Responses allergic

The adverse effects iaclude digestive disturbances, neurological symptoms, and manifestations of allergic responses. As many as half of the patients taking it are iacapacitated by some of these adverse reactions for several hours. Whether these symptoms are caused by hypersensitivity to the dmg, the parasite, or by a manifestation of the disease is not known. Overall, effects are dose-related and transient. 

SENSITIZER A substance that causes little or no reaction in a person upon initial exposure but which will provoke an allergic response on subsequent exposures. 

Health Hazards Information - Recommended Personal Protective Equipment Chemical goggles face shield oil-resistant gloves Symptoms Following Exposure Contact with eyes causes mild inflammation. Contact with skin may produce allergic response General Treatment for Exposure EYES or SKIN remove excess oil with cloth or absorbent paper then wash with soapy water and flush with clear water consult a physician Toxicity by Inhalation (Threshold Limit Value) Data not available Short-Term Inhalation Limits Data not available Toxicity by Ingestion Grade 0 LDjj > 15 g/kg Late Toxicity Data not available Vapor (Gas) Irritant Characteristics Data not available Liquid or Solid Irritant Characteristics Data not available Odor Threshold Data not available. 

Allergic alveolitis An allergic response to inhalation of organic particles that involves inflammation of the small terminal branches of the bronchioles. Symptoms include coughing, increased production of mucus, fever, fatigue, and muscle aches. 

Allergic response The release of antibodies by the immune system in response to foreign molecules in the body. 

Humidifier fever An illness caused by the growth of microorganisms in air cooling coils. These microorganisms or their generated toxins may be carried in the airstream to the conditioned space, causing an allergic response in susceptible people. 

Corticosteroids exhibit a wide range of physiological effects. One important function is to assist in maintaining the proper electrolyte balance in body fluids. They also play a vital regulatory role in the metabolism of car bohydrates and in mediating the allergic response. 

Platelet activating factor (PAF) was first identified by its ability (at low levels) to cause platelet aggregation and dilation of blood vessels, but it is now known to be a potent mediator in inflammation, allergic responses, and shock. PAF effects are observed at tissue concentrations as low as 10 M. PAF causes a dramatic inflammation of air passages and induces asthma-like symptoms in laboratory animals. Toxic-shock syndrome occurs when fragments of destroyed bacteria act as toxins and induce the synthesis of PAF. This results in a drop in blood pressure and a reduced... 

In addition to its role in preventing scurvy (see Human Biochemistry box Ascorbic Acid and Scurvy and also Chapter 6), ascorbic acid also plays important roles in the brain and nervous system. It also mobilizes iron in the body, prevents anemia, ameliorates allergic responses, and stimulates the immune system. 

The term antihistamines describes drags which bind to the Hi-histamine receptor and antagonize (block) the histamine effect in Type I allergic responses. 

The activation of mast cells by allergen initiates the asthma symptoms within minutes after allergen contact, the early allergic response (EAR), within horns the late allergic response (LAR), and within years and after rqDeated asthma episodes, chronic airway inflammation, airway remodeling, and airway hyperresponsiveness. 

In summary, preliminary results from two animal models (rabbit and mouse) indicate that poly(N-palmitoylhydroxyproline ester) elicits a very mild, local tissue response that compares favorably with the responses observed for established biomaterials such as medical grade stainless steel or poly(lactic acid)/poly(glycolic acid) implants. At this point, additional assays need to be performed to evaluate possible allergic responses, as well as systemic toxic effects, carcinogenic, teratogenic, or mutagenic activity, and adaptive responses. 

Liu Y Zhu M, Nishida K, Hirano X Zhang W An essential role for RasGRP 1 in mast cell function and IgE-mediated allergic response. J Exp Med 2007 204 93-103. 

Bansal G, Xie Z, Rao S, Nocka KH, Druey KM Sup- 54 pression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13. 

Platinum is used as a catalyst for nitric and sulphuric acid production, in petroleum refining and in catalytic mufflers to control air pollution. Platinum salts can cause respiratory complaints, asthma, and platinosis , an allergic response. Allergic dermatitis may also result from exposure to soluble platinum salts and once subjects have been sensitized it generally precludes continued occupational exposure at any level. The 8 hr TWA OEL for platinum metal is 5 mg/m but for soluble platinum salts it is only 0.002 mg/m. Handling precautions must include containment where possible, ventilation, personal protection, and the screening out of individuals who have become sensitized. 

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