Isoamyl amine

On the other hand, Nishimura and colleagues (374) obtained isobutyl amine and isoamyl amine from male mouse urine responsible for female puberty acceleration. 

Bibutylamin 4, 157,1371, II 633. Di-sek.-butyl-amin 4,162, U 636. Diisobutylamin 4, 166, 1374, II638. Propyl-[x-methyl butyl]-amin 4,178. Isopropyl-[a./ -dunethyl-ptopyl]-amin 4,180. Methyl-athyl-iBoamyl-amin 4,181. Propyl-isoamyl-amin 4,182,1381. 

Take et al studied the infrared spectra of amines adsorbed on montmorillonite pillared with AI2O3 or Z1O2 and calcined at 723 K. From the intensities of the bands due to adsorbed pyridine, the number of Bronsted and Lewis acid sites on the AI2O3 — pillared montmorillonite were estimated to be 0.36 and 0.93 mmol g", respectively, and those on the Zr02 pillared material to be 0.32 and 0.92 mmol g , respectively. Competitive adsorption of pyridine and isoamyl amine revealed that about 30 percent of Brensted acid sites was located on the external surface of the pillared montmorillonites. 

Description of Sample The sample of spectrum 16-A was obtained as a low-boiling liquid by-product, IV (11% yield), of the pyrolysis of methyl w-propyl isoamyl amine oxide (I). Other products from the pyrolysis were propylene (II) and isoamylene (III). Molecular weight data obtained on the unknown gave a value of 70, which among other things indicated that the sample was unlikely to contain nitrogen. 

If an aliphatic amino group is to a COOR, CN, CHO, COR, and so on, and has an a hydrogen, treatment with nitrous acid gives not a diazonium salt, but a diazo compound Such diazo compounds can also be prepared, often more conveniently, by treatment of the substrate with isoamyl nitrite and a small amount of acid. Certain heterocyclic amines also give diazo compounds rather than diazonium salts. ... 

Electrophilic substitution of the ring hydrogen atom in 1,3,4-oxadiazoles is uncommon. In contrast, several reactions of electrophiles with C-linked substituents of 1,3,4-oxadiazole have been reported. 2,5-Diaryl-l,3,4-oxadiazoles are bromi-nated and nitrated on aryl substituents. Oxidation of 2,5-ditolyl-l,3,4-oxadiazole afforded the corresponding dialdehydes or dicarboxylic acids. 2-Methyl-5-phenyl-l,3,4-oxadiazole treated with butyllithium and then with isoamyl nitrite yielded the oxime of 5-phenyl-l,3,4-oxadiazol-2-carbaldehyde. 2-Chloromethyl-5-phenyl-l,3,4-oxadiazole under the action of sulfur and methyl iodide followed by amines affords the respective thioamides. 2-Chloromethyl-5-methyl-l,3,4-oxadia-zole and triethyl phosphite gave a product, which underwent a Wittig reation with aromatic aldehydes to form alkenes. Alkyl l,3,4-oxadiazole-2-carboxylates undergo typical reactions with ammonia, amines, and hydrazines to afford amides or hydrazides. It has been shown that 5-amino-l,3,4-oxadiazole-2-carboxylic acids and their esters decarboxylate. 

The presence of a series of alkylamines and amides (114—120, 125—129) in the gasterothorax characterizes the two ponerine ants, Mesoponera species (Table VIII), which contain 3-isopentyl-2,5-dimethylpyrazine (20h) as the major exocrine compound in their heads (Table III). The major amine is V-isoamyl-V-nonylamine (114). These compounds are perhaps utilized as defensive compounds against selected predators (41). 

However, two other areas are of interest (Fig. 9) namely, a) derivatisation of phenols or amines to phosphorus-containing compounds and b) on-column methylation. In the former, phosphorylation of 7 alcohols and 12 phenols with diethyl chlorophosphate in the presence of triethylamine at 60-70 C in benzene has been reported (35). Aliphatic alcohols, such as methanol, butanol or isoamyl alcohol react instantaneously while phenol and cresols require ca 1-1 1/2 hrs. and xylenols 3-4 hrs. for best results. 

The reductive alkylation of /V-alkylarylamines and diarylamine with ketones to give tertiary amines has been investigated by Greenfield and Malz, Jr.42 with platinum metal sulfides that had been shown to be excellent catalysts for the reductive alkylation of primary arylamines with ketones37 (see eq. 6.15). Good conversions to tertiary amines were obtained with relatively unhindered secondary arylamines and less hindered ketones. The relative ease in the reductive alkylation of diarylamines with ketones was in the following order cyclohexanone > acetone > ethyl methyl ketone > isoamyl methyl ketone > isobutyl methyl ketone. For example, 58% of diphenylamine was converted to iV-alkyldiphenylamine with cyclohexanone over rhodium sulfide at 150°C and 3.4-5.5 MPa H2 (eq. 6.19), while with isobutyl methyl ketone, a conversion of only 28% was obtained even at 235°C with in the same reaction time. 

