Homeopathic preparations

Complementary and alternative medicine therapies, such as acupuncture, biofeedback, chiropractic manipulation, dietary supplements, herbal therapy, and homeopathic preparations, are used by individuals with allergic rhinitis.29,30 Use of bromelain, gingko, ginseng, licorice, quercetin, and Urtica dioica has been reported, but large-scale studies documenting efficacy are lacking.31,32 Caregivers should inquire routinely about patients use of alternative therapies and counsel patients about the lack of validated data to support such practices.12... 

Many preparations of feverfew are available to the general public from health food shops and similar outlets in the U.K. They take the form of herbal or homeopathic preparations. The herbal preparations may contain just dried leaf in tablet or capsule form or indeed the dried whole plant. There are many different dosages on the market ranging from 25 to 390 mg per tablet or capsule. When the platelet antisecretory activity that could be extracted from some of these preparations was compared with that extracted from known amounts of feverfew, the apparent feverfew content of most preparations was found to be lower that that stated on the preparation [70]. In the case of the homeopathic preparation, no antisecretory activity was detected. 

M Good Manufacturing Practices (GMP) requirements of factory premises, plants and equipments. M Requirements of factory premises etc. for manufacture of homeopathic preparations. 

Arnica is believed to have topical counterirritant properties. It is used for unbroken chilblains (swelling of the hands and feet from exposure to damp cold), alopecia neurotica, and specifically for sprains and bruