Base safety

J. A. Wilkinson and B. W. Balls, "Microprocessor-Based Safety Systems Designed for Fine and Gas and Emergency Shutdown AppHcations,"... 

Zhu, T. L. 1993 A Reliability Based Safety Factor for Aircraft Composite Structures. Computers and Structures, 48(4), 745-748. 

To broaden your input, you might ask others in your company (for example, divisional or facility-based safety professionals) to conduct the same review—... 

Some effective team structures distinguish between a core group and a standing advisory group. This can be helpful in assuring consistent feedback from key people (such as facility-based safety experts) who may be unable to participate in regular working sessions but whose input and endorsement will be critical to success. 

Marcombe, J. T., Krause, T. R., Finley, R. M. (1993). Behavior Based Safety at Monsanto s Pensacola plant. The Chemical Engineer, April 29. 

The investigation of minor groove-binding polyamides was greatly accelerated by the implementation of solid-phase synthesis [48]. Originally demonstrated on Boc-y9-Ala-PAM resin with Boc-protected monomers, it was also shown that Fmoc chemistry could be employed with suitably protected monomers and Fmoc-y9-Ala-Wang resin (Fig. 3.8) [49]. Recently, Pessi and coworkers used a sulfonamide-based safety-catch resin to prepare derivatives of hairpin polyamides [50]. Upon activation of the linker, resin-bound polyamides were readily cleaved with stoichiometric quantities of nucleophile to provide thioesters or peptide conjugates. 

MIR based SLM Maturity Index on Reliability based Safety Lifecycle Management... 

Many companies have implemented a system to have peers observe and try to correct the behavior of peers by coaching or other means. This is part of a behavior based safety management system. This system should operate in the nonincident portion of the error pyramid. Include examples in a listing, such as Table 5-1, to illustrate the differences. 

Application of a nonscientifically based safety factor to take into account political aspects, socioeconomic aspects (cost-benefit considerations), or risk perception factors (the nature of the effect may justify the use of an additional factor). 

Resin-bound amides generally need to be activated to make them susceptible to saponification under acceptably mild reaction conditions [114] (Table 3.5). Particularly elegant are those linkers that allow this activation to be realized as the final synthetic step before cleavage (safety-catch linkers [115-117]). The activation of some amide-based safety-catch linkers is outlined in Figure 3.9. 

Figure 3.9. Activation and nucleophilic cleavage of amide-based safety-catch linkers [118,119].

K. Thomas et al., Research strategies for safety evaluation of nanomaterials, Part VIII International efforts to develop risk-based safety evaluations for nanomaterials. Toxicol. Sci. 92, 23-32 (2006)... 

Problems to be solved Objects State of the input data base Safety assurance Physical protection SNF unioading SNF management Dismantiem ent Management of toxic v este Management of RW Environment ai rehabiiitation Priority... 

The political decision to build and take into use a deep geological repository for long term storage of spent nuclear fuel will largely depend on the outcome of thorough scientifically-based safety assessments. Given the very long operational time span for the repository, the... 

Another powerful sulfur-based safety-catch linker was developed by Kahne et foj- the... 

The strategies described in Schemes 4.6.S-4.6.9 thus combine efficiently a novel sulfur-based safety-catch linker strategy, multigeneration construction of thio-linked pyrimidines with a multidirectional cleavage procedure. This approach should prove successful for the solid-phase synthesis of a whole range of nitrogen-containing heterocycles such as pyrimidines, triazines, imidazoles, benzimidazoles. 

DePasquale, J. P., Geller, E. S. (1999). Critical success factors for behavior-based safety A smdy of twenty industry wide appUcations. Journal of Safety Research, 30(4), 237-249. 

Penny 1, Eaton A, Bishop P, Bloomfield R. The practicalities of goal-based safety. Proceedings of the Ninth Safety-Critical Systems Symposium Bristol, UK, 6-8 Feb 2001. Springer, 2001 ISBN 1-85233-411-8 2001. p. 35-48. 

Menon C, Hawkins R, McDermid J. Defence Standard 00-56 Issue 4 towards evidence-based safety standards. Safety-critical systems problems, process and practice. York, UK 2009. p. 223-43. 

Frederick, J. and Lessin, N. (2000) Blame the worker - the rise of behavioural based safety programmes. Multinational Monitor, 21(11), 10-17. 

John Austin 2006. An introduction to behavior-based safety. Stone, Sand Gravel Review (2) 38-39. 

This paper aimed to find the regularity of the direct cause of gas explosion, through the study of analysis of the generic unsafe act in the coalmine major gas explosion accidents based on the behavior based safety model, the following conclusions can be drawn ... 

Fu Gui, et al. 2013. Discussions on theoretical understanding and effects of behavior based safety, China Safety Science Journal, 23(3) 150-154. 

The direct cause of the accident is unsafe acts. Therefore, preventing unsafe acts of employees and making them to complete the task by safe acts is particularly important. Mentioning unsafe behavior study and solutions BBS (Behavior-Based Safety) is mainly used abroad (LI Nai-wen JI Da-jiang 2011). The application of BBS method requires a longer time to build a safety culture... 

LI Nai-wen, JI Da-jiang. Application Study on Behavior-based Safety in Coal Mine Behavior Management. China Safety Science Journal 2011 (12) 115 121. 

Terry E. McSween. 2011. The values-based safety process improving your safety. Beijing Electronics industry Press. 

Out of all kinds of methods of preventing accident, BBS (Behavior Based Safety) plays a significant role in the control and improvement of personal behavior, but the time it works lasts too long. BBS cannot satisfy the need of Chinese safety production, as far as the characteristic of instantaneity of accident occurrence and Chinese accident-prone situation are concerned. In fact, BBS is seldom used in Chinese coal mine in order to prevent accident and improve safety. 

Nonetheless, if one assumes that all pyrrole-containing drugs are toxic, we would have missed atorvastatin (Lipitor). Atorvastatin is remarkably safe barring the mechanism-based safety concerns such as rhabdomyolysis that are associated with all HMG-CoA inhibitors. Although atorvastatin contains the pyrrole ring, it has at least three factors that strongly attenuate its nucleophilicity. First, it is fully substituted at all... 

Schneider Electric has been designing and manufacturing I C solutions dedicated to the implementation of safety and safety related functions in nuclear power plants for more than 25 years. The first solutions were non software-based. Since 1980, software-based safety solutions have been successfully developed and used. 

---