BIOSIS

BIOSIS BIOSIS (USA) Biological Abstracts biosdences/ biomedical biblio. 13mio journals, patent offices, proceed- ings. books STN online weekly www.hiosis.OTg... 

BIOSIS, [Internet]. URL http //www.biosis.org/ home deluxe.html, accessed 9-17-2000. 

The main pre-clinical species used for pharmacokinetic studies are the rat, mouse and dog. An examination of the Biosys database for 2000 and 2001 shows that of the abstracted papers, 6334 mapped to the subject heading Pharmacokinetics . Of these, the vast majority (70%) were studies on humans. Studies on rats constituted 14% of the reports, mice 7.5% and dogs 3.4% (Table 6.2). Nonhuman primates can also be important pharmacokinetic models, but ethical and practical considerations severely limit studies in these animals such that, within the same period, they represented less than 0.5% of the abstracted reports on PK. 

Tab. 6.2. Numbers of pharmacokinetic studies by animal. Numbers of papers abstracted into Biosys Previews and mapping to the Subject Heading Pharmacokinetics.

The Scientific World at http //www.thescientihcworld.com/ offers literature searching through SciBase, a collection of databases of scientific, technical, and medical research literature. SciBase currently covers more than 19 million documents published since 1965 in more than 30,000 journals. SciBase content is derived from databases created by the National Library of Medicine (MEDLINE), the British Library, BIOSIS, and PASCAL, as well as CAB ABSTRACTS. Abstracts are sometimes available free and individual articles are available for purchase. 

Scarascia-Mugnozza G, Schettini E, Vox G (2004) Effects of solar radiation on the radiometric properties of biodegradable films for agricultural applications. Biosys Eng 87 479 187. doi 10.1016/j.biosystemseng.2004.01.008... 

ChemBioBase Suite (Jubilant Biosys) Target-centric ligand databases 1.4 Mio Journals and patents Yes... 

Research articles of interest to biochemists may appear in many types of research journals. Research libraries do not have the funds necessary to subscribe to every journal, nor do scientists have the time to survey every current journal copy for articles of interest. Two publications that help scientists to keep up with published articles are Chemical Titles (published every 2 weeks by the American Chemical Society) and the weekly Current Contents available in hard copy and computer disks (published by the Institute of Science Information). The Life Science edition of Current Contents is the most useful for biochemists. The computer revolution has reached into the chemical and biochemical literature, and most college and university libraries now subscribe to computer bibliographic search services. One such service is STN International, the scientific and technical information network. This on-line system allows direct access to some of the world s largest scientific databases. The STN databases of most value to life scientists include BIOSIS Pre-views/RN (produced by Bio Sciences Information Service covers original research reports, reviews, and U.S. patents in biology and biomedicine), CA (produced by Chemical Abstracts service covers research reports in all areas of chemistry), MEDLINE, and MEDLARS (produced by the U.S. National Library of Medicine and Index Medicus, respectively cover all areas of biomedicine). These networks provide on-line service and their databases can be accessed from personal computers in the office, laboratory, or library. Some... 

BIOSIS Previews Bio sis BRS, Dialog, ESA-IRS, Data-Star, Orbit, STN life sciences... 

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