Critical success factors

Cooper, R. G. and Kleinschmidt, E. J. 1995 Benchmarking the Finu s Critical Success Factors in New Product Development. Journal of Product Innovation Management, 12(5), 374-391. 

HTS matured from an art to a science and with this evolution the need to attract, train, and retain a diverse scientific staff became a critical success factor for leaders of every HTS organization. The modem HTS organizations present a unique... 

Before starting an improvement process, a clear picture of the supply chain has to be obtained. Therefore, Supply Chain Analysis is a critical success factor. Usually, this analysis will describe the as-is status and the desired to-be status. As a supply chain is built up of different companies for a limited time, it is essential that all partners speak the same language to describe and measure the as-is-status as well as to evaluate the to-be-status. For this purpose, usually a widely accepted model called the SCOR-model is used. 

These were issues that were predominantly mentioned in time-period 2, but not time-period 1. These are actions characterizing the second period of the study but not the first, or critical success factors relevant at the later stages of change. A frequency difference of three or more would represent predominance for a sample of this size. 

To summarise, while there is always considerable uncertainty in ED and no decision wiU be infallible, the risk of selecting the wrong compoimds for development can be minimised by identifying critical success factors and an MAP that will provide the basis for go/no-go decisions. 

These three examples illustrate market-driven research that requires substantial fundamental research to generate the new knowledge that can, in turn, generate intellectual property and provide protection in a long-term market position. I would now like to focus on three critical success factors paramount for rapid innovation from basic research to the marketplace—the three P s. 

The objective of using a mathematical optimization model is to identify network design alternatives that best exploit structural cost differences between various locations and resolve trade-offs between different cost elements such as production cost advantages and additional transporta-tion/tariff costs. Therefore, relationships expressing the costs that will be incurred as a function of cost drivers (decision variables of the model) have to be established. A proper creation of these cost functions is a critical success factor of the overall analysis (cf. Shapiro 2001, p. 234 Vidal and Goetschalckx 1996, p. 13). 

In addition to this general approach to exploring the solution space, the model can also be used to evaluate individual configuration options such as plant expansions, construction of new plants or closure of existing plants. For questions like "what happens if we close a production line at site X" the model has to provide recommendations on where to relocate affected products and calculate the economic impact of the decision. Depending on the critical success factors of the business ("order winning cri-... 

Table 1 Critical success factors for successful modeling applications...

Glockner et al. (2004) and Zoulias et al. (2006) presented a strengths, weaknesses, opportunities and threats (SWOT) analysis related to the introduction of hydrogen technologies (including fuel cells) in stand-alone power systems and also identified critical success factors for a successful introduction of hydrogen in autonomous power systems. 

In principle, the technical problems can be solved if sufficient time and money is available. But the results will not always be as desired, and it will initially be necessary to accept many compromises in terms of scale, yields, reproducibility and cost of production. Given the technical feasibility, the impact of time, money and lower than expected performance tend to be neglected. In the end they may be critical success factors ... 

Outsourcing Clinical Drug Development Activities to Contract Research Organizations (CROs) Critical Success Factors... 

As pharmaceutical companies strive to increase productivity and decrease costs, they must improve their skills in dealing with CROs. This chapter examines the challenges of outsourcing clinical drug development activities and identifies critical success factors for working with CROs. 

Structure-based design is now actively pursued by sizeable groups in both academic institutions as well as in the research departments of pharmaceutical companies. Very tight collaboration with both synthetic chemists as well as with experimental biologists performing the biological assay has turned out to be a critical success factor. This often results in the dissemination of structural information to all scientists involved in the project and, ideally, the persistent use of that information in the process of inventing new active principles. 

There are four key requirements that, programmatically speaking, constitute critical success factors for the desired level of effectiveness of the pharmacometrics enterprise. These requirements stem from the shift in roles of the pharmacometrics enterprise that mandates a clear formalization of intents from the larger drug realization enterprise and provide answers to several key questions What are the actual requirements for the hosting organization What are the implications of deploying a solution to those requirements What resources are available and would be required to pursue such an initiative ... 

Chung TD, Sergienko E, Millan JL (2010) Assay format as a critical success factor for identification of novel inhibitor chemotypes of tissue-nonspecific alkaline phosphatase from high-throughput screening. Molecules 15 3010-3037... 

With the exponential increase in information flow resulting from the ability to make many more compounds and test these in multiple assays, the capture, analysis, and management of data is a critical success factor in drug discovery. 

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