Sodium salicylates

C7H9N402- M.p. 337 C, an alkaloid obtained from cacao seeds or prepared synthetically. Constitutionally it is similar to caffeine, and is also a weak base. It is usually administered as the sodium compound combined with either sodium ethanoate or sodium salicylate, and is employed almost entirely as a diuretic. Physiologically theobromine resembles caffeine, but its effect on the central nervous system is less, while its action on the kidneys, is more pronounced. 

Sodium acetate CH3COONa Sodium succinate (CHaCOONa), Sodium benzoate CeHjCOONa Sodium formate HCOONa i Sodium oxalate fCOONa) J Sodium salicylate HOCeH COONa... 

Phenolic resins were the first totally synthetic plastics invented. They were commercialized by 1910 [I]. Their history begins before the development of the structural theory of chemistry and even before Kekule had his famous dreams of snakes biting their tails. It commences with Gerhardt s 1853 observations of insoluble resin formation while dehydrating sodium salicylate [2]. These were followed by similar reports on the behavior of salicylic acid derivatives under a variety of reaction conditions by Schroder et al. (1869), Baeyer (1872), Velden (1877), Doebner (1896 and 1898), Speyer (1897) and Baekeland (1909-1912) [3-17]. Many of these early reports appear to involve the formation of phenolic polyesters rather than the phenol-aldehyde resins that we think of today. For... 

Gaseous CO2 is extensively used to carbonate soft drinks and this use alone accounts for 20% of production. Other quasi-chemical applications are its use as a gas purge, as an inert protective gas for welding, and for the neutralization of caustic and alkaline waste waters. Small amounts are also used in the manufacture of sodium salicylate, basic lead carbonate ( white lead ), and various carbonates such as M2CO3 and M HC03 (M = Na, K, NH4, etc.). One of the most important uses of CO2 is to manufacture urea via ammonium carbamate ... 

Sodium Salicylate.—When an aldehyde is shaken with a saturated solution of sodium salicylate, there seems to be evidence of the formation of a weak molecular compound, and with cinnamic aldehyde well-defined crystals have been obtained which give on analysis —... 

A method of preparation is to react an acid salt of choline (such as choline chloride or choline bromide) with an alkaline salt of salicylic acid (such as sodium salicylate, potassium salicylate, or magnesium salicylate) in an alcoholic media. 

The salicylates include aspirin (acetylsalicylic acid) and related drugp, such as magnesium salicylate and sodium salicylate. The salicylates have analgesic (relieves pain), antipyretic (reduces elevated body temperature), and anti-inflammatory effects. All the salicylates are similar in pharmacologic activity however, aspirin has a greater anti-inflammatory effect than the other salicylates. Specific salicylates are listed in the Summary Drug Table Nonnarcotic Analgesics Salicylates and Nonsalicylates. 

Jurivich, D.A., Sistonen, L., Kroes, R.A., Morimoto, R.I. (1992). Effect of sodium salicylate on the human heat shock response. Science 255, 1243-1245. 

Actually, the reaction seems to be more complicated than this. At least part of the potassium p-hydroxybenzoate that forms comes from a rearrangement of initially formed potassium salicylate. Sodium salicylate does not rearrange. See Shine, FI.J. Ref. 402, p. 344. See also Ota, K. Bull. Chem. Soc. Jpn., 1974, 47, 2343. 

CjHjNaO, 113-24-6) see Flurbiprofen sodium salicylate see under salicylic acid sodium salt sodium 3-sulfobenzoate... 

Aspirin, sodium salicylate, choline magnesium trisalicylate, salsalate, diflunisal, salicylsalicylic acid, sulfasalazine, olsalazine... 

It has been reported that the percolation of conductance of water/AOT/n-heptane microemulsions is assisted by sodium cholate and retarded by sodium salicylate [282]. 

A significant contribution of rheo-NMR has been to show that the uniform shear-rate assumption may be violated in the case of certain classes of fluids in which pathological flow properties are exhibited. Figure 2.8.10 shows shear-rate maps [26] obtained for the wormlike surfactant system, cetylpyridinium chloride-sodium salicylate in water. While the velocity gradients show no deviation from uniformity at very low shear rates, above a certain critical value yc a dramatic variation in the rate-of-strain across the 7° cone gap is found. In particular a very high shear-rate band is found to exist at the mid-gap. 

Carbon dioxide gas is used to make urea (used as a fertiliser and in automobile systems and medicine), methanol, inorganic and organic carbonates, polyurethanes and sodium salicylate. Carbon dioxide is combined with epoxides to create plastics and polymers. 

The sorption of water vapor onto nonhydrating crystalline solids below RHq will depend on the polarity of the surface(s) and will be proportional to surface area. For example, water exhibits little tendency to sorb to nonpolar solids like carbon or polytetrafluorethylene (Teflon) [21], but it sorbs to a greater extent to more polar materials such as alkali halides [34-37] and organic salts like sodium salicylate [37]. Since water is only sorbed to the external surface of these substances, relatively small amounts (i.e., typically less than 1 mg/g) of water are sorbed compared with hydrates and amorphous materials that absorb water into their internal structures. 

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