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Toxicity and Tolerance

Recombinant strain Carbon source Titer (g/L) P/S (mol/mol) 2p (g/L-h) Aeration condition Reference [Pg.397]

Batch cultivation E. coli BL21 dhaB aldH Glycerol 0.6 0.48 0.02 Aerobic Raj et al. (2008) [Pg.397]

pneumoniae AK pduP Glycerol 1.4 (8.4) 0.07 0.06 Aerobic Luo etal. (2011b) [Pg.397]

coli BL21 mcr acc pntAB Glucose 0.2 0.02 0.01 Aerobic Rathnasingh et al. [Pg.397]


Ad.TNF gene therapy is presently in clinical trials in patients receiving radiotherapy. An open-label, phase I, dose-escalation study of tumor necrosis factor-alpha (TNFerade) gene transfer with radiation therapy for locally advanced, recurrent, or metastatic solid tumors is currently accruing patients and has several endpoints (82), including toxicity and tolerable dose. Pharmacokinetics will be evaluated and biological correlates will determine the histologic response to therapy. [Pg.374]

It has not been possible so far to establish that Cr is an essential element required by plants, however, addition of Cr to soils deficient in the element has been shown to increase growth rates and yields of potatoes, maize, rye, wheat or oats (Scharrer and Schropp, 1935 Huffman and Allaway, 1973 Bertrand and De Wolf, 1986). Nickel appears to be an essential element for plants (Farago and Cole, 1988). Zerner and coworkers (Dixon et al., 1975) demonstrated that urease isolated from jack bean (Canavalia ensiformis) was a nickel enzyme. Eskew et al. (1983) have shown that Ni is an essential micronutrient for legumes. Most plants contain nickel in the range 1 - 6 mg kg-1 (Vanselow, 1966 Hutchinson, 1981). The uptake of Ni is enhanced by low pH values, and available nickel increases at pH less than 6.5 as a consequence of the breakdown of Ni complexes in the soil with Fe and Mn oxides. Uptake of nickel by plants and questions of toxicity and tolerance have been reviewed by Farago and Cole (1988). Nickel toxicity toward plants has been reviewed by Vanselow (1966) and Hutchinson (1981). [Pg.51]

The search for the exact sites of ion and compound deposition in plants and the nature of the chemical species involved has been carried out with a number of aims The elucidation of various mechanisms of phytochemical importance mineral uptake and utilisation toxicity and tolerance exhibited by many individual species and the study of plants that accumulate or hyperaccumulate metals. The literature for a number of individual elements to the late 1970s has been reviewed (Farago, 1981) and the phytochemistry of metal hyperaccumulators has been reviewed by Baker and Brooks (1989). [Pg.266]

The use of cell tissue culture methods in the study of metal toxicity and tolerance would appear to offer great potential scope. [Pg.279]

Dettham, W-D., Yang, Z.P., Milatovic, D. (1999). Different role of carboxylesterases in toxicity and tolerance to paraoxon and DFP. Chem. Biol. Interact. 119-20 445-54. [Pg.808]

Arthur 0. Little, Inc., and Sterllng-Wlnthrop Research Institute 1968 Supplement 5. Additional Toxicity and Tolerance Tests vlth 226,086 and 226,169. Quarterly Report, Contract Ko. DA-18-108-AMC-103 (A). [Pg.267]

Dragicevic V., Simic M, Stefanovic L., Sredojevic S. Possible toxicity and tolerance patterns towards post-emergence herbicides in maize inbred lines. Fresenius Environmental Bulletin 2010 19(8) 1499-1504. [Pg.220]

Hossain MA., Piyatida P., da Silva JAT., Fujita M. Molecular mechanism of heavy metal toxicity and tolerance in plants central role of glutathione in detoxification of reactive oxygen species and methylglyoxal and in heavy metal chelation. Journal of Botany 2012 Article ID 872875, 37 pages. [Pg.221]

