Atmospheric pressure matrix-assisted laser desorption ionization

Moyor, S. C. Marzilli, L. A. Woods, A. S. Laiko, V. V. Doroshenko, V. M. Cotter, R. J. Atmospheric pressure matrix-assisted laser desorption/ionization (AP MALDI) on a quadrupole ion trap mass spectrometer. Int. I. Mass Spectrom. 2003, 226,133-150. [Pg.177]

In contrast to the other ion sources, the MALDI source may operate under high vacuum or under atmospheric pressure. In the latter case the acronym AP-MALDI (atmospheric pressure matrix assisted laser desorption ionization) is used. [Pg.51]

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... [Pg.11]

Atmospheric pressure matrix-assisted laser desorption/ ionization AP- MALDI Photon induced desorption/ ionization Nonvolatile molecular ions Soft method Large molecules... [Pg.18]

Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization... [Pg.37]

Atmospheric-pressure matrix-assisted laser desorption ionization... [Pg.132]

Laiko V, Baldwin M, Burlingame A. Atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry. Anal Chem 2000 72 652-7. [Pg.188]

Steiner, W.E. Clowers, B.H. English, W.A. Hill, H.H., Jr., Atmospheric pressure matrix-assisted laser desorption/ionization with analysis by ion mobility time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. 2004, 18(8), 882—888. [Pg.69]

Bramwell, C.J. Greaser, C.S. Reynolds, J.C. Dennis, R., Atmospheric pressure matrix-assisted laser desorption/ionization combined with ion mobility spectrometry, Int. J. Ion Mobil. Spectrom. 2002, 5, 87-90. [Pg.86]

Typically, MALDl has been performed under low pressure conditions (ca 10 Torr). In recent years, intermediate pressure (IP, 10 to 1 Torr) [10,12-14] and atmospheric pressure (AP) MALDl [15,16] systems have been developed to analyze more labile molecules and for tissue analysis [10]. Atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDl) offers the ability to couple a MALDl source to most commercial instruments, including quadrupole ion traps, because the source uses existing ion optics and vacuum transfer lines of commercial instruments to introduce the ions generated by MALDL A brief discussion of IP-MALDI with ion trap technology is presented, but the primary focus is on the instrumentation aspect of ion trap technology, in particular linear ion trap technology, for direct tissue analysis and imaging MS studies. [Pg.419]

Von Seggern, C.E., Moyer, S.C., and Cotter, R.J. (2003) Liquid infrared atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sialylated carbohydrates. Anal. Chem., 75,... [Pg.97]

Konn, D.O., Murrell, J., Despeyroux, D., Gaskell, S.J. (2005) Comparison of the Effects of Ionization Mechanism, Analyte Concentration, and Ion Cool-times on the Internal Energies of Peptide Ions Produced by Electrospray and Atmospheric Pressure Matrix-assisted Laser Desorption Ionization. J. Am. Soc. Mass Spectrom. 16 743-751. [Pg.268]

Giurato, L., Candura, A., Grasso, G, Spoto, G. (2009) In situ identification of organic components of ink used in books from the 1900s by atmospheric pressure matrix assisted laser desorption ionization mass spectrometry. Appl. Phys. A, 97,263. [Pg.857]

Berkout, V.D., Kryuchkov, S.I., Doroshenko, V.M. (2007) Modeling of ion processes in atmospheric pressure matrix-assisted laser desorption/ionization. Rapid Commun. Mass Spectrom., 21, 2046. [Pg.858]

Salo, P.K., Salomies, H., Harju, K., Ketola, R.A., Kotiaho, T., Yli-Kauhaluoma, I, Kostiainen, R. (2005) Analysis of small molecules by ultra thin-layer chromatography-atmospheric pressure matrix-assisted laser desorption/ ionization mass spectrometry. Journal of the American Society for Mass Spectrometry,16, 906-915. [Pg.1203]

Chapter 6, titled Selection of Ionization Methods of Analytes in the TLC-MS Techniques provides an overview of mass spectrometric techniques that can be coupled with TLC and act as specific detectors in this hyphenated approach. The mass spectrometric techniques discussed in this chapter are secondary mass spectrometry (SIMS), liquid secondary ion mass spectrometry (LSIMS), fast atom bombardment (FAB), matrix-assisted laser desorption/ionization (MALDI), atmospheric pressure matrix-assisted laser desorption/ionization (AP-MALDI), electrospray ionization (ESI), desorption electrospray ionization (DESI), electrospry-assisted laser desorption/ionization (ELDI), easy ambient sonic spray ionization (EASI), direct analysis in real time (DART), laser-induced acoustic desorption/electrospray ionization (LIAD/ESI), plasma-assisted multiwavelength laser desorption/ionization (PAMLDI), atmospheric-pressure chemical ionization (APCI), and dielectric barrier discharge ionization (DBDI). For the sake of illustration, the authors introduce practical examples of implementing TLC separations with detection carried out by means of individual mass spectrometric techniques for the systematically arranged compounds belonging to different chemical classes. [Pg.9]

THIN-LAYER CHROMATOGRAPHY-ATMOSPHERIC PRESSURE MATRIX-ASSISTED LASER DESORPTION/IONIZATION... [Pg.88]

Pribil PA, Patton E, Black G, Doroshenko V, Fenselau C. Rapid characterization ofBacillus spores targeting species-unique peptides produced with an atmospheric pressure matrix-assisted laser desorption/ionization souree. J Mass Spectrom. 2005 40(4) 464-74. [Pg.177]

Keough, T., Lacey, M. P., Strife, R. J. (2001) Atmospheric pressure matrix-assisted laser desorption/ionization ion trap mass spectrometry of sulfonic acid derivatized tryptic peptides. Rapid Commun Mass Spectrom, 15, 2227-2239. [Pg.338]

Trimpin, S. Herath, T. N. Inutan, E. D. Cemat, S. A. Wager-Miller, J. Mackie, K. Walker, J. M. Field-free transmission geometry atmospheric pressure matrix-assisted laser desorption/ionization for rapid analysis of unadulterated tissue samples. Rapid Commun. Mass Spectrom. 2009, 23, 3023-3027. [Pg.210]