Monocyte-derived dendritic cell

DC, dendritic cell EC, endothelial cell EpC, epithelial cell FDC, follicular dendritic cell FDL, foot draining lymph FLS, fibroblast-like synoviocyte MC, mast cell MDDC, monocyte-derived dendritic cell MLS, macrophage-like synoviocyte MNC, mononuclear cell Mo, monocyte M0, macrophage OB, osteoblast pDC, plasmacytoid dendritic cell PMNs, polymorphonuclear neutrophils SC, stromal cell STC, synovium tissue cell TB, trabecular bone. 

Humrich JY, Humrich JH, Averbeck M, et al. Mature monocyte-derived dendritic cells respond more strongly to CCL19 than to CXCL12 consequences for directional migration. Immunology 2006 117(2) 238-247. 

Yoshida M, Babensee JE (2004) Polydactic-co-glycolic acid) enhances maturation of human monocyte-derived dendritic cells. J Biomed Mater Res 71 45-54... 

Coutant, K.D. et al., Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen, Toxicol. Sci., 52, 189, 1999. 

Aiba, S. et al, In vitro treatment of human transforming growth factor-betal-treated monocyte-derived dendritic cells with haptens can induce the phenotypic and functional changes similar to epidermal Langerhans cells in the initiation phase of allergic contact sensitivity reaction, Immunology, 101, 68, 2000. 

Histamine induces intracellular Ca " flux, actin polymerization, and chemotaxis in immature DCs due to stimulation of HRl and HR3 subtypes. Maturation of DCs results in loss of these responses. In maturing DCs, however, histamine dose-dependently enhances intracellular cAMP levels and stimulates IL-10 secretion, while inhibiting production of IL-12 via HR2 [16]. Interestingly, although human monocyte-derived dendritic cells have both histamine Hj and H2 receptors and can induce CD86 expression by histamine, human epidermal Langerhans cells express neither H nor Hj receptors [72]. 

Idzko M, la Sala A, Ferrari D, Panther E, Herouy Y, Dichmann S, et al Expression and function of histamine receptors in human monocyte-derived dendritic cells. J Allergy Clin Immunol 2002 109 839-846. 

Hammad H, Charbonnier AS, Duez C, Jacquet A, Stewart GA, Tonnel AB, Pestel J Th2 polarization by Der p 1 pulsed monocyte-derived dendritic cells is due to the allergic status of the donors. Blood 2001 98 1135-1141. 

De Smedt, A.C., Van Den Heuvel, R.L., Van Tendeloo, V.F., Berneman, Z.N., Schoeters, G.E., Weber, E. and Tuschl, H. (2002) Phenotypic alterations and 11-1 neta production in CD34( +) progenitor- and monocyte-derived dendritic cells after exposure to allergens a comparative analysis. Archives of Dermatological Research, 294, 109-116. 

Chen LY, Lin YL, Chiang BL. Levamisole enhances immune response by affecting the activation and maturation of human monocyte-derived dendritic cells. Clin Exp Immunol 2008 151(1) 174-81. 

Thurner, B., I. Haendle, C. Roder, et al.. Vaccination with mage-3 Al peptide-pulsed mature, monocyte-derived dendritic cells expands specific cytotoxic T cells and induces regression of some metastases in advanced stage IV melanoma. J Exp Med, 1999.190(11) 1669-78. 

Drury AN, Szent-Gyorgyi A (1929) The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart. J Physiol 68(3) 213—237 Englert M, Quitterer U, Klotz K-N (2002) Effector coupling of stably transfected human A3 adenosine receptors in CHO cells. Biochem Pharmacol 64(l) 69-73 Fossetta J, Jackson J, Deno G, Fan X, Du XK, Bober L, Soude-Bermejo A, de Bouteiller O, Caux C, Lunn C, Lundell D, Palmer RK (2003) Pharmacological analysis of calcium responses mediated by the human A, adenosine receptor in monocyte-derived dendritic cells and recombinant cells. Mol Pharmacol 63(2) 342-350... 

Ammon C, Meyer SP, Schwarzfischer L, Krause SW, Andreesen R, Kreutz M. Comparative analysis of integrin expression on monocyte-derived macrophages and monocyte-derived dendritic cells. Immunology 2000, 100, 364—369. 

L3. Lapteva, N., Ando, Y., Nieda, M., Hohjoh, H., Okai, M., Kikuchi, A., Dymshits, G., Ishikawa, Y., Juji, T., and Tokunaga, K., Profihng of genes expressed in human monocytes and monocyte-derived dendritic cells using cDNA expression array. Br. J. Haematol. 114, 191-197 (2001). L4. Lauw, F. N., Dekkers, P. E., te Velde, A. A., Speelman, P., Levi, M., Kurimoto, M., Hack, C. E., van Deventer, S. J., and van der Poll, T., Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. J. Infect. Dis. 179,646-652 (1999). 

IFN-a belongs to the type I IFNs. Type I IFNs have the ability to promote the survival and differentiation of antigen-activated T helper cells (M8, A5, S17, B18). They also promote maturation of monocyte-derived dendritic cells (S1). Thus type I IFNs might play a central role in initiating the immune response to antigens (R12). 

Santini, S. M., Lapenta, C., Logozzi, M., Parlato, S., Spada, M., et al., Type I interferon as a powerful adjuvant for monocyte-derived dendritic cell development and activity in vitro and in Hu-PBL-SCID mice. J. Exp. Med. 191, 1777-1788 (2000). 

Nakahara, T., Uchi, H., Urabe, K., Chen, Q., Furure, M., and Moroi, Y. 2004. Role of c-Jun N-terminal kinase on lipopolysaccharide induced maturation of human monocyte-derived dendritic cells. Int Immunol 16 1701-1709. 

Skorokhod OA, Alessio M, Mordmuller B, Arese P, Schwarzer E. Hemozoin (malarial pigment) inhibits differentiation and maturation of human monocyte-derived dendritic cells a peroxisome proliferator-activated receptor-gamma-mediated effect. J. Immunol. 2004 173 4066-4074. 

Wiesemann E, Sonmez D, Heidenreich F, Windhagen A (2002) Interferon-beta increases the stimulatory capacity of monocyte-derived dendritic cells to induce lL-13, lL-5 and lL-10 in autologous T-cells. J Neuroimmunol 123 160-169. 

Histamine induces CD86 expression and chemokine production in immature human derived monocyte-derived dendritic cells that can be blocked by diphenhydramine and other HI receptor antagonists. 

Piemonti, L. et al. (2000) Vitamin D3 affects differentiation, maturation, and function of human monocyte-derived dendritic cells. Journal of Immunology, 164, 4443-4451. 

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