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Amiodarone

Decrease in concentration of solutions of amiodarone hydrochloride is found when stored in flexible PVC bags and glass or rigid PVC bottles, and administered with PVC sets. This may be due to the presence of plasticizer, di-2-ethylhexylphthalate.98 [Pg.347]

Amiodarone injection is incompatible with aminophylline, flucloxacillin, heparin, sodium bicarbonate, and sodium chloride solutions.99100 [Pg.347]


Amiodarone. Amiodarone, an iodinated benzofuran derivative that has stmctural similarities to the thyroid hormones (qv), was originally... [Pg.119]

The electrophysiological effects of amiodarone may be a composite of several properties. In addition to prolonging action potential duration and refractory period in ad tissues of the heart, the compound is an effective sodium channel blocker (49), calcium channel blocker (50), and a weak noncompetitive -adrenoceptor blocking agent (51). Amiodarone slows the sinus rate, markedly prolongs the QT interval, and slightly prolongs the QRS duration (1,2). [Pg.121]

Amiodarone dilates arteriolar vascular smooth muscle, especiady coronary arteries, and thus exhibits antianginal effects. Its effects on the peripheral vasculature to decrease resistance leads to a decrease in left ventricular stroke work and a decrease in myocardial oxygen consumption. The dmg rarely produces hypotension that requires discontinuation of the dmg (1,2). [Pg.121]

Dimethyl amino ethyl chloride Amiodarone HCI Brompheniramine maleate Carbinoxamine maleate Chlorpheniramine maleate... [Pg.1629]

III Block of repolarizing potassium channels, prolongation of action potential Amiodarone, Dronedarone, Sotalol, Dofetilide, Ibutilide... [Pg.96]

Since alterations of thyroid fimction by amiodarone are related to the iodine substitution of the drug, the iodine-free derivative dronedarone has been developed with similar electrophysiological effects as amiodarone. It seems to act also as a T3-anatgonist, but does not provoke hyperthyreoidism [1]. [Pg.100]

The risk of atrial flutter is a 2 1 transmission to the ventricles generating a high ventricular rate. The therapeutic goal is to reduce transmission to 3 1 or 4 1 by administration of either (3-adrenoceptor antagonists, Ca2+ channel blockers or amiodarone. Quinidine must not be used in this arrhythmia, since it accelerates AV-conduction due to its vagolytic effect. [Pg.101]

Ventricular extrasystoles are treated only if they may degenerate into life-threatening arrhythmia. In milder forms the proarrhythmic risk of the diugs overshadows their benefits. In such cases (3-adrenoceptor antagonists may be attempted. For the treatment of ventricular extrasystoles, such as series or runs of extrasystoles, amiodarone or sotalol are used. In the absence of structural heart disease, class I anti-arrhythmic diugs can be considered an alternative. However, they may not be administered during the post-infarction period. [Pg.101]

Ventricular fibrillation should be terminated by electrical defibrillation. Alternatively, lidocaine can be injected intravenously. In cases with lower frequency, ventricular tachyarrhythmia class I diugs such as aj marine, flecainide or propafenone are more effective as a result of the use-dependence of lidocaine. For prophylaxis treatment, amiodarone or sotalol may be helpful or the implantation of a cardioverter-defibrillator system. Acute amiodarone (i.v. in higher doses) can also terminate ventricular tachyarrhythmias. This action, however, seems to be mediated by its INa-blocking side effects and not (or less) by its class III like effects. [Pg.101]

Maintenance doses widely vary among patients (e.g., from 1 to 20 mg/day for warfarin), and are influenced by diet (variable vitamin K intake) and medications that affect coumarin metabolism (decreased drug clearance e.g., cotrimoxazole, amiodarone, erythromycin increased clearance e.g., barbiturates, carbamaze-pine, rifampin). Thus, regular monitoring is needed... [Pg.109]

Verapamil, diltiazem, amiodarone Diminished renal and nonrenal excretion ... [Pg.327]

Concurrent use of the fluoroquinolones with theophylline causes an increase in serum theophylline levels. When used concurrently with cimetidine, the cimetidine may interfere with the elimination of the fluoroquinolones. Use of the fluoroquinolones with an oral anticoagulant may cause an increase in the effects of the oral coagulant. Administration of the fluoroquinolones with antacids, iron salts, or zinc will decrease absorption of the fluoroquinolones. There is a risk of seizures if fluoroquinolones are given with the NSAIDs. There is a risk of severe cardiac arrhythmias when the fluoroquinolones gatifloxacin and moxifloxacin are administered with drains that increase the QT interval (eg, quini-dine, procainamide, amiodarone, and sotalol). [Pg.93]

CHH14O3 106-31-0) see Acebutolol Amiodarone Bucladesine sodium Bunamiodyl lopanoic acid lophenoic acid... [Pg.2320]