The thiazolyl radicals are, in comparison to the phenyl radical, electrophilic as shown by isomer ratios obtained in reaction with different aromatic and heteroaromatic compounds. Sources of thiazolyl radicals are few the corresponding peroxide and 2-thiazolylhydrazine (202, 209, 210) (see Table III-34) are convenient reagents, and it is the reaction of an alkyl nitrite (isoamyl) on the corresponding (2-, 4-, or 5-) amine that is most commonly used to produce thiazolyl radicals (203-206). The yields of substituted thiazole are around 40%. These results are summarized in Tables III-35 and ni-36. 

Eleven and five-tenths grams (0.50 gram atom) of sodium is added in small portions to a stirred solution of 0.15 g. of powdered ferric nitrate in 300 ml. of liquid ammonia. (Hood.) The reaction mixture is cooled in a solid carbon dioxide-ethanol bath during this and subsequent operations. After the blue color of liquid ammonia solution is discharged (15-20 minutes after addition of the sodium), the temperature of the reaction mixture is adjusted to —50° and 53 g. (0.50 mole) of isoamyl chloride is added at the rate of 30-4 0 drops per minute. Stirring is continued for 1 hour after completion of the addition. The excess ammonia is then allowed to evaporate slowly, and the residue is hydrolyzed by the dropwise addition of excess water. Twenty grams of sodium hydroxide is then added, and the mixture is extracted with ether. Distillation of the ether followed by fractionation of the residual liquid gives a 40% yield of 3-methyl-l-aminobutane with a 10% recovery of alkyl chloride. The amine boils at 95°. 

The isodiazotate salts (19) of 2-amino-3-methyl- and 3-amino-2,5-dimethyl-pyrazines (17, R =R = H R = Me R = R = Me, R = H, respectively) [prepared from the corresponding amine by refluxing with sodium amide in diethyl ether and allowing the resulting sodium salt (18) to react with isoamyl nitrite] on treatment with hydriodic acid gave 2-amino-5-iodo-3-methyl- and 2-amino-5-iodo-... 

When radioactive pyridoxine hydrochloride was orally supplemented to evaluate vitamin Be metabolism in adult domestic cats, two unknown radioactive compounds (compounds X and Y) were excreted in the urine.The Rf values of compound X (7 f values 0.95, 0.83, 0.2, 0.5, and 0.62) and compound Y (Rf values 0.35, 0.20, 0.22, 0.32, and 0.25) were identical to those of pyridoxine-3-sulfate and Wmethylpyridoxine, respectively, but not to those of pyridoxine (Rf values 0.73, 0.83, 0.78, 0.52, and 0.62) in various solvent systems [0.5% ammonium hydroxide, 95% ethanol, chloroform-methanol (3 1 vol/vol), isoamyl alcohol-acetone-triethyl-amine-water (24 18 8 6 vol/vol), and 2-butanol-1.5N ammonium hydroxide (3 1 vol/vol), respectively] by TLC on silica gel plates. 

In an acidic medium (pH-1.7) and at a temperature not higher than 10°C, chromium(VI) reacts with H2O2 ( 0.02 M) to form blue perchromic acid which can be extracted into ethyl acetate, isoamyl alcohol, or similar oxygen-containing solvents. These methods permit the separation of Cr from V, Fe, and most other metals [7j. Perchromic acid can also be extracted with solutions of tertiary amines or quaternary ammonium salts [8,9]. 

Different characterization techniques were used to evaluate the immobilization and acidic properties of Keggin structured tungstophosphoric and molybdophosphoric acids impregnated on an amine-functionalized SiMCM-41 support. The characteristics of prepared catalysts were correlated to the activity in the esterification of acetic acid with isoamyl alcohol to obtain isoamyl acetate. 

The MPA and TPA based catalysts supported on a new amine-functionalized SiMCM-41 carrier showed important activity in the esterification reaction of acetic acid with isoamyl alcohol. On the other hand, low TPA (MPA) solubility during the leaching was observed. Then, these catalysts are very attractive for their use in liquid medium reactions. 

ISOAMYL METHANOATE (110-45-2) C4H12O2 CsH C(0)OCH Forms explosive mixture with air [explosion limits in air (vol %) 1.2 to 8.0 flash point 77°F/25°C Fire Rating 2]. Violent reaction with strong oxidizers. Incompatible with sulfuric acid, nitric acid, caustics, aliphatic amines, isocyanates. Flow or agitation of substance may generate electrostatic charges due to low... 

ISOAMYL ALCOHOL (123-51-3) Forms explosive mixture with air (flash point 109°F/43°C). Violent reaction with strong oxidizers, reducing agents, hydrogen trisulfide. Incompatible with acid anhydrides, acid chlorides, aliphatic amines, caustics, isocyanates, nitric acid, sulfuric acid. Attacks some plastics, rubber, and coatings. 

The only fact not clearly compatible with this mechanism is the observation (192,193) that benzoyl peroxide promotes the formation of telomers between phosphite and methacrylic acid. Other catalysts such as sodium methoxide, triethyl amine, and isoamyl iodide are less effective. 

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