Accelerators development

P. J. Baker, ed.. National Institute of Allergy and Infectious Diseases, The Jordan Report, Accelerated Development of Vaccines, 1993, NIH, Bethesda, Md. 

Efforts to develop commercially viable EV versions of advanced battery systems continue. The ultimate goal is to develop battery technology suitable for practical, consumer-acceptable electric vehicles. The United States Advanced Battery Consortium (USABC) has been formed with the express purpose of accelerating development of practical EV batteries (83). 

Although is it possible to delineate the requirements for a suitable catalytic system, reducing this to practice is a daunting prospect. As is the case in many examples of asymmetric catalysis, empirical survey provides the initial leads which, aided by an understanding of the process, allows for accelerated development. 

Standard control practices developed within these limitations have taken all the various factors into consideration. Entomologists recognize the inadequacy of many of the recommended control measures. They have initiated the effort to develop new and more effective insecticides and welcomed the interest and assistance of others. The recent accelerated development of new insecticides has opened new fields and done much to stimulate public interest in insect control. Much more needs to be learned than to know that the new materials will kill insects, before their true worth can be determined. We must determine many things. Knowledge of the effect on beneficial insects, wild life, soil, and machines is important. Of greater importance is Are they safe for the operator and for those who handle and use the product ... 

New regulations Accelerating development of cancer chemotherapy New drug-delivery systems... 

Thus, for example, Matutes et al.9 show in a formal model that in basic or breakthrough innovations, protection on the basis of scope generates higher levels of welfare than period-based protection. The reason for this is that the period in which rivals can introduce applications is shorter and the patent holder can decide when to exert his or her rights. Nevertheless, it is also true that this can accelerate developments that do not generate additional value if the calculation of the reward given to the second-level innovator is excessive. The concept of the right reward for the two types of innovation is not easy to put into practice. 

Enchira Biotechnology, EBC, which was headquartered near Houston, TX, used to be the largest biotechnological platform devoted to the development of biorefining processes. EBC acquired Energy Biosystems in June 2000 and continued the R D activities on BDS during the last years. This company applied directed evolution methods to accelerate development and commercialization of gene-based products for the industrial... 

Nicewonger R, Baldino C, Evans M (2003) The accelerated development of an optimized synthesis of 1,2,4-oxadiazoles. Tetrahedron Lett 44 9337-9341 Ondruschka B, Nuchter M, Bonrath W (2004) Microwave assisted synthesis— a critical technology overview. Green Chem 6 128-141 Regan J, Breitfelder S Cirillo P (2002) Pyrazole urea-based inhibitors of p38 MAP kinase from lead compound to clinical candidate. J Med Chem 45 2994-3008... 

Pharmaceuticals, 18 682-721. See also Food and Drug Administration (FDA) Large-scale pharmaceutical synthesis Pharmaceutical products accelerated development/review for, 18 697... 

It is accepted that many widely used latex vulcanisation accelerators - dithiocaibamates, thiurams and thiazoles - are capable of producing Type IV allergic response in certain individuals within the population and may also possess increasingly unacceptable eco-toxic and acute toxicity profiles. Thiurams and dithiocaibamates (derived from secondary amines) can also produce potentially harmful N-nitrosamines. Four safer accelerators developed and commercialised by Robinson Brothers are described. They are designed to reduce or eliminate the impact of the above problems using sustainable technology. At the same time these accelerators produce equivalent technological performances to those conventionally used. 10 refs. 

Accelerated Development/Review A drug for the treatment of serious or life-threatening diseases for which there are no alternative therapies may receive expedited review and approval. A condition for the approval is that the Sponsor undertakes to continue with further clinical trials after approval to confirm the efficacy of the drug. 

A second catalyst subsequently introduced by a second manufacturer was also considered acceptable and utilized successfully. However, the stimulus of our work undoubtedly had a favorable impact on commercial producers, resulting in accelerated development and commercial introduction of new and superior-performing RCC catalysts, and at reduced cost. 

Most Intensification treatments accelerate development as well as increase the effective speed of the photographic material. The gold Intensification is especially notable in this respect, and is of interest in relation to the mechanism of development. A simple motion picture positive film responds well to the gold treatment, which consists simply in bathing the exposed film for a few minutes in a solution containing the aurous thiocyanate complex in the presence of excess thiocyanate and bromide ions. Figure 7 shows the developed densities for several... 

Standardisation. The standardisation of systems is needed for accelerated development. Up to now, no unique and acknowledged evaluation criteria for fuel cells and components exists - which causes huge hurdles for new players in this technology area. Safety aspects need to be fitted to the emerging fuel cell technology. International standards must be generated. 

Thill, C. A., Peloquin, S. J. (1995). A breeding method for accelerated development of cold chipping clones in potato. Euphytica, 84, 73-80. 

Food consumption of adults decreased after day 16 accelerated development of pluteal stages all developmental stages had increased activities of acid phosphatase... 

Accelerated development/reviewcan be used under two special circumstances when approval is based on evidence of the product s effect on a "surrogate endpoint," and when the FDA determines that safe use of a product depends on restricting its distribution or use. A surrogate endpoint is a laboratory finding or physical sign that may not be a direct measure of how a patient feels, functions, or survives, but is still considered likely to predict therapeutic benefit for the patient. 

The availability of energy in the form of ionizing radiations has recently increased markedly. This increase is likely to continue for some years. A portion of this energy will be potentially available as a result of accelerator development and facilities for the production of radioisotopes. Another large supply of this energy will be produced as a necessary consequence of the anticipated wide-scale use of the power reactor. 

Reduction in the time and expense for approving new biopharmaceuticals may accelerate development of new products and processes. The increase in the number of new biotechnology drugs and other products that... 

MCMILLAN, EDWIN M. (1907-1991). An American physicist who won the Nobel prize in chemistry in 1951 along with Glenn T. Seaborg lor their discoveries In the chemistry of the transuranium elements. His work included research in nuclear physics and particle accelerator development as well as microwave radar and sonar. He and his colleagues discovered neptunium and plutonium. He was the recipient of the Atoms for Peace prize in 1963. His Ph D. in Physics was awarded from Princeton University. 

Ceolin G et al (2009) Accelerated development procedure for molecularly imprinted polymers using membrane filterplates. J Comb Chem ll(4) 645-652... 

Thus, an R D program can be readily accelerated by tapping into your technology platform and internal network to select focused team members. Commonly, there is little or no physical movement although a program manager will have authority and accountability for the entire team. With this foundation, a well-designed team can achieve a rapid start and accelerate development. 

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