution has reached into the chemical and biochemical literature, and most college and university libraries now subscribe to computer bibliographic search services. One such service is STN International, the scientific and technical information network. This on-line system allows direct access to some of the world s largest scientific databases. The STN databases of most value to life scientists include BIOSIS Pre-views/RN (produced by Bio Sciences Information Service covers original research reports, reviews, and U.S. patents in biology and biomedicine), CA (produced by Chemical Abstracts service covers research reports in all areas of chemistry), MEDLINE, and MEDLARS (produced by the U.S. National Library of Medicine and Index Medicus, respectively cover all areas of biomedicine). These networks provide on-line service and their databases can be accessed from personal computers in the office, laboratory, or library. Some... 

II. Product Summary Jubilant Biosys has created some content products in the bioinformatics and chemoinformatics area. These products leverage Jubilant s curation services to incorporate extensive curated databases with structured query modules and front-ends for data retrieval. The content is for the drug discovery process, specifically in the areas of target prioritization and lead identification. The databases are available in Oracle, SD format, and ISIS/Base DB formats and can be exported. The database can be queried across text, structure, substructure and sequences with built-in query modules. Some of the key parameters on which information is curated are ... 

Contains more than 14 million citations to the worldwide literature in the life sciences, environmental sciences, and experimental medicine dating back to 1969. One of the largest of the science databases. Produced by BIOSIS. Selected citations contained in a subset of TOXLINE. (Data-Star, CISTI, DIALOG, DIMDI, OVID, STN)... 

Most of the major biomedical literature databases utilize specific indexing terms to reference pharmacokinetic and pharmacodynamic information. MEDLINE introduced the term pharmacokinetics in 1988 as both a medical subject heading and subheading. Pharmacokinetics and pharmacodynamics are both EMTREE vocabulary terms and are used as subheadings in BIOSIS . 

BIOSIS Previews . 1969-. Philadelphia, PA BIOSIS. Weekly. This database is a combination of Biological Abstracts and Biological Ahstracts/Reports, Reviews, Meetings, with information from more than 5500 sources worldwide. Over 560,000 new citations are added each year. Available online. 

We searched for publications of the years 2000 to May 2007 that included ecological population models for pesticide risk assessment. First, the databases BIOSIS, CAB Abstracts, and PASCAL were searched for papers, including a combination of the following keywords in title, abstract, or keywords (risk assessment) AND (simulation OR model ) AND (population OR ecologS) AND (crop protection product OR pesticide OR insecticide OR fungicide OR herbicide). 

The search of the BIOSIS, CAB Abstracts, and PASCAL databases yielded 444 publications. After scanning titles and abstracts, 73 publications were identified as potentially relevant for our review. We cross-checked these publications with our own databases, and found that our filters did not detect all relevant publications, for example, Stark et al. (2004). We included 19 additional publications from our own databases, ending up with 92 publications. After the detailed evaluation of these publications, 39 publications were selected for our quantitative assessment of the state of the art. One of these publications, Bartell et al. (2003), contained 3 different models, adding up to a number of 41 models evaluated in our review. Overall, we believe that our sample should be representative, although we certainly were not able to detect all publications of the years 2000 to May 2007 that are relevant for our review. 

In addition to their inclusion in the CAS databases, CAS Registry Numbers are used in many public and private databases. Currently, the cluster of databases on STN International containing Registry Numbers includes 7 CAS databases and 53 non-CAS databases. Among the latter are such diverse files as AIDSLINE, BIOSIS, Design Institute for Physical Property Data File (DIPPR), MEDLINE, Natural Products Alert (NAPRALERT), Pharmaceutical News Index (PNI), and Plastics Materials Selection Database (PLASPEC). 

BIOSIS, which covers all aspects of biological sciences, includes chemistry and medicine CANCERLIT, CANCERPROJ and CANCERPROT are databases giving information on cancer and related topics... 

Chinese researchers did their best in nanoelectrochemistry, resulting in the vastest number of published papers in the world. When setting nano and electrochem as topics, we have surveyed the statistical data from the database of Web of Science, BIOSIS previews, Derwent Innovations Index, MEDLINE, and Journal of Citation Reports for the period from U Jan, 2001 to 2U December, 2012. The results are illustrated in Fig. 2. The world s top 10 countries/regions that published the largest number of papers on nanoelectrochemistry are illustrated in Fig. 2a. Among the total 59480... 

STN Easy is a service introduced on the World A de Web in 1996. It provides point-and-click Web access to certain scientific/technical STN international databases such as REGISTRY, CAPLUS, BIOSIS, INSPEC, and MEDLINE. There is a wide range of scientific subject categories, basic or more advanced searching and an ability to refine your search strategies and set preferences are included. 3D structures can... 

Producer BIOSIS, USA Bretherick s Reactive Chemical Hazards Database ... 

It is possible to access several databases at the same time (multifile searching) FIL CA,BIOSIS,MEDLINE,EMBASE... 

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