Carcinogen, possible human

Probable human carcinogen Probable human carcinogen Possible human carcinogen Not classifiable as a human carcinogen... 

EXPOSURE GUIDELINES DFG TRK 0.03 ppm, animal carcinogen, possible human carcinogen. 

Carcinogenicity possible human carcinogen - lARC, anticipated human carcinogen - NTP ... 

The International Agency for Research on Cancer (lARC) has classified DEHP (44) as "an agent possibly carcinogenic to humans." However this classification is based only on the rodent studies and does not take into account the more recent understanding of the underlying mechanisms. 

Antimony tfioxide is currently designated as a possible human carcinogen by the International Agency for Research on Cancer (lARC) and ACGIH (31). However, a chronic inhalation study, conducted by the Antimony Oxide Industry Association (AOIA), found no evidence of carcinogenicity (31,32). 

Group 2B The agent (mixture) is possibly carcinogenic to humans. The exposure circumstance entails exposures that are possibly carcinogenic to humans. 

The formation of nitrosamines, e.g. n-nitrosodiedianolamine, which are possible human carcinogens, can occur in synthetic or semi-synthetic fluids which contain a nitrite salt and diethanolamine or triethanolamine. 

Carcinogenicity. No agreement exists over the carcinogenicity of MEK. One source believes MEK is a possible carcinogen in humans based on limited animal evidence. Other sources believe that there is insufficient evidence to make any statements about possible carcinogenicity. 

B- Possibly carcinogenic to humans Limited evidence on carcinogenicity in humans, and other relevant evidence missing occasionally a compound with insufficient human evidence but limited evidence on carcinogenicity in experimental animals... 

Dioxane is an impurity present in alcohol ethoxy sulfates formed during sulfation of the ethoxylated alcohol. 1,4-Dioxane is a carcinogen in rats and mice [312-314] and has been considered as a possible carcinogen to humans [315-317]. However, the no-effect dose in rats is equivalent to a daily intake of dioxane of 9.6-19.0 mg/kg/day, which corresponds to 0.672 g/day for humans. In other studies it has been determined that the threshold for onset of human toxicity of 1,4-dioxane lies above an intake of 76 mg/kg in adult males [318]. Although it seems to be demonstrated that amounts up to 1000 ppm of... 

The use of chlorine at such relatively high concentrations may give rise to the production of chlorinated by-products if the water supply contains traces of chemicals which can react with chlorine. Such trace chlorinated chemicals are known to be carcinogenic(4) and their presence in water supplies for possible human consumption should be minimised. 

It is important to note that for a particular substance the assumption of carcinogenicity to humans may be false, even though it is a proven carcinogen in several animal species. In such a case, the lower bound on the excess risk to humans is effectively zero, in the sense that zero-risk is a possibility which cannot be... 

The International Agency for Research on Cancer (IARC 1987) concluded that the evidence for carcinogenicity of lead and inorganic lead compounds was inadequate in humans and sufficient in animals. IARC (1987) classified lead and inorganic lead compounds in IARC Group 2B, possible human carcinogen. The Department of Health and Human Services (DHHS) has determined that lead acetate and phosphate may reasonably be anticipated to be carcinogens based on sufficient evidence from animal studies, but inadequate evidence from human studies (NTP 1994). 

Liver tumors developed in mice that were orally exposed to hexachloroethane for their whole lifetime. Tumors of this kind are common in mice. Hexachloroethane will not necessarily have the same effect on people. Male rats that were exposed to hexachloroethane for their lifetime developed kidney tumors. This type of tumor is not found in people, so it is unlikely that exposure to hexachloroethane would cause you to develop cancer of the kidney. The Department of Health and Human Services has determined that hexachloroethane may reasonably be anticipated to be a carcinogen (can cause cancer). The International Agency for Research on Cancer (IARC) has determined that hexachloroethane is not classifiable as to its carcinogenicity in people. EPA has determined that hexachloroethane is a possible human carcinogen. 

NTP determined that there was clear evidence of carcinogenicity in male rats based on the increased incidence of renal neoplasms and no evidence of carcinogenic activity in female rats (NTP 1989). The EPA classified hexachloroethane as a possible human carcinogen (Group C). The slope factor calculated by EPA is 1.4xl0 2 (mg/kg/day) 1 for both the oral and inhalation routes of exposure (IRIS 1995). IARC has determined that hexachloroethane is not classifiable as to human carcinogenicity (Group 3). 

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