Hyperthermia, induced

Flanders, K.C., Winokur, T.S., Holder, M.G., Spom, M.B. (1993). Hyperthermia induces expression of transforming growth factor beta in rat cardiac cells in vitro and in vivo. J. Clin. Invest. 92, 404-410. 

Fenugreek leaves possess anti-inflammatory and antipyretic effect. The leaf extract reduces formalin-induced oedema in single dose (fenugreek 1000 and 2000 mg/ kg, sodium salicylate 300mg/kg). It also reduces hyperthermia induced by Brewer s yeast 1-2 h after administration (Ahmadiani et al., 2001). 

B. Kjeldstad, A. Johnson, K. M. Furuheim, A. Schie Bergan and J. Krane (1988). Hyperthermia induced polyphosphate changes in Propionibacterium acnes as studied by 31P-NMR. Z. 

Miyamoto K, Sasaki M, Okudo T, et al. Four cases suspected of malignant hyperthermia induced by halothane and succinylchohne. Hiroshima J Anesth 1983 18 157. 

Britt BA, Webb GE, LeDuc C. Malignant hyperthermia induced by curare. Can Anaesth Soc J 1974 21(4) 371-5. 

Hyperthermia induced by an elevation in ambient temperature following RF radiation is known to be associated with fetal developmental effects. 2-Methoxyethanol is a known teratogen. In a study on laboratory animals it was demonstrated that combined exposure to RF and 2-methoxyethanol enhanced the adverse effects produced by either agent alone. It was also noted that teratogenic effects of 2-methoxyethanol were observed at levels below those found for the solvent alone, when it was co-administered with RFJ251... 

T. Shinohara, N. Takahashi, T. Ooie, M. Ishinose, M. Hara, H. Yoncmoshi, T. Saikawa and H. Yoshimat-su, Estrogen inhibits hyperthermia -induced expression of heat shock protein 72 and cardioprotection against ischemia/reperfusion injury in female rat heart, J. Mol. Cell. Cardiol. 37, 1053-1061 (2004). 

Cardiac dysrhythmias Dehydration Electrolyte disturbances Hyperthermia-induced Self-inflicted injury... 

Convection of heat via blood depends primarily on the local blood flow in the tissue and the vascular morphology of the tissue. Thermal diffusion is determined by thermal conductivity in the steady state, and thermal diffusivity in the unsteady state. In addition to these transport parameters, we need to know the volumes and geometry of normal tissues and tumor. In general, tumor volume changes as a function of time more rapidly than normal tissue volume. In special applications, such as hyperthermia induced by electromagnetic waves or radiofrequency currents, we need electromagnetic properties of tissues—the electrical conductivity and the relative dielectric constant. In the case of ultrasonic heating, we need to specify the acoustic properties of the tissue—velocity of sound and attenuation (or absorption) coefficient. 

During hyperthermia, terms representing the heat input to a specific tissue or whole body must be added to the proper system equation(s). For example, during whole-body or local hyperthermia induced by radiofrequency currents, microwaves, or ultrasound, a heat-generation term is added to the section of the body being heated. During hyperthermia with blood perfusion, the afferent blood temperature is set at a desired value, and the efferent blood is circulated to the central blood pool, or to the extracorporeal device used for heating the blood. Suitable numerical... 

Johnson Rowsey, P., Yang, Y. L., and Gordon. C. J. (2002). Peripheral cholinergic pathway modulates hyperthermia induced by stress in rats exposed to open-field. stress. J. Appl. Phy.siol. 92, 789-794. 

Ning S, Macleod K, Abra RM, Huang AH, Hahn GM. Hyperthermia induces doxorubicin release from long-circulating liposomes and enhances their anti-tumor efficacy. Int J Radiat Oncol Biol Phys 1994 29 827-834. 

Wang, Y. et al. Rrotective effect of Fructus Lycii polysaccharides against time and hyperthermia-induced damage in cultured seminiferous epithelium. J Ethnopharmacol, 82, 169, 2002. 

Mirkes PE (1987) Hyperthermia-induced heat shock response and thermotolerance in postimplantation rat embryos. Dev Biol 119 115-122 Mirkes PE, Cornel L (1992) A comparison of sodium arsenite- and hyperthermia-induced stress responses and abnormal development in cultured postimplantation rat embryos. Teratology 46 251-259... 

Hyperthermia. - The ability to tolerate heat stress decreases with age. EPR studies on frozen liver samples from rats have revealed changes in the intensity of signals from endogenous metals and a semiquinone species. Related studies have shown that hyperthermia induces the appearance of signals from ceruloplasmin, haem-coordinated NO and a semiquinone species in the blood. These changes were attributed to increased NOS and XO activities and were proposed to underlie the observed systemic responses e.g. hypotension). Other workers have examined the mechanisms by which radicals enhance the induction of apoptosis in human lymphoma cells exposed to hyperthermia. ... 

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