Pulmonary nodule

Pulmonary Interstitial fibrosis, pulmonary nodules, pleuritis, pleural effusions... 

Solitary pulmonary nodule Lung cancer (NSCLC) Esophageal cancer Colonrectal cancer... 

T. Mattfeldt, F. Liewald, S.N. Reske, B. Neumaier, 3-deoxy-3-[(18)F]fluorothymi-dine-positron emission tomography for noninvasive assessment of proliferation in pulmonary nodules, Cancer Res. 62(12) (2002) 3331-3334. 

A 73-year-old woman developed fever and cough 2 weeks after completing a third cycle of fludarabine for chronic lymphocytic leukemia. A chest X-ray showed multiple pulmonary nodules and a biopsy showed a mononuclear interstitial infiltrate without evidence of malignant, infectious, granulomatous, or vascular causes. Her symptoms and pulmonary nodules resolved after treatment with glucocorticoids (4). 

Garg S, Garg MS, Basmaji N. Multiple pulmonary nodules an unusual presentation of fludarabine pulmonary toxicity case report and review of hterature. Am J Hematol 2002 70(3) 241-5. 

Shah SP, Khine M, Anigbogu J, Miller A. Nodular amyloidosis of the lung from intravenous drug abuse an uncommon cause of multiple pulmonary nodules. South Med J 1998 91 (4) 402-404. 

Amyloid was not found in fhe skin biopsies of several of our patients with heroin related secondary amyloidosis, although interestingly, multiple pulmonary nodules due to AA amyloid have been described in an HIV positive intravenous drug abuser [31a]. 

Blankenberg FG, Mandl S, Cao YA et al (2004) Tumor imaging using a standardized radiolabelled adapter protein docked to vascular endothelial growth factor. J Nucl Med 45 1373-1380 Blum JE, Handmaker H, Rinne NA (1999) The utility of a somatostatin-type receptor binding peptide radiopharmaceutical (P829) in the evaluation of solitary pulmonary nodules. Chest... 

Tc-depreotide is valuable for scintigraphic imaging of solitary pulmonary nodules in combination with computer tomography (CT) or chest x-ray, in patients suspected of malignancy. 

In patients, specific uptake in single pulmonary nodules is seen 1.5-2 h postinjection, also in regional lymph nodes overexpressing somatostatin receptors. Lymphoreti-cular response affects initially hilar, mediastinal, supraclavicular and axillary nodes, extending to distant nodes and the spleen (Danielsson et al. 2005). 

Tumor size on day 18, numbers of pulmonary nodules and weight of lymph node on day 35. 

Vogt FM, Herborn CU, Hunold P, Lauenstein TC, Schroder T, Debatin JF, Barkhausen J (2004) HASTE MRI versus chest radiography in the detection of pulmonary nodules comparison with MDCT. AJR Am J Roentgenol 183 71-78... 

Pulmonary arteriovenous malformations are caused by abnormal communications between pulmonary arteries and pulmonary veins, which are most commonly congenital in nature [4, 20]. Although these lesions are uncommon, they are an important part of the differential diagnosis of common pulmonary problems such as hypoxemia and pulmonary nodules. These abnormal communications have been given various names including pulmonary arteriovenous fistulas, pulmonary telangiectases, and pulmonary arteriovenous malformations [20,66). 

For routine evaluation, it is generally sufficient to reconstruct 5 mm-thick slices with 4 mm increment, resulting in 20% overlap. Overlapping reconstruction is mandatory for adequate depiction of smaller structures (e.g., pulmonary nodules) between slices. Without overlapping reconstruction, smaller structures at the edge of a slice might be obscured by partial volume effects (see Figs. 14.4,14.5 and 14.6). 

Fig. 14.4. Two adjacent slices with 5-mm-slice thickness, 0% overlap-no pulmonary nodules are visible...

However, it is also mandatory to refer to the axial slices in order to report the para-cardial findings that may frequently be observed in CTA studies. These findings may include lymph node enlargement, pulmonary nodules and tumors (Horton et al. 2002), or even quite commonly esophageal hernias. These incidental findings should trigger an... 

A recent report (30) on the possible effect of CLA on metastasis demonstrated that CLA, at concentrations of 0.5-1%, had a significant effect on the latency, metastasis, and pulmonary tumor burden of transplantable murine mammary tumors grown in mice fed 20% fat diets. The latency of tumors from mice fed CLA was significantly increased compared with that of mice fed the 0% CLA control diet. The volume of pulmonary tumor burden that resulted from spontaneous metastasis, decreased in a dose-dependent manner. Tumors of mice fed as little as 0.1% CLA and as much as 1% had significantly decreased numbers of pulmonary nodules compared with mice fed diets containing no CLA. Dietary CLA (0.5 and 1%) also seemed more efficient in decreasing pulmonary tumor burden than the eicosanoid... 

Cronin P, Dwamena BA, Kelly AM et al. (2008) Solitary pulmonary nodules meta-analytic comparison of cross-sectional imaging modalities for diagnosis of malignancy. Radiology 246 772-782... 

Cann CE, Gamsu G, Birnberg FA, Webb WR (1982) Quantification of calcimn in solitary pulmonary nodules using single- and dual-energy CT. Radiology 145 493-496... 

Fig. 27.8. Neutropenic febrile patient who underwent autologous stem-cell transplantation due to non-Hodgkin lymphoma. At day 2 after transplantation, neutropenia and fever occurred. Therefore, antifungal treatment (Amphotericin B) was started. Ill-defined pulmonary nodules were diagnosed at day 7. Haematological reconstitution took place at day 13, si-...

Klein J8 et al. (1996) Transthoracic needle biopsy with a coaxially placed 20-G automated cutting needle results in 122 patients. Radiology 198 715-720 Laurent F et al. (2000) CT-guided transthoracic needle biopsy of pulmonary nodules smaller than 20 mm results with an automated 20-G coaxial cutting needle. Clin Radiol 55 281-287... 

Tomiyama N et al. (2000) CT-guided needle biopsy of small pulmonary nodules value of respiratory gating. Radiology 217 907-910... 

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