Montenero, A. S., Toxicity and tolerance of tryptophan and its metabolites, (Italian), Acta Vitaminol. Enzymol., 32, 188, 1978. [Pg.186]

Brown TA and Shrift A (1982) Selenium toxicity and tolerance in higher plants. Biol Rev Camb Philos Soc 57 59-84. [Pg.301]

Matsumoto H (2002) Plant roots under aluminum stress Toxicity and tolerance. In Waisel Y, Eshel A and Kafkafi U, eds. Plant roots the hidden half 3rd edn, pp. 821-838. Marcel Dekker, New York. [Pg.655]

Seaward, M.R.D., 1974. Some ob.servations on heavy metal toxicity and tolerance in lichens. Lichenologist 6, 158-164. [Pg.321]

Gupta, R, C.. Patterson, G. T,. and Dettbarn, W.-D. (1986). Mechanisms of toxicity and tolerance tt) diisopropylpho.spho-rofluoridatc at the neuromuscular junction of the rat. Toxicol. Appl. Pharmacol. 84,541-550. [Pg.265]

Schulze, G. E., and J. A. Dougherty. 1988. Neu-robehavioral toxicity and tolerance to the herbicide 2,4-dichlorophenoxyacetic acid n-butyl ester (2,4-D ester). Fundam. Appl. Toxicol. 10(3) 413-24. [Pg.810]

Skramlik, E.V. 1959. On the toxicity and tolerance of ethereal oils. Pharmazie 14 435-445. [Pg.868]

Koizumi, M. Ema, M. Hirose, A. Kurokawa, Y. Hasegawa, R. No observed adverse effect levels of phthalate esters on reproductive and developmental toxicity, the differences with age and species in testicular toxicity, and tolerable daily intake of DEHP. Jpn. J. Food Chem. 2001, 8, 1. [Pg.1142]

No doubt there are a great number of products which could be studied along these lines, still bearing in mind, however, that, under present regulations, most of these processes can fail on pure toxicity and tolerance issues. [Pg.613]

Thousands of surfactants are produced commercially worldwide, with applications ranging from pharmaceuticals and food additives to soaps and detergents. Surfactants are typically classified as either anionic, cationic, nonionic or anq>hoteric depending upon the nature of their hydrophilic head group. Nonionic surfactants are widely used in agricultural applications because of their relatively low cost, generally low toxicity, and tolerance to varying solution conditions (e.g., electrolyte concentration). The most common nonionic... [Pg.232]

A number of DPP-IV inhibitors have recently been tested for selectivity to DPP-IV, FAP, DPP8, and DPP9 enzymes [45]. In that study, individually selective compounds for DPP-IV, DPP8/9, and FAP were identified, which allowed an evaluation of the potential toxicity and tolerability of each type of inhibition The DPP8/9... [Pg.182]

Therefore, it could be concluded that, the essentiality of Se for higher plants is still unproven, but Se is considered a beneficial nutrient for many plant species. This review focuses on the biochemical responses of plants to Se, the assimilation of Se in plants and possible incorporation into proteins. Molecular approaches to understanding Se toxicity and tolerance have increased the knowledge of mechanisms of action, and the molecular biology of Se in transgenic plants is detailed with special reference to the similarity with sulphur metabolism, S/Se transporters and important assimilation enzymes. [Pg.242]

Blau, P.A., P. Feeny, L. Contardo D.S. Robson. 1978. Allylglucosinolate and herbivorous caterpillars a contrast in toxicity and tolerance. Science 200 1296-1298. [Pg.262]


See other pages where Toxicity and Tolerance is mentioned: [Pg.172]    [Pg.42]    [Pg.230]    [Pg.300]    [Pg.662]    [Pg.529]    [Pg.295]    [Pg.530]    [Pg.257]    [Pg.568]    [Pg.381]    [Pg.396]    [Pg.194]    [Pg.127]    [Pg.224]    [Pg.235]    [Pg.253]    [Pg.872]   


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Tolerance toxicity

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