Luteinizing hormone releasing factor

CN 6-D-tryptophan-9-(Af-ethyl-L-prolinamide)-10-deglycinamide luteinizing hormone-releasing factor (pig)... 

Henderson SR, Baker C, Fink G (1977) Oestradiol-17beta and pituitary responsiveness to luteinizing hormone releasing factor in the rat a study using rectangular pulses of oestradiol-17 beta monitored by non-chromatographic radioimmunoassay. J Endocrinol 73 441-453... 

Sarkar DK, Fink G (1980) Luteinizing hormone releasing factor in pituitary stalk plasma from long-term ovariectomized rats effects of steroids. J Endocrinol 86 511— 524... 

Speight A, Popkin R, Watts AG, Fink G (1981) Oestradiol-17/3 increases pituitary responsiveness by a mechanism that involves the release and the priming effect of luteinizing hormone releasing factor. J Endocrinol 88 301-308... 

The conjugation of vitamin B12 has been shown to increase oral bioavailability of peptides, proteins, and particles.44 46 62,63 Russsell-Jones and coworkers have attempted to exploit RME of vitamin B12 for the enhanced intestinal uptake of macromolecules such as luteinizing hormone—releasing factor (LHRH), granulocyte colony-stimulating factor, erythropoietin, and a-interferon.44,46,63 Also, they demonstrated that surface modification of nanoparticles with vitamin B12 can increase their intestinal uptake.44,62 The extended applications of this unique transport system, however, appear partially hampered by its limited uptake capacity. In human being, the uptake of vitamin B12 is only 1 nmol per intestinal passage. 

Physiological aspects of luteinizing hormone releasing factor and sex steroid actions the interrelationship of agonist and antagonist... 

LIU305 CAS 34973-08-5 HR 3 LUTEINIZING HORMONE-RELEASING FACTOR (PIG), ACETATE (SALT)... 

The first 34 residues of human parathyroid hormone (PTH) [190] were identified from the Cl mass spectra of their phenylthiohydantoin derivatives by repeated Edman degradations on a Beckmann Sequencer [163]. In a similar way as part of the characterisation of ovine hypothalmic luteinizing hormone-releasing factor (LRF), the trimethylsilyi derivatives of the phenylthiohydantoins from Edman degradation were confirmed by MS [191]. 

One of the few potential successfiil sustained-release lipid formulations of biomacromolecules is the Depofoam concept by SkyePharma. It is different from the conventional liposomes by the increased surface area available, which makes the aqueous volume larger (122). It has been shown to successfiilly encapsulate (60-85%) and sustain the release of insulin, luteinizing hormone-releasing factor and others (123). 

C Data of Deslauriers et al, 1973b. Proton decoupled, natural abundance 13C FTnmr spectra obtained on a Varian LX-100-15 spectrometer at 2516 MHz on LRF (luteinizing hormone-releasing factor) at pH = 4-0. Chemical shifts obtained relative to TMS in a coaxial tube. 

Reid, R.L., G.R. Leopold S.S.C. Yen. 1981. Induction of ovulation and pregnancy with pulsatile luteinizing hormone-releasing factor dosage and mode of delivery. Fertil. Steril. 36 553-9. 

M14. Moss, R. L., and McCann, S. M., Induction of mating behaviour in rats by luteinizing hormone releasing factor. Science 181, 177-179 (1973). 

R. Burgus, M. Butcher, M. Amoss, N. Ling, M. Monahan, J. River, P. Fellows, R. Blackwell, W. Vale, R. GuiUemin, Primary structure of the ovine hypothalamic luteinizing hormone releasing factor (LRF) Proc. Natl. Acad. Sci. USA 69 278-282 (1972)... 

Luteinizing hormone-releasing factor. In 1959 we began an intensive search for a possible LH-releasing action of hypothalamic extracts and employed a new sensitive and specific assay for LH, the ovarian ascorbic acid depletion test of Parlow (1). In immature female rats which have been pretreated with gonadotrophins, minute doses of LH evoke a decline in ovarian ascorbic acid concentration. Other anterior lobe hormones are without effect. 

---