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Related cancer risk

Due to the various sources of uncertainties associated with both groups of input data (dose and effect) needed for risk assessment, at present it is only possible to give an upper limit for the pure Rn-d related cancer risk. [Pg.441]

Rhodes, L.E., Shahbakhti, H., Azurdia, R.M. etal., Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers, Carcinogenesis, 24, 919, 2003. [Pg.335]

Costantino JP, Redmond CK, and Bearden A (1995) Occupationally related cancer risk among coke oven workers 30 years of follow up. Journal of Occupational Environmental Medicine 37 597-604. [Pg.637]

International Commission on Radiolr cal Protection (ICRP) (2006). Low-Dose Extrapolation of Radiation-Related Cancer Risk, Valentin, J., ed., ICRP Publication 99, Elsevier, Amsterdam, 141 pages. [Pg.679]

In additional EPA studies, subchronic inhalation was evaluated ia the rat for 4 and 13 weeks, respectively, and no adverse effects other than nasal irritation were noted. In the above-mentioned NTP chronic toxicity study ia mice, no chronic toxic effects other than those resulting from bronchial irritation were noted. There was no treatment-related increase ia tumors ia male mice, but female mice had a slight increase in bronchial tumors. Neither species had an increase in cancer. Naphthalene showed no biological activity in other chemical carcinogen tests, indicating Htde cancer risk (44). No incidents of chronic effects have been reported as a result of industrial exposure to naphthalene (28,41). [Pg.486]

Glutathione S-transferase M1 Deficient activity in about 50% of Caucasians. Carriers of the deficiency may have a slightly increased risk for a number of smoking-related cancers. [Pg.950]

An evaluation of the Health Professionals Follow-Up Study (Giovannucci et al., 1995) has detected a lower prostate cancer risk associated with the greater consumption of tomatoes and related food products. Tomatoes are the primary dietary source of lycopene and lycopene concentrations are highest in testis and adrenal tissue (Clinton, 1998). In paired benign and malignant prostate tissue from 25 American men, 53-74 yrs, undergoing... [Pg.121]

GIOVANNUCCI E, ASCHERIO A, RIMM E B, STAMPFER M J, COLDITZ G A and WILLETT W 0 (1995) Intake of carotenoids and retinol in relation to risk of prostate cancer. JNatl Cancer Inst. 87(23) 1767-76. [Pg.125]

Freudenheim, J.L. et al.. Premenopausal breast cancer risk and intake of vegetables, fruits, and related nutrients, J. Natl. Cancer Inst., 88, 340, 1996. [Pg.141]

A number of endocrine factors have been linked to the incidence of breast cancer.5,6 Many of these relate to the total duration of menstrual life. Early menarche (prior to age 12) and late menopause (after age 55) increase a women s breast cancer risk. Similarly, investigators have reported that bilateral oophorectomy prior to age 35 reduces the relative risk of developing breast cancer. Nulliparity and a late age at first birth (greater than or equal to 30 years) have been reported to increase the lifetime risk of developing breast cancer twofold. [Pg.1304]

The risk of colon cancer appears to be inversely related to calcium and folate intake. Calciums protective effect may be related to a reduction in mucosal cell proliferation rates or through its binding to bile salts in the intestine, whereas dietary folate helps in maintaining normal bowel mucosa. Additional micronutrient deficiencies have been demonstrated through several studies to increase colorectal cancer risk and include selenium, vitamin C, vitamin D, vitamin E, and 3-carotene however, the benefit of dietary supplementation does not appear to be substantial.11... [Pg.1343]

Whittemore AS, Harris R, Itnyre J, Collaborative Ovarian Cancer Group. Characteristics relating to ovarian cancer risk collaborative analysis of 12 US case-control studies. Am J Epidemiol 1992 136 1184-1203. [Pg.1395]

Mills, P. K., Beeson, W. L., Abbey, D. E., et al., Dietary habits and past medical history as related to fatal pancreas cancer risk among Adventists, Cancer, 61, 2578, 1988. [Pg.343]

