Neural adhesion

Adcock, K. H., Brown, D. J., Shearer, M. C., Shewan, D., Schachner, M., Smith, G. M., Geller, H. M. and Fawcett, J. W. Axon behavior at Schwann cell-astrocyte boundaries manipulation of axonal signaling pathways and the neural adhesion molecule LI can enable axons to cross. Eur. /. Neurosci. 20 1425-1435, 2004. 

CS295 Gomez, M., M. Hernandez, B. Johansson, R. de Miguel, J. A. Ramos, and J. Femandez-Ruiz. Prenatal cannabinoid and gene expression for neural adhesion molecule LI in the fetal rat brain. Brain Res Dev 2003 147(1-2) 201-207. CS296 Amtmann, D., P. Weydt, K. L. Johnson, M. P. Jensen, and G. T. Carter. Survey of cannabis use in patients with amyotrophic lateral sclerosis. Am J Hosp Palliat Care 2004 21(2) 95-104. 

Mohajeri, M. H., Bartsch,U., Vanderputten, H., Sansig, G., Mucke, L., and Schachner, M., Neurite outgrowth on nonpermissive substrate in vitro is enhanced by ectopic expression of the neural adhesion molecule LI by mouse astrocytes, Em J. Neurosci.,... 

Gdmez M, Hernandez ML, Johansson B, de Miguel R, Ramos JA, Ferndndez-Ruiz J (2003) Prenatal cannabinoid exposure and gene expression for neural adhesion molecule Ll in the fetal rat brain. Brain Res Dev Brain Res 147 201-207... 

Molenaar WM, Muntinghe FL. Expression of neural adhesion molecules and neurofilament protein isofotms in skeletal muscle tumors. Hum Pathol. 1998 29 1290-1293. 

Drosophila neuroglian - a member of the immunoglobulin superfamily with extensive homology to the vertebrate neural adhesion molecule LI. Cell 59 447-460. 

TGF l and TGF/32 enhance the glia-mediated stimulation of neurite outgrowth of dorsal root ganglion cells due to expression of the neural adhesion molecule LI (Saad et al., 1991), an effect that is mediated via stimulated NGF production in immature astrocytes. On the other hand, Flanders et al. (1991) reported a decrease in survival of embryonic chick ciliary ganglion cells, when TGF/32 and 3 were added to the cultured... 

Schachner, M. (1989) Families of neural adhesion molecules. Ciba Found. Symp. 145 156-169. 

Lai, C. Gore, M. Lemke, G. Structure, expression, and activity of Tyro 3, a neural adhesion-related receptor tyrosine kinase. Oncogene, 9, 2567-2578 (1994)... 

Abbreviations TF = transcription factor — =has role in LRR = leucine-rich-repeat GPCR = G-protein-coupled receptor NCAM = neural adhesion molecule ... 

Chromogranin A belongs to a family of acidic secretory proteins associated with dense core granules in a variety of endocrine and neuroendocrine cells (41). A lymphocyte surface marker, Leu7/NHK, cross-reacts with related epitope on the plasma membrane of PNEC and NEB (42). The other NEB cell surface markers include neural adhesion molecule (NCAM) and related epitope MOC-1, originally identified in the small cell lung carcinoma cell line (43,44). 

Kadmon, G., Kowitz, A., Altevogt, P., Schachner, M. Functional cooperation between the neural adhesion molecules LI and N-CAM is carbohydrate dependent. J. Cell Biol, 1990, 110, 209-218. 

Johnson, P. W. Abramow-Newerly, W. Seilheimer, B. Sadoul, R. Tropak, M. B. Arquint, M. Dunn, R. J. Schachner, M. Roder, J. C. Recombinant myelin-associated glycoprotein confers neural adhesion and neurite outgrowth function. Neuron 1989, 3 377-385. 

Lewandowska K, Balachander N, Sukenik C N and Culp L A 1989 Modulation of fibroneotin adhesive funotions for fibroblasts and neural sells by ohemioally derivatized substrates J. Cell Physiol. 141 334-45... 

Allen, K.W., Greenwood, L. and Wake, W.C., The stability of adhesive bonding between silicone mbber and alumina for neural prostheses. J. Adhes., 16(1), 61-76 (1983). 

Tardieu M, Hery C, Peudenier S, Boespflug O, Montagnier L (1992) Human immunodeficiency virus type 1-infected monocytic cells can destroy human neural cells after cell-to-cell adhesion. Ann Neurol 32(1) 11-17... 

Jung H, Toth PT, White PA, Miller RJ (2008) Monocyte chemoattractant protein-1 functions as a neuromodulator in dorsal root ganglia neurons. J Neurochem 104 254-263 Kahn L, Alonso G, Normand E, Manzoni OJ (2005) Repeated morphine treatment alters polysia-lylated neural cell adhesion molecule, glutamate decarboxylase-67 expression and ceU proliferation in the adult rat hippocampus. Em J Nemosci 21 493-500 Kaul M, Ma Q, Medders KE, Desai MK, Lipton SA (2007) HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death Differ (2) 296-305... 

NAP-I, NAP-2 Neutrophilactivating peptides -1 and -2 NBT Nitro-blue tetrazolium NCI Non-collagen 1 N-CAM Neural cell adhesion molecule... 

NF-xB Nuclear fector-xB NgCAM Neural-glial cell adhesion molecule... 

Fig. 4.6(a) Migration of LHRH neurocrine cells prenatal transportation along the track of extra-bulbar VN axons (caudal branch). CB, cribriform plate FB, forebrain cell types, TAG-1, transient axonal surface glycoprotein and N-CAM, neural cell adhesion molecule (from Yoshida et al, 1995). 

Schwanzel-Fukuda M., Reinhard G.R., Abraham S., Crossin K.L., et al. (1994). Antibody to neural cell adhesion molecule can disrupt the migration of luteinizing hormone-releasing hormone neurons into the mouse brain. J Comp Neurol 342, 174-185. 

Yoshihara Y Kawasaki M., Tamada A., Fujita H., et al. (1997). OCAM a new member of the neural cell adhesion molecule family related to zone-to-zone projection of olfactory and vomeronasal axons. J Neurosci 17, 5830-5842. 

Jones, F. S., Prediger, E. A., Bittner, D. A., DeRobertis, E. M., and Edelman, G. M. (1992b). Cell adhesion molecules as targets for Hox genes neural cell adhesion molecule promoter activity is modulated by cotransfection with Hox-2.5 and -2.4. Proc. Natl. Acad. Sci. USA 89 2086-2090. 

Regan CM. 1993. Neural cell adhesion molecules, neuronal development and lead toxicity. Neurotoxicology 14 69-74. 

Wu Q, Maniatis T. A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 1999 97[6] 779-790. 

Many transmembrane proteins that mediate intracellular signaling form complexes with both intra- and extracellular proteins. For example, neural cell adhesion molecules (NCAMs) are cell-surface glycoproteins (Ch. 7). The extracellular domains of NCAMs can activate fibroblast growth factor receptors when clustered by reaction with NCAM antibodies [4] or by homotypic binding to domains of adjacent cells (see Fig. 7-2). Activation was found to sequester a complex of NCAM, (31 spectrin and PKC(32 into rafts, as defined by the operational criteria discussed on p. 28. 

Leshchynska, I., Sytnyk, V., Morrow, J. S. and Schachner, M. Neural cell adhesion molecule (NCAM) association with PKCP2 via pi spectrin is implicated in NCAM-mediated neurite outgrowth. /. Cell Biol. 161 625-639, 2003. 

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