Purple grape juice

You can try this yourself at home. You need some purple grape juice, blueberry juice, or the water left over after boiling a red cabbage. If you add clear distilled vinegar, the juice will turn red. If you add baking soda, the juice will turn blue. 

The consumption of a mixture of phenolic compounds presented in apple or purple grape juice inhibited mammary carcinogenesis in 7,12-dimethylbenzo[a]anthracene (DMBA) treated rats (Liu and others 2005 Jung and others 2006). However, the individual antioxidants of these foods studied in clinical trials, including (3-carotene, vitamin C, and vitamin E, do not appear to have consistent preventive effects comparable to the observed health benefits of diets rich in fruits and vegetables, suggesting that natural phytochemicals in fresh fruits and vegetables could be more effective than a dietary supplement. 

Jung KJ, Wallig MA and Singletary KW. 2006. Purple grape juice inhibits 7,12-dimethylbenz[a]anthracene (DMBA)-induced rat mammary tumorigenesis and in vivo DMBA-DNA adduct formation. Cancer Lett 233 279-288. 

Freedman and others (2001) determined the effects of purple grape juice and its main flavonoids on the functionality of platelets and the production of NO. They observed that incubation of platelets with diluted grape juice resulted in the inhibition of aggregation, increased production of NO, and decreased production of superoxide. To confirm the relevance of these findings, 20 healthy subjects were supplemented with 7 mL of black grape juice/kg/day for 14 days. The inhibition of platelet aggregation was also observed ex vivo there was an increase in the production of NO from 3.5 1.2 to 6.0 1.5 pmol/108 platelets and a decrease in the release of superoxide, from 29.5 5.0 to 19.2 3.1 arbitrary units. Under these conditions the antioxidant capacity of protein-free plasma increased by 50% (Freedman and others 2001). 

Stein JH, Keevil JG, Wiebe DA, Aeschlimann S and Folts JD. 1999. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 100 1050-1055. 

Recently, the possible synergistic interaction between flavonoids has been thoroughly discussed in connection with the cardioprotective effect of red wine and purple grape juice. 

It was postulated that the inhibition of LDL oxidation by red wine may help to explain the French paradox. Since Frankel and co-workers [73] showed that red wine inhibit the oxidation of LDL, several in vitro studies have confirmed this finding [26,74,75]. There is controversy over whether or not the consumption of red wine by humans reduces the oxidation of LDL ex vivo. While several studies found resistance of LDL oxidation after 2 weeks of red wine consumption in healthy subjects [75,76], others found no effect on the oxidation of LDL ex vivo [26,77]. Recently, Stein and coworkers [78] showed that short-term ingestion of purple grape juice (7.7 1.2 mL/Kg/day for 14 days) reduced the susceptibility to oxidation in coronary artery disease patients and that this is a potential mechanism by which flavonoids in purple grape products may prevent cardiovascular events, independent of alcohol content. 

Delphinidin-3-0-(6"-0-p-coumaroyl)glucoside Delphinidin-3-0-(6"-0-p-coumaroyl)-5-0-diglucoside Figure 1.20 Purple grape juice anthocyanins. 

For variety, try using some orange marmalade, raspberry or strawberry preserves, or even a tablespoon of frozen red or purple grape juice concentrate in place of sugar or other sweeteners. Combining the flavors of fruit with cocoa just can t be beat ... 

Purple grape juice and red wine Polyphenolic compounds Support normal, healthy cardiovascular function... 

Another option is to spread purple grape juice, over the paper (you can use a paint brush to do this). The message should appear in a different color/shade compared to the rest of the paper. This works because an acid in the grape juice reacts with the sodium bicarbonate that you used to write your message. 

S. R. Coimbra, S. FI. Lage, L. Brandizzi, V. Yoshida, P. L. da Luz (2005) The action of red wine and purple grape juice on vascular reactivity is independent of plasma lipids in hypercholester-olemic patients. Braz. J. Med Biol. Res., 38, 1339-1347. 

The beneficial effect of polyphenols on the endothelial function has also been observed for other dietary polyphenol-rich sources. Indeed, intake of purple grape juice has been shown to improve the endothelial function in hypercholesterolemic patients with impaired FMD similarly to red wine [102]. Moreover, purple grape juice intake improved FMD in teenagers with metabolic syndrome [98]. In addition, a grape-derived product has been shown to improve the impaired FMD in healthy subjects subsequent to the intake of a high-fat meal [77]. Similarly, intake of cocoa... 

Chou EJ, Keevil JG, Aeschlimann S, Wiebe DA, Folts JD, Stein JH (2001) Effect of ingestion of purple grape juice on endothelial function in patients with coronary heart disease. Am J Cardiol 88 553-555... 

The effect of the nonalcoholic components of red wine was also studied [101,102]. By using wine and alcohol-free red wine extract, it was shown that although the alcohol component of the wine may be important for a favorable lipid pattern, such potential health benefits may be independent of the proposed antioxidant effects of red wine [92,100,103,104], In a 2001 study it was shown that polyphenols in dealcoholized red wine can reduce in vivo lipid peroxidation, as measured by F2-isoprostanes, in smoking subjects, whereas no reduction in lipid peroxidation was observed after red or white wine consumption [102], In 2001 human intervention study [102], it was shown that alcohol-free red wine extract can inhibit LDL oxidation ex vivo. A short-term ingestion of purple grape juice reduced LDL susceptibility to oxidation in patients with coronary artery disease [105,106]. 

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