Salicylic acid, sodium salt

C7Hft03 69-72-7) see Acetylsalicylic acid Balsalazide sodium Flavoxate Hydroxyethyl salicylate Mesalazine Salazosulfapyridine Salsalate salicylic acid sodium salt... [Pg.2440]

CjHjNaO, 113-24-6) see Flurbiprofen sodium salicylate see under salicylic acid sodium salt sodium 3-sulfobenzoate... [Pg.2441]

Salicylic aldehyde is prepared electrolytically by the reduction of salicylic acid (sodium salt) to the aldehyde. The ordinary type of diaphragm cell is used with a mercury cathode, using boric acid and sodium sulfate as catholyte. A current density of 6 amp. per sq. dm. is used, and the temperature is kept between 15° and 18° by means of a freezing mixture. The aldehyde is fixed as soon as formed by means of sodium bisulfite, and is recovered by means of acid hydrolysis and steam distillation. Up to the present stage of the process the best yield obtainable is 55 per cent. [Pg.40]

The purpose of this research was to study the experimental details for the preparation of salicylic aldehyde by the reduction of salicylic acid (sodium salt) electrolytically. [Pg.40]

In 1906 Dr. Hugo Weil patented a process (3) for the reduction of salicylic acid to salicylic aldehyde electrolytically. However, a number of important experimental details were omitted and no yields were stated. Two years later an article by Carl Mettler (4) appeared on the electrolytic reduction of salicylic acid (sodium salt) to salicylic aldehyde which was identical with the patent of Weil. [Pg.41]

It is found that the use of sodium bisulfite materially increases the yield of salicylic aldehyde. Further, that the lower temperatures (15° to 18°) favor the yield of salicylic aldehyde. At higher temperatures less salicylic aldehyde is produced and more of the resinous product. Up to a current density of 8 amp./sq. dm. the yield of salicylic aldehyde is increased. Intermittent electrolysis or stirring after electrolysis is necessary for good current efficiency since a sodium amalgam is built up during the electrolysis. Increasing the time of electrolysis seems to increase the quantity of resin formed. Increasing the concentration of salicylic acid (sodium salt) has little or no effect. [Pg.43]

Salicylic acid sodium salt. See Sodium salicylate... [Pg.3872]

CAS 54-21-7 EINECS/ELINCS 200-198-0 Synonyms 2-Hydroxybenzoic acid monosodium salt o-Hydroxybenzoic sodium salt Salicylic acid sodium salt Sodium-o-hydroxybenzoate ... [Pg.4107]

Salicylic acid, sodium salt - 739 Sal soda (see Sodium carbonate)... [Pg.951]

SYNS p-AMINOSALICYLATE SODIUM p-AMINO-SALICYLIC ACID SODIUxM SALT BACTYLAN LEPASEN NATRI-PAS NIPPAS PAMISYL SODIUM PASADE PASALON-RAKEET PASNAL PASSODICO SALVIS SANIPIROL SODIOPAS SODIUM AMINOSALICYLATE SODIUM p-AxMINOSALICYLIC ACID TUBERSAN... [Pg.1241]

SYNS ALYSINE ARDALL AROALL CLIN DIURETIN ENTEROSALICYL ENTEROSALIL 2-HYDROXYBENZOIC ACID MONOSODIUM SALT o-HYDROXYBENZOIC SODIUM SALT IDOCYL NOVLLM KER. SALICYL KEROSAL MAGSALYL NADISAL NEO-SALICYL PARBOCYL-REV SALICYUC ACID, SODIUM SALT SAUSOD SALSONIN SODIUM-o-HYDROXYBENZOATE SODIUM SALICYLIC ACID... [Pg.1268]

Both salicylic acid and sodium salicylate (its sodium salt) were widely used analgesics in the nineteenth century, but both had undesirable side effects. Salicylic acid irritated the mucous membranes of the mouth and stomach, and sodium salicylate was too sweet for most patients. Aspirin, a synthetic compound, was first sold in 1899 after Felix Hoffman, a German chemist at Bayer Company, developed a feasible commercial synthesis. Hoffman s work was motivated by personal reasons his father suffered from rheumatoid arthritis and was unable to tolerate the sweet taste of sodium salicylate. [Pg.697]

Pyrogallic acid Various organic compounds l,4-cyclohexanedione(tetrahydroquinone) 3-alizarinsulfonic acid sodium salt Salicylic acid > 5-suIfosalicylic acid / Ameta Khandia (1982) Chopin-Dumas (1981) Farage Janjic (1981-1, 2, 3) Gupta et al. (1981) Gupta Srinivasulu (1981)... [Pg.101]

ACETIC ACID, LEAD(II) SALT TRIHYDRATE (6080-56-4) Pb(C2H302)2 3H20 Contact with acids forms acetic acid. Incompatible with oxidizers, bases, acetic acid alkalis, aUcylene oxides, ammonia, amines, bromates, carbonates, citrates, chlorides, chloral hydrate cresols, epichlorohydrin, hydrozoic acid, isocyanates, methyl isocyanoacetate, phenols, phosphates, salicylic acid sodium salicylate, sodium peroxyborate, potassium bromate resorcinol, salicylic acid, strong oxidizers, sulfates, sulfites, taimin, tartrates, tinctures trinitrobenzoic acid, urea nitrate. On small fires, use dry chemical, Halori, or CO2 extinguishers. [Pg.9]

