Atenolol Amiodarone

Noninterfering amiodarone, atenolol, disopyramide, labetalol, lignocaine, lorcainide, methyldopa, nifedipine, prenalterol, propafenone, sotalol, timolol... 

Clinically important, potentially hazardous interactions with acebutolol, amiodarone, aspirin, atenolol, atorvastatin, betaxolol, carbamazepine, carteolol, celiprolol, donidine, dabigatran, dantrolene, digoxin, dofetilide, epirubicin, eplerenone, erythromycin, esmolol, eucalyptus, everolimus, lovastatin, metoprolol, mistletoe, nadolol, oxprenolol, penbutolol, pindolol, propranolol, quinidine, ranolazine, sibutramine, simvastatin, timolol, trabectedin... 

The possible cardiac functions of amiodarone are attributed to tissue hypothyroidism.55 Ide et al177 showed that this drug protect cardiac myocytes from the canine left ventricular free wall against oxidative stress-mediated injury by H202, while dis-opyramide and atenolol had no such effects. 

Also Emalyzed acebutolol, acepromazine, acetophenazine, N-acetylprocainamide, albuterol, alprenolol, amethocaine, amiodarone, amitriptyline, antazoline, atenolol, azacy-clonal, bamethane, benactyzine, benperidol, benzethidine, benzocaine, benzoctamine, benzphetamine, benzquinamide, bromhexine, bromodiphenhydramine, bromperidol, brompheniramine, brompromazine, buclizine, bufotenine, bupivacaine, buprenorphine, butacaine, butethamate, chlorcyclizine, chlorpheniramine, chlorphenoxamine, chlorpren-aline, chlorpromazine, chlorprothixene, cimetidine, cinchonidine, cinnarizine, clemastine, clomipramine, clonidine, cocaine, (yclazocine, cyclizine, cyclopentamine, cyproheptadine, deserpidine, desipramine, dextromoramide, dextropropoxyphene, dicyclomine, diethylcar-hamazine, diethylpropion, diethylthiambutene, ciihydroergotamine, dimethindene, di-... 

M KCl were performed on the PCA 101 titrator. .. at 25 °C for amiodarone, metoprolol and ramipril and at 37 °C for atenolol. The pKa values of metoprolol, atenolol, and ramipril were determined in 0.15M KCl. For die extrapolation of the aqueous pKa of amiodarone, we used the Yasuda-Shedlovsky plot (4). Apparent pKa values (+ log [H2O]) in the medianol/O.lSM KCl mixtures at ratios between 47 and 71%(w/w) methanol were plotted against the inverse dielectric constant... and the pKa of the molecule in 100% aqueous solution was extrapolated by linear regression." surface H2O Ferreira J, Brasseur R, Chatelain P and Ruysschaest J, Properties of... 

A 64-year-old woman was treated for hypertrophic cardiomyopathy with amiodarone 1.2 g daily and atenolol 50 mg daily. Five days later the atenolol was replaced by metoprolol 100 mg daily. Within 3 hours she complained of dizziness, weakness and blurred vision. On examination she was found to be pale and sweating with a pulse rate of 20 bpm. Her systolic blood pressure was 60 mmHg. Atropine 2 mg did not produce chronotropic or haemodynamic improvement. She responded to isoprena-line (isoproterenol). Severe hypotension has been reported in another patient taking sotalol when intravenous amiodarone (total dose 250 mg) was given. Another report describes cardiac arrest in one patient on amiodarone, and severe bradycardia and ventricular fibrillation (requiring defibrillation) in another, within 1.5 and 2 hours of starting to take propranolol. ... 

Lear J, Levartowdcy D, Sharon C, Faifel Z. Amiodarone and p-adreneigic blockers an inter-actionwithmetxjprololbutnotwith atenolol. /4m(1988) 11 206-7. 

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