Human lung adenocarcinoma

Yeh, S.L. and Hu, M.L., Oxidized [beta]-carotene inhibits gap junction intercellular communication in the human lung adenocarcinoma cell line A549, Food Chem. Toxicol., 41, 1677, 2003. 

Ogretmen, B., J. M. Kraveka, D. Schady, J. Usta, Y. A. Hannun, and L. M. Obeid. 2001. Molecular mechanisms of ceramide-mediated telomerase inhibition in the A549 human lung adenocarcinoma cell line. J Biol Chem 276(35) 32506-14. 

Miquel, K., Pradines, A., Terce, F., Sehni, S., and Favre, G., 1998, Compehhve inhibition of choline phosphotransferase by geranylgeraniol and famesol inhibits phosphatidylchohne synthesis and induces apoptosis in human lung adenocarcinoma A549 ceUs. JBiol Chem. 273 26179-26186... 

A549 cells (Human lung adenocarcinoma epithelial cell line). Subculture once a week, maintain in 5% CO, at 37°C. 

Weitzel DH, Vandre DD. Differential spindle assembly checkpoint response in human lung adenocarcinoma cells. Cell Tissue Res 2000 300 57-65. 

Tateishi, M., Ishida, T., Mitsudomi, T., Kaneko, S., and Sugimachi, K. 1991. Prognostic value of c-erbB-2 protein expression in human lung adenocarcinoma and squamosa cell carcinoma. Eur. J. Cancer27 1372-1375. 

Tetrapeptide quinones derived from (3-lapachone, (II), and doxorubicin, (III), prepared by Blokhin (4) were effective against human lung adenocarcinoma cell line, A549, and human prostatic cancer cell line, DUPRO. 

In vitro methods to measure ciliary beat frequency can be performed on explants of ciliated mucosa [64] or on different types of ciliated cells, such as ciliated chicken embryo trachea cells [123], nasal cell lines derived from carcinomas of epithelial origin (RPMI2650, BT, NAS 2BL), or human lung adenocarcinoma cell line Calu-3... 

Cell line expressing oncogenic KRAS, Cell lines A549, human lung adenocarcinoma CaLu-1, human nonsmaU cell lung cancer MDA-MB-231, human breast cancer PANC-1, human pancreatic cancer MMTV, mouse mammary tumor virus n/d, not determined p-, phosphorylated form of a protein. 

Vainio H, Husgafvel-Pursiainen K, Antilla S, et al. 1993. Interaction between smoking and asbestos in human lung adenocarcinoma. Environ Health Perspect Suppl 101 (3) 189-192. 

C, Birbes H, Hannun YA, Obeid LM. Role of ceramide in mediating the inhibition of telomerase activity in A549 human lung adenocarcinoma cells. J. Biol. Chem. 2001 276 24901-24910. 128. 

Yano, S., Nokihara, H., Hanibuchi, M., Parajuli, R, Shinohara, T., Kawano, T. and Sone, S. (1997). Model of malignant pleural effusion of human lung adenocarcinoma in SCID mice. Oncol. Res. 9, 573-579. 

For human lung adenocarcinoma A549 cells, RPMI-I640 medium (Invitrogen) supplemented with 10% FBS and kanamycin sulfate (lOOpg/mL). 

Yang, S.-C. et al., Identification of benzo[a]pyrene 7,8-diol 9,10-epoxide N2-deoxyguanosine in human lung adenocarcinoma cells exposed to cooking oil fumes from frying fish under domestic conditions, Chem. Res. Toxicol., 13, 1046, 2000. 

Reilly MAO, Gazdar AF, Morxi RE, Whitsett JA (1988) Differential effects of glucocorticoid on expression of surfactant proteins in a human lung adenocarcinoma cell line. Biochim Biophys Acta 970 194-204... 

Shi J, Zheng D, Liu Y, Sham MH, Tam P, Farzaneh F, Xu R. Overexpression of soluble TRAIL induces apoptosis in human lung adenocarcinoma and inhibits growth of tumor xenografts in nude mice. Cancer Res 2005 65 1687-1692. 

Activation of polycyclic aromatic hydrocarbon trans-diliydrodiol proximate carcinogens by human aldo-keto reductase (AKR1C) enzymes and their functional overexpression in human lung adenocarcinoma (A549) cells. J. Biol. Chem., 277, 24799-24808. 

Mitra, P., Maceyka, M., Payne, S.G., Lamour, N., Milstien, S., Chalfant, C.E., and Spiegel, S. Ceramide kinase regulates growth and survival of A549 human lung adenocarcinoma cells. FEES Lett, 581, 2007, 735-740. 

Cytotoxicity is denoted by inhibition of human epidermal carcinoma (KB-16), human lung adenocarcinoma (A549), human colon carcinoma (HT-29), and murine lymphocytic leukemia (P-388) cells at half maximal inhibitory concentration (IC50) values of pg/mL. bFor the cell lines tested, an IC50 value of <4 pg/mL is regarded as active. 

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