Fibroblast growth factors receptors

Achondroplasia (MIM 100800) Mutations in the gene encoding the fibroblast growth factor receptor 3... 

THE MOLECULAR BASES OF THE CHONDRODYSPLASIAS INCLUDE MUTATIONS IN GENES ENCODING TYPE II COLLAGEN FIBROBLAST GROWTH FACTOR RECEPTORS... 

Burke D et al Fibroblast growth factor receptors lessons from the genes. Trends Biochem Sci 1998 23 59. 

Many transmembrane proteins that mediate intracellular signaling form complexes with both intra- and extracellular proteins. For example, neural cell adhesion molecules (NCAMs) are cell-surface glycoproteins (Ch. 7). The extracellular domains of NCAMs can activate fibroblast growth factor receptors when clustered by reaction with NCAM antibodies [4] or by homotypic binding to domains of adjacent cells (see Fig. 7-2). Activation was found to sequester a complex of NCAM, (31 spectrin and PKC(32 into rafts, as defined by the operational criteria discussed on p. 28. 

COX (i) cyclooxygenase (ii) cytochrome oxidase FGFR fibroblast growth factor receptor... 

Epidermal growth factor receptor (EGFR) Fibroblast growth factor receptor (FGFR) Vascular endothelial growth factor receptor (VEGFR)... 

Qing, K., C. Mah, I Hansen, S. Zhou, V. Dwarki, and A. Srivastava, Human fibroblast growth factor receptor 1 is a co-receptor for infection by adeno-associated virus 2. Nat Med, 1999. 5(1) 71-7. 

Rao GA, Tsai R, Roura D et al (2008) Evaluation of the transfection property of a peptide ligand for the fibroblast growth factor receptor as part of PEGylated polyethylenimine polyplex. J Drug Target 16 79-89... 

J. Doukas, D. K. Hoganson, M. Ong, W. Ying, D. L. Lacey, A. Baird, G. F. Pierce, and B. A. Sosnowski, Retargeted delivery of adenoviral vectors through fibroblast growth factor receptors involves unique cellular pathways, FASEB J. 13 1459 (1999). 

The reason(s) observed in our studies for the preferential transduction of the proximal tubule and intercalated cells is not entirely clear. Several possible mechanisms may be implicated. The early steps of AAV infection involve attachment to a variety of cell surface receptors (heparan sulfate proteoglycan, fibroblast growth factor receptor, and av-/ 5 integrin) followed by a clathrin-dependent... 

Takami, K., Matsuo, A., Terai, K., Walker, D. G., McGeer, E. G. and McGeer, P. L. (1998). Fibroblast growth factor receptor-1 expression in the cortex and hippocampus in Alzheimer s disease. Brain Res. 802, 89-97. 

Agrotis A, Kanellakis P Kostolias G, et al, Proliferation of neointimal smooth muscle cells after arterial injury dependency on interaction between fibroblast growth factor receptor-2 and fibroblast growth factor-9. J Biol Chem 2004 [EPub ahead of print],... 

Hamada T, Suda N and Takayuki K (1999) Immunohistochemical localization of fibroblast growth factor receptors in the rat mandibular condylar cartilage and tibial cartilage. J. Bone Mine, r Metab. 17 274-282. 

C5. Carstens, R. P., Eaton, J. V., Krigman, H. R., Walther, P. J., and Garcia-Bianco, M. A., Alternative splicing of fibroblast growth factor receptor 2 (FGF-R-2) in human prostate cancer. Oncogene 15, 3059-3065 (1997). 

F4. Feng, S., Wang, F., Matsubara, A., Kan, M., and McKeehan, W. L., Fibroblast growth factor receptor-2 limits and receptor-1 accelerates tumorigenicity of prostate epithelial cells. Cancer... 

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