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Acenocoumarol Amiodarone

Agalsidase beta Amiodarone

Amiodarone Amprenavir

Amiodarone Anaesthetics, general

Amiodarone Antihistamines

Amiodarone Aprindine

Amiodarone Astemizole

Amiodarone Atazanavir

Amiodarone Atenolol

Amiodarone Azithromycin

Amiodarone Beta blockers

Amiodarone Calcium-channel blockers

Amiodarone Carbamazepine

Amiodarone Carvedilol

Amiodarone Ciclosporin

Amiodarone Cimetidine

Amiodarone Ciprofloxacin

Amiodarone Clarithromycin

Amiodarone Clonazepam

Amiodarone Colestyramine

Amiodarone Coumarins

Amiodarone Cyclophosphamide

Amiodarone Cyclosporine

Amiodarone Dextromethorphan

Amiodarone Digitoxin

Amiodarone Digoxin

Amiodarone Diltiazem

Amiodarone Disopyramide

Amiodarone Eplerenone

Amiodarone Erythromycin

Amiodarone Fentanyl

Amiodarone Flecainide

Amiodarone Fosamprenavir

Amiodarone Gatifloxacin

Amiodarone Grapefruit juice

Amiodarone Halothane

Amiodarone Ibutilide

Amiodarone Indinavir

Amiodarone Levofloxacin

Amiodarone Lidocaine

Amiodarone Lopinavir

Amiodarone Loratadine

Amiodarone Lovastatin

Amiodarone Macrolides

Amiodarone Methotrexate

Amiodarone Metoprolol

Amiodarone Mexiletine

Amiodarone Mizolastine

Amiodarone Moxifloxacin

Amiodarone Orlistat

Amiodarone Oxygen

Amiodarone Phenytoin

Amiodarone Pravastatin

Amiodarone Procainamide

Amiodarone Propranolol

Amiodarone Protease inhibitors

Amiodarone Quinidine

Amiodarone Quinolones

Amiodarone Rifampicin

Amiodarone Rifampin

Amiodarone Sertraline

Amiodarone Simvastatin

Amiodarone Sirolimus

Amiodarone Sotalol

Amiodarone Sparfloxacin

Amiodarone Statins

Amiodarone Tacrolimus

Amiodarone Terfenadine

Amiodarone Theophylline

Amiodarone Thiopental

Amiodarone Vardenafil

Amiodarone Verapamil

Amiodarone Warfarin

Amiodarone adverse effects

Amiodarone adverse reaction

Amiodarone anaphylaxis

Amiodarone antiarrhythmic effects

Amiodarone arrhythmia with

Amiodarone atrial fibrillation

Amiodarone binding

Amiodarone cardiovascular effects

Amiodarone channel inhibition

Amiodarone defibrillator

Amiodarone derivatives

Amiodarone dosage

Amiodarone dosing

Amiodarone drug interactions

Amiodarone glucocorticoids

Amiodarone heart failure

Amiodarone hepatotoxicity

Amiodarone hydrochloride

Amiodarone infiltrates

Amiodarone interactions

Amiodarone liver

Amiodarone liver cirrhosis

Amiodarone liver injury

Amiodarone mechanism of action

Amiodarone pharmacokinetics

Amiodarone pharmacological effects

Amiodarone pharmacology

Amiodarone plasma concentrations

Amiodarone pulmonary toxicity

Amiodarone secretion

Amiodarone side effects

Amiodarone steatohepatitis

Amiodarone structures

Amiodarone syndrome

Amiodarone tachydysrhythmias

Amiodarone thyroid disorders with

Amiodarone thyroid dysfunction

Amiodarone thyroid gland

Amiodarone thyroid-stimulating hormone

Amiodarone thyrotoxicosis with

Amiodarone toxicity

Amiodarone values

Amiodarone ventricular

Amiodarone ventricular arrhythmias caused

Amiodarone with chloroquine

Amiodarone with digoxin

Amiodarone with implantable cardioverter

Amiodarone with quinolones

Amiodarone with statins

Amiodarone with telithromycin

Amiodarone with warfarin

Amiodarone, dysrhythmias

Amiodarone, metabolite

Amiodarone-induced hypothyroidism

Amiodarone-induced pulmonary toxicity

Amiodarone-induced thyrotoxicosis

Antiarrhythmic agents amiodarone

Antiarrhythmic drugs with amiodarone

Antiarrhythmics amiodarone

Antidysrhythmics amiodarone

Canadian Amiodarone Myocardial

Canadian Amiodarone Myocardial Infarction Arrhythmia Trial

Canadian Amiodarone/Arrhythmia Myocardial

Cardiac arrest amiodarone

Cardiovascular agents amiodarone

Cordarone - Amiodarone hydrochloride

Cordarone X - Amiodarone hydrochloride

EMIAT Amiodarone Trial

European Myocardial Infarction Amiodarone Trial

Fever amiodarone

Flecainide with amiodarone

Goiter amiodarone

Hyperthyroidism amiodarone

Hyperthyroidism from amiodarone

Hyperthyroidism with amiodarone

Optic nerve amiodarone

Potassium channels amiodarone

Procainamide with amiodarone

Quinidine with amiodarone

Respiratory amiodarone

Skin photosensitivity amiodarone

Skin pigmentation amiodarone

Sudden cardiac death amiodarone effect

Thrombocytopenia amiodarone

Trazodone amiodarone

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