Significant effect

Graphitic corrosion is a slow corrosion process, typically requiring many years to effect significant damage. Complete penetration of thick cross sections has, however, occurred in as little as 2 years in adverse environments. On the other hand, cast iron components can be found in use in Europe after 160 years of service. Although graphitic corrosion causes a substantial reduction in mechanical strength, it is well known that corroded cast iron, when sufficiently supported, may remain serviceable when internal pressure is low and shock loads are not applied. 

ACE inhibitors are approved for the treatment of hypertension and cardiac failure [5]. For cardiac failure, many studies have demonstrated increased survival rates independently of the initial degree of failure. They effectively decrease work load of the heart as well as cardiac hypertrophy and relieve the patients symptoms. In contrast to previous assumptions, ACE inhibitors do not inhibit aldosterone production on a long-term scale sufficiently. Correspondingly, additional inhibition of aldosterone effects significantly reduces cardiac failure and increases survival even further in patients already receiving diuretics and ACE inhibitors. This can be achieved by coadministration of spironolactone, which inhibits binding of aldosterone to its receptor. 

The therapeutic ratio of antineoplastic agents, which is defined by the dose necessary to cause a significant anticancer effect divided by the dose effecting significant side effects, is generally low (near to one). 

The chain termination rate varies inversely with the viscosity of the polymerization medium because of the Trommsdorff Effect (i.e., the reduction of the macroradical mobility with increasing reaction viscosity). This effect significantly influences reaction rate[ ,2, 10]. 

Another parametric effect is the apparent dependence of the heat transfer coefficient on the physical size of the heat transfer surface. Figure 24, from Burki et al. (1993), graphically illustrates this parametric effect by showing that the effective heat transfer coefficient can vary by several hundred percent with different vertical lengths of the heat transfer surface, for circulating fluidized beds of approximately the same particle diameter and suspension density. This size effect significantly contributed to confusion in the technical community since experimental measurements by inves-... 

Petroleum products themselves are the source of the many components but do not adequately define total petroleum hydrocarbons. However, the composition of petroleum products assist in understanding the hydrocarbons that become environmental contaminants, but any ultimate exposure is also determined by how the product changes with use, by the nature of the release, and by the hydrocarbon s environmental fate. When petroleum products are released into the environment, changes occur that affect their potential effects significantly. Physical, chemical, and biological processes change the location and concentration of hydrocarbons at any particular site. 

The conditions with the worst response value can be derived from the estimated effects. The worst-case situation is that combination of factor levels resulting in the worst result, e.g., the lowest resolution. The worst-case conditions are set using only the effects significant at... 

If the pulse width is of the order of picoseconds or shorter, the terms with 1 0 have to be taken into account. In the case of plane waves, this effect (usually referred to as the SS effect) leads to a change in the shape of the temporal envelope and to the shift of the pulse peak with respect to the center of the moving coordinate system. Another effect significant for... 

Introduction into a DC plasma requires rather more care and attention owing to its inherent design features. As the hydride is being introduced into the plasma, it is necessary to provide a controlled sheath of argon to contain the hydride and direct it into the plasma. This chimney effect significantly improves the sensitivity for hydride-forming elements. This interface has also formed the basis of an introduction system for mercury vapour into an atomic-fluorescence spectrometer as described by Godden and Stockwell [12]. 

Hematological Effects. Significant effects on the hematological system are not usually observed in humans exposed to carbon tetrachloride by inhalation (Heimann and Ford 1941 Norwood et al. 

TCA Panic disorder OCD (GAD, PTSD) Onset worsening side-effects on initiation some long-term effects Significant overdose toxicity WeU-described... 

The effectiveness of both sonication and biodegradation is contaminant and concentration specific. Extensive treatability studies will be required to maximize process effectiveness. Significant technical issues wiU have to be addressed before the technology can be used in the field. 

Decrease in fetal body weight Adverse respiratory effects Significant increase in tumor necrosis factor for alveolar macrophages No deaths... 

In limited proteolysis, proteases such as pronase E hydrolyzed the 7S subunits of soy proteins more than the IIS subunits, resulting in enhanced protein solubility. Deamidation with relatively insignificant peptide bond hydrolysis that occurred during the germination of soybeans imparted to the storage protein improved solubility and emulsifying activity. On the other hand, the incorporation of phosphorus in soy proteins by the protein kinase cAMPdPK was too low to effect significant... 

Quantitative depth profiling using polyatomic MCs+ and MCs2+ ions instead of atomic ions M= ions is well established in surface analysis using SIMS. The MCs+ technique, which reduces matrix effects significantly, was proposed by Gao in 1988.100 The formation of MCs+ has been explained by the recombination of sputtered neutral atoms (M) with... 

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