Di-n-butyl amine

This reaction represents a general method for the preparation of secondary amines thus, di-n-butyl amine has been obtained from di-w-butyl cyanamide in yields of 75 per cent of the theoretical amount. 

SYNS n-BUTYL-l-BUTANAMINE Dl-n-BUTYLAMINE DI(n-BUTYL)AMINE (DOT)... 

Examples include the synthesis of diallylamine (88%) and di-n-butyl-amine (75%). ... 

Isocyanate Content Isocyanate levels in polyurethane preparations were measured on 2g samples taken from the polym-erizate and immediately cut into small pieces which were then promptly immersed in excess 0.05 N di(n-butyl)amine solution in dry tetrahyrofuran which was contained in an iodine flask. The gross weight of reagent plus flask was very accurately determined ahead of time to enable the exact weight of the added polyurethane sample to be subsequently determined by difference. Excess di(n-butyl)amine was titrated with 0.05N hydrochloric acid to the bromcresol green endpoint to enable calculation of the sample isocyanate concentration. 

The various aspects of oxidative polymerization of phenols have been thoroughly reviewed. Most commonly PPEs are produced by the self-con-densation of a monovalent phenol in the presence of oxygen and a metal-amine-complex catalyst. Manganese, copper and cobalt can be used as the metal in the catalyst. Cu+ is most commonly utilized. For example, the preparation of the catalyst can be achieved by stirring cuprous bromide and di-n-butyl amine in toluene. ... 

Lengthening of the alkyl chain makes only relatively slight differences to the piiTa values of primary amines (Table 2). After a very small increase in ethylamine they remain almost constant up to n-decyl-amine, after which there seems to be a slight decrease. Chain branching also produces very little effect. Amongst secondary amines (Table 3) there is evidence of the values rising to a maximum at di-n-butyl-amine, after which they assume an almost constant value. 

Into a 750 ml. round-bottomed flask furnished with a reflux condenser place a solution of 34 g. (18-5 ml.) of concentrated sulphuric acid in 100 ml, of water add 33 g. of di-n-butyl cyanamide and a few fragments of porous porcelain. Reflux gently for 6 hours. Cool the resulting homogeneous solution and pour in a cold solution of 52 g. of sodium hydroxide in 95 ml. of water down the side of the flask so that most of it settles at the bottom without mixing with the solution in the flask. Connect the flask with a condenser for downward distillation and shake it to mix the two layers the free amine separates. Heat the flask when the amine with some water distils continue the distillation until no amine separates from a test portion of the distillate. Estimate the weight of water in the distillate anp add about half this amount of potassium hydroxide in the form of sticks, so that it dissolves slowly. 

Peggion E, Cosani A, Mattucci AM, Scoffone E (1964) Polymerization of gamma-ethyl-L-glutamate-N-carboxyanhydride initiated by Di-N-butyl and Di-isopropyl amine. Biopolymers 2 69-78... 

Figure 1. Formation of carbonyl groups in 0.1 mm PP films as a function of irradiation time in Xenotest 150 (13). (UVA)2-(2 -hydroxy-3, 5 -di-tert-butylphenyl)-5-chloro-benzotriazole (Ni-Comp) Nickelf2,2 -thiobis-(4-tert-octylphenolate)]-n-butyl-amine (Benzoate) 2,4-di-tert-butylphenyl-3,5-di-tert-buty 1-4-hydroxy-benzoate (HALS) Bis-(2,2,6,6-tetramethyl-piperidinyl-4)sebacate.

The bis-diethylacetal of di-(4-oxo-n-butyl)amine (182) was obtained from y-aminobutyraldehyde diethylacetal (180) and y-chlorobutyral-dehyde acetal (181) and, after removal of acetal protecting groups, converted into 1-formylpyrrolizidine (183) without isolation of the intermediates. The final condensation was achieved by Babor et oZ.,109 who isolated 1-formylpyrrolizidine in ca. 10-15% yield at pH 4—4.5. Hydrogenation of the compound over platinum afforded 1-hydroxymethylpyrrolizidine, which they claimed to be ( + )-isoretronecanol. Leonard and Blum123 carried out the same condensation at pH 7 and reduced the resultant aldehyde, without isolation, with sodium boro-... 

The reaction of III with two or four equivalents of n-butyllithium resulted in the formation of a new product, N, N-di-n-butyl-terf-butylamine (VI), in yields up to 16% of theory. This previously unknown tertiary amine was identified by infrared and mass spectrometric analyses. A comparison of the mass spectrum of VI with that of the known tri-n-butylamine (Table I) shows thait the same major peaks appear but in quite... 

SYNS BU2AE DIBUTYLAMINOETHANOL 2-DIBUTYLAMINOETHANOL 2-DI-n-BUTYL-AMINOETHAN OL N,N-DI-n-BUTYLAMINOETHANOL pOT) P-N-DIBUTYLAMINOETHYL ALCOHOL N,N-DIBUTYLETHANOLAIvnNE N,N-DIBUTYL-N-(2-HYDROXYETHYL)AMINE... 

Deoxygeuation of N-oxides. Amine oxides are deoxygenated to the corresponding amines by reaction with iron pentacarbonyl in boiling di-n-butyl ether. ... 

The slight effect of solvent upon the rate of decomposition is characteristic of tertiary dialkyl peroxides. For example, the rate of decomposition of di-r-butyl peroxide is altered only slightly by changing from the gas phase through hydrocarbon solvents to tri-n-butyl amine (Table 66). These results indicate that there is little ionic character in the activated complex of the rate-determining step (2). 

The variation in solvents that are available for synthesis with the aid of organomagnesium compounds is rather limited most of the research in this field is done in ethereal solvents, such as diethyl ether, di-n-butyl ether, tetrahydrofuran, furan, anisole, and 1,2-dimethoxyethane. Some amines, such as triethylamine, dimethylaniline, and a few others of that type, have also been applied. 

Masamune has documented the addition of optically active ester enolates that afford lanfi-aldol adducts in superb yields and impressive stereoselectivity (Eq. (8.3)) [4]. The generation of a boryl enolate from 8 follows from groundbreaking studies of ester enolization by Masamune employing dialkyl boryl tri-flates and amines [5]. Careful selection of di-n-alkyl boron triflate (di-n-butyl versus dicyclopentyl or dicyclohexyl) and base (triethyl amine versus Hiinigs base) leads to the formation of enolates that participate in the <2u//-selective propionate aldol additions. Under optimal conditions, 8 is treated with 1-2 equiv of di-c-hex-yl boron triflate and triethyl amine at -78 °C followed by addition of aldehyde the products 9 and 10 are isolated in up to 99 1 antv.syn diastereomeric ratio. The asymmetric aldol process can be successfully carried out with a broad range of substrates including aliphatic, aromatic, unsaturated, and functionalized aldehydes. 

Neutralization with caustic soda forms the sodium salt and liberates 2 moles of amine for recycle. Sodium di (n-butyl) sulfamate, a textile mercerizing assistant, is prepared likewise from di (n-butyH amine. 

CH3-CH2-CH2-CH2-NH2 + OC>N-CH2-CH2-CH2-CH3 CH3-CH2-CHz-CH2-NH-C-NH-CH2-CH2-CH2-CH3 1-butyl amine butyl isocyanate di-N-butyl urea... 

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