Choline Salicylate. 2-HydroxyS,N,N-trimethyl-ethanaminium salt with 2 hydroxybenzoic acid (1 1) (2-fiy-droxyethyl)trimethylammonium salicylate choline salicylic acid salt salicylic acid choline salt Actasal Arret Arthro-pan Artrobione Audax Mundisal. C.jHuNO, mol wt 241.28. C 59.73%, H 7.94%, N 5,81%, O 26.53%. Prepn from choline chloride and sodium salicylate Broh-Kahn, Intern. Rec. Med. 173, 219 (Apr. 1960) cf. Johnson, Brit, pat. 8031 (1919) Broh-Kahn et al., U.S, pat. 3,069,321 (1962 to Labs, for Pharmaceut. Dev,). Variations of process Bdg. pat. 583,513 (1960 to Mnndipharma, AG). [Pg.343]

Several salts of salicylic acid, sodium salicylate USP, choline salicylate USP, and magnesium salicylate USP, and... [Pg.1453]

Benzoic acid, 4-(((ethylphenylamino) methylene) amino)-, ethyl ester. See N-(p-Ethoxycarbonylphenyl)-N-ethyl-N-phenylformamidine Benzoic acid, 2-hydroxy-, 4-(1,1-dimethylethyl) phenyl ester. See p-t-Butylphenyl salicylate Benzoic acid nitrile. See Benzonitrile Benzoic acid sodium salt. See Sodium benzoate Benzoic acid, tetraester with 2,2-bis (hydroxymethyl)-1,3-propanediol Benzoic acid, tetraester with pentaerythritol. See Pentaerythrityl tetrabenzoate... [Pg.990]

See Isoamyl propionate Isopentyi pyruvate. See Isoamyl pyruvate Isopentyi salicylate. See Isoamyl salicylate Isopentyi valerate. See Isoamyl valerate Isopentyi xanthic acid, sodium salt. See Sodium isoamyl xanthate Isophenphos. See Isofenphos Isophorol, dihydro-. See Trimethylcyclohexanol Isophorone... [Pg.2241]

Lactic acid, alkyl fatty acids (salicylic acid, glycolic add, benzoic add Chlorhexidine gluconate/acetate Fatty alkyl 1,3-diaminopropane A-Fatty alkyl 3-aminopropionate, A-hydroxyethyl-A-carboxymethyl fatty acid sodium salt of amidoethylamine Ethyl alcohol, propyl alcohol, benzyl alcohol, pine oil Sodium hypochlorite (liquid chlorine bleach), chlorine dioxide, hypochlorous acid, trichloro- and dichloroisocyanuric acids and their salts, sodium perborate and activator, peroxy acid (per acid), magnesium salt of peroxy phthalic acid, oxygen bleach generated from ozone... [Pg.257]

When the phenol contains a carboxylic acid group, e.g., m- or p-hydroxy-benzoic acid, the acetylated derivative will of course remain in solution as the sodium salt, but is precipitated when the solution is subsequently acidified. Salicylic acid, however, cannot be acetylated under these conditions. [Pg.109]

Section 24 10 The Kolbe-Schmitt synthesis of salicylic acid is a vital step m the preparation of aspirin Phenols as their sodium salts undergo highly regioselective ortho carboxylation on treatment with carbon dioxide at elevated temperature and pressure... [Pg.1017]

Kolbe-Schmitt reaction (Section 24 10) The high pressure re action of the sodium salt of a phenol with carbon dioxide to give an o hydroxybenzoic acid The Kolbe-Schmitt reac tion IS used to prepare salicylic acid in the synthesis of as pinn... [Pg.1287]

A method of preparation is to react an acid salt of choline (such as choline chloride or choline bromide) with an alkaline salt of salicylic acid (such as sodium salicylate, potassium salicylate, or magnesium salicylate) in an alcoholic media. [Pg.334]

Perhaps the most widely known compound prepared from phenol is aspirin. If phenol, sodium hydroxide, and carbon dioxide are heated together under pressure, salicylic acid is formed (as the sodium salt) ... [Pg.346]

The acid itself (or the sodium salt) is a valuable drug in the treatment of arthritis. But the most widely known derivative of salicylic acid is aspirin, which has ihe following structure ... [Pg.346]

An additional useful test is to distil the acid or its sodium salt with soda lime. Heat 0.5 g. of the acid or its sodium salt with 0 2 g. of soda lime in an ignition tube to make certain that there is no explosion. Then grind together 0 5 g. of the acid with 3 g. of soda lime, place the mixture in a Pyrex test-tube and cover it with an equal bulk of soda hme. Fit a wide dehvery tube dipping into an empty test-tube. Clamp the tube near the mouth. Heat the soda lime first and then the mixture gradually to a dull-red heat. Examine the product this may consist of aromatic hydrocarbons or derivatives, e.g., phenol from salicylic acid, anisole firom anisic acid, toluene from toluic acid, etc. [Pg.777]

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