Macrophage human monocyte-derived

Yeh MW, Kaul M, Zheng J, Nottet HS, Thylin M, Gendelman HE, Lipton SA (2000) Cytokine-stimulated, but not HIV-infected, human monocyte-derived macrophages produce neurotoxic levels of 1 -cysteine. J Immunol 164(8) 4265-4270... 

Von Eckardstein, A, Langer, C, Engel, T, Schaukal, I, Cignarella, A, Reinhardt, J, Lorkowski, S, Li, Z, Zhou, X, Cullen, P, and Assmann, G, 2001. ATP binding cassette transporter ABCA1 modulates the secretion of apolipoprotein E from human monocyte-derived macrophages. FASEB J 15, 1555-1561. 

It was found that the HIV envelope glycoprotein in vitro increases the production of NO by human monocyte-derived macrophages [114]. NO production is increased in patients who have AIDS [115], and the increased concentrations of nitrite in AIDS patients with opportunistic infections is caused by T gondii, Pneumocystis carinii, Mycobacterium tuberculosis, and Mycobacterium avium, whereas nitrite concentrations are normal in symptom-free patients. It was also confirmed that there was increased production of NO in the sera of children with HIV-1 infection, and of circulating cytokines, such as interleukin lp, tumor necrosis factor a, and interferon y. It is postulated that rises in the concentrations of these cytokines may represent a substantial stimulation of NO production [116]. In contrast, it has been shown that there was no altered endogenous nitrate formation in eight patients with AIDS, most of whom had opportunistic infections [117]. It has also been noted that there were high... 

Snijder, M. L., Polacek, D., Scanu. A. M., and Fless, G. M., Comparative binding and degradation of lipoprotein(a) and low density lipoprotein by human monocyte-derived macrophages. J. Biol. Chem. 267, 339-346 (1992). 

Porter AE, Gass M, Muller K, Skepper JN, Midgley P, Welland M (2007) Visualizing the uptake of C60 to the cytoplasm and nucleus of human monocyte-derived macrophage cells using energy-filtered transmission electron microscopy and electron tomography. Environ. Sci. Technol. 41 3012-3017. 

Nicholson, A.C., Friede, S., Pearce, A., and SUverstein, R.L., 1995, Oxidized LDL binds to CD36 on human monocyte-derived macrophages and transfected ceU Unes Evidence implicating the lipid moiety of the lipoprotein as the binding Aie.,Arterioscl. Tromb. Vase. Biol. 15 269-275. 

Anthonsen, M.W., Stengel, D., Hourton, D., Ninio, E., Johansen, B., 2000, Mildly oxidized LDL induces expression of group 11a secretory phospholipase A(2) in human monocyte-derived macrophages, Arterioscler Thromb Vase Biol, 20 1276-1282. 

Asmis, R., Wintergerst, E.S., 1998, Dehydroascorbic add prevents apoptosis induced by oxidized low-density lipoprotein in human monocyte-derived macrophages, Eur. J. Biochem. 255 147-155. 

K. Hirano, S. Yamashita, Y. Nakagawa, T. Ohya, F. Matsuura, T. Tsukamoto, Y. Okamoto, A. Matsuyama, K. Matsumoto, J. Miyagawa and Y. Matsuzawa, Expression of human scavenger receptor class B type I in cultured human monocyte-derived macrophages and atherosclerotic lesions, Circ. Res. 85 (1999) 108-116. 

We have demonstrated that human monocyte derived macrophages (HMDMs) isolated from NIDDM patients after consumption of PJ for 3 months, the carotid lesion derived after endartherectomy from CAS patients that consumed PJ (Figure 8.4A), and also mouse peritoneal macrophages (MPMs) isolated from E° mice after consumption of PJ concentrate (12.5 pL/mouse/day, equivalent to 0.35 pmol of total... 

C6. Chait, A., Iverius, P.-H., and Brunzell, J. D., Lipoprotein lipase secretion by human monocyte-derived macrophages. J. Clin. Invest. 69, 490—493 (1982). 

Clriamgi A, CalvairiM, Meli E, Traggiai E, Moroiri F(2001) Synthesis aird release of neurotoxic kyirui eirine metabolites by human monocyte-derived macrophages. J Neuroimmunol 120 190-198. 

Devaraj, S., Hugou, 1., and Jialal, I. (2001) Alpha-tocopheroi decreases CD36 expression in human monocyte-derived macrophages. J Lipid Res 42, 521-7. 

Newman, S.L., Henson, J.E. and Henson, P.M, (1982). Phagocytosis of senescent neutrophils by human monocyte-derived macrophages and rabbit inflammatory macrophages. J. Exp. Med. 156, 430-442. 

Smythies LE, White CR, Maheshwari A, Palgunachari MN, Anantharamaiah GM, Chaddha M, Knnmdkar AR, Datta G (2010) Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages. Am J Physiol Cell Physiol 298 C1538-C1548... 

Drazek, E. S., Houng, H.-S.H., Crawford, R.M., Hadfield, T.L., Hover, D.L., Warren, R. 1995. Deletion of purE attenuates Brucella melitensis 16M for growth in human monocyte-derived macrophages. Infect. Immun. 63 3297-3301. 

The j8-VLDL receptor has been identified on mouse peritoneal macrophages [13,14], foam cells associated with rabbit aortic atherosclerotic plaques [58], and human monocyte-derived macrophages [14]. Although )8-VLDL can bind to LDL receptors, LDL do not compete with I-labeled jS-VLDL for uptake by mouse peritoneal macrophages [13,14], In addition, monocytes from LDL receptor-negative FH patients or from normal subjects express equivalent numbers of j8-VLDL receptors [14]. The j8-VLDL receptors thus are distinct from LDL receptors. The -VLDL receptor is also distinct from the receptors for chemically modified lipoproteins (see below). 

Phagocytosis of apoptotic cells by macrophages leads to the production of anti-inflammatory cytokines as a way of preventing inflammation. Kurosaka et al. [79] have demonstrated that human serum potentiates the production of two anti-inflammatory cytokines, IL-10 and TGF-J3, by both TPA-treated THP-1 cells and human monocyte-derived macrophages. This enhanced response to the presence of apoptotic cells also results in the suppression of the production of the pro-inflammatory cytokine IL-8. In addition, human IgG and FcyRI appear to be critical in triggering the production of anti-inflammatory cytokines by macrophages in response to apoptotic cells. 

Remold, H. G., Mednis, A., Hein, A. and Caulfield, J. P. (1988) Human monocyte-derived macrophages are lysed by schistosomula of Schistosoma mansoni and fail to kill the parasite after activation with interferon gamma. Am. J. Pathol. 131 146-155. 

Pietraforte, D., Tritarelli, E., Testa, V., and Minetti, M. (1994). gpl20 HIV envelope glycoprotein increases the production of nitric oxide in human monocyte-derived macrophages. J. Leukocyte Biol. 55, 175-182. 

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