Weight-reduction drug

An article in the New England Journal of Medicine reports that 24 patients taking fen-phen, a combination of two weight-reduction drugs, have an unusual form of heart disease involving abnormalities in the heart valves. The FDA approves Baycol, an anticholesterol statin drug made by Bayer. It costs less than competitors but turns out to have a rare but serious side effect that destroys muscle tissue. 

During the 1930s, dinitrophenol was touted as a weight-reduction drug. Dinitrophenol acts to uncouple... 

One factor in the reduction of healthcare expenditure is home medical care, which involves adaptations of the methods of care. These uses dictate particular requirements for sterility, safety, reliability, weight and facility of use. Plastics can bring solutions in the fields of single-use products, unbreakable equipment and weight reduction, for example, in the syringes, tubes and pumps for drug injections and apparatus for ambulatory dialysis. 

Hypertension infrequently results from another disease, such as a catecholamine-secreting tumor (pheochro-mocytoma) in most cases the cause carmot be determined essential (primary) hypertension. Antihypertensive drugs are indicated when blood pressure cannot be sufficiently controlled by means of weight reduction or a low-salt diet. In principle, lowering of either cardiac output or peripheral resistance may decrease blood pressure (cf p. 306,... 

Drugs with thyroid hormone activity, alone or with other therapeutic agents, have been used for the treatment of obesity. In euthyroid patients, doses within the range of daily hormonal requirements are ineffective for weight reduction. Larger doses may produce serious or even life-threatening manifestations of toxicity, particularly when given in association with sympathomimetic amines such as those used for their anorectic effects. 

The cornerstone of treatment in primary hyperlipidemia is diet restriction and weight reduction. Limit or eliminate alcohol intake. Use drug therapy in conjunction with diet, and after maximal efforts to control serum lipids by diet alone prove unsatisfactory, when tolerance to or compliance with diet is poor or when hyperlipidemia is severe and risk of complications is high. Treat contributory diseases such as hypothyroidism or diabetes mellitus. 

This consists of weight reduction, physical activity, moderation of dietary sodium and high dietary potassium intake. Implementation of lifestyle modifications should not delay the start of effective antihypertensive drug therapy. Patients with renal insufficiency with proteinuria greater than 1 g/day should be treated to a BP goal of 125/75 mmHg ... 

Urine volume, creatinine clearance, BUN, electrolytes, reduction in edema, increased diuresis, decrease in body weight, reduction in blood pressure, glucose, uricacid, serum calcium (tetany), tinnitus, vertigo, hearing loss (especiallyin those at risk for ototoxicity—IV doses > 120 mg concomitant ototoxic drugs renal disease)... 

Until the 1970s, methamphetamines were used for a variety of medical conditions in the United States. However, with the growing abuse of these powerful drugs, the federal government imposed strict controls on their usage and prescription. Currently, the use of methamphetamines in medicine are restricted for only a few types of medical conditions, including weight reduction for obese patients, narcolepsy, and attention-deficit disorder (ADD). 

Anorectic feature of major depressive disorder. Drug that reduces appetite used in weight reduction. 

The total fat intake must be reduced to achieve weight reduction by diet therapy.70 Dietary recommendations also include a reduction in saturated fatty acids. Drug therapy must be started only after confirmation of lipid levels such as cholesterol, triglycerides, LDL, and HDL. Adequate trial must be initiated with modification of dietary therapy, only failing which drug therapy must be started. 

Treatment Weight reduction (if necessary). Dietary restriction of cholesterol and alcohol. Drug therapy includes rTiacir nc lofibmt or emfibrozil) Movastatir or Tievastatin) ... 

Treatment Weight reduction (if necessary) is of primary Importance. Dietary restriction of controlled carbohydrate, modified fat, low alcohol consumption. If necessary, drug therapy includes niacin and/or gemfibrozil (or clofibrate), or lovastatin (or mevastatin). 

Drugs used to increase HDL levels (fibrates, nicotinic acid, and statins) in otherwise normal people do not have the same effect in patients with Tangier disease. Therefore, it is necessary to identify and treat other risk factors associated with CAD. Exercise, weight reduction, dietary cholesterol and saturated fat reduction, and smoking cessation are the first line in management of low HDL cholesterol. Dietary management with low fat intake is beneficial in reducing the risk for CAD, as well... 

It is worth noting that under the definition of effective as applied, all components of a combination product must contribute to the drug s labeled indications. Thus, an appetite suppressant might be demonstrated to be effective as an aid to weight loss, but if the same appetite suppressant were mixed with vitamins as a protection against the effects of eating less, the product would be labeled ineffective, as the vitamins had no role in weight reduction. 

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