Calculation of lung cancer risk for radon daughter exposure is based on factors developed by the National Council on Radiation Protection and Measurements (NCRP, 1984). The risk coefficients are expressed in terms of lifetime risk from lifetime exposure for a population of mixed ages, comparable to the standardized U.S. population, and range between one and two per 10,000 WLM of exposure. The percent increase in risk is related to a normal lifetime lung cancer risk of 0.041. [Pg.518]

Wright ME, Park Y, Subar AF, Freedman ND, Albanes D, Hollenbeck A, Leitzmann MF and Schatzkin A. 2008. Intakes of fruit, vegetables, and specific botanical groups in relation to lung cancer risk in the NIH-AARP Diet and Health Study. Am J Epidemiol 168(9) 1024-1034. [Pg.50]

Based on this concept of correlation between high replication rate/high persistent mutation risk, Pike et al. (1983) formulated the hypothesis of breast tissue age and developed a mathematical model to predict the effects of exposure to ovarian hormones. This model incorporates reproductive and endocrine items related to breast cancer and is able to predict the relative risk of individual situations with results that are very close to those observed in clinical trials. According to this hypothesis, both the years of exposure and the circulating serum levels of estrogens are associated to short-term breast cancer risk in postmenopausal women (Toniolo et al. 1995). [Pg.252]

At present, the only SERMs routinely used in clinical practice are tamoxifen and raloxifene. Tamoxifen is used essentially as adjuvant treatment in women with breast cancer. Its use is related to estrogenic effects on the uterus. Specifically, tamoxifen can be associated with an increase not only in endometrial hyperplasia and cancer risk but also in uterine leiomyoma dimensions and in a risk of developing active endometriotic lesions. [Pg.314]

Category C (possible human carcinogen) was evidenced by a dose-related increase in the incidence of leiomyosarcomas in the urinary bladder, a significant dose-related trend for combined hepatocellular adenomas and carcinomas in males, and a significantly higher incidence of combined lung adenomas and carcinomas in females. For the purpose of risk characterization, the RfD approach should be used for quantification of human cancer risk. The chronic exposure analysis revealed <100% RfD, and it is assumed that the chronic dietary endpoint is protective for cancer dietary exposure [64]. [Pg.94]

Animal product use among Adventists is strongly related to risk of fatal prostate cancer. [Pg.176]

Coffee use among Adventists is moderately related to risk of death from large bowel cancer in both sexes, as well as coronary disease and all causes in males. [Pg.176]

No data have been located relating to carcinogenicity in humans exposed to 1,4-dichlorobenzene via inhalation, orally, or dermally. Epidemiological studies which used occupational exposure data would be useful to elicit such information on human exposure and potential cancer risks to 1,4-dichlorobenzene. [Pg.162]

Boffetta P, Cardis E, Vainio H, et al. 1991. Cancer risks related to electricity production. European J Cancer 27(11) 1504-1519. [Pg.168]

The WHO considers in its drinking-water quality guidelines, in relation to genotoxic carcinogens, that a lifetime cancer risk for consumers of less than 10 represents a tolerable risk (WHO 1996). Guideline values associated with excess lifetime cancer risks of 10 and 10 are also presented for the genotoxic carcinogens to emphasize the fact that each country should select its own appropriate risk level. [Pg.305]


See other pages where Related cancer risk is mentioned: [Pg.235]    [Pg.235]    [Pg.14]    [Pg.117]    [Pg.118]    [Pg.123]    [Pg.129]    [Pg.27]    [Pg.54]    [Pg.28]    [Pg.224]    [Pg.338]    [Pg.17]    [Pg.511]    [Pg.1506]    [Pg.273]    [Pg.203]    [Pg.96]    [Pg.31]    [Pg.104]    [Pg.160]    [Pg.243]    [Pg.299]    [Pg.150]   
See also in sourсe #XX -- [ Pg.440 ]




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Cancer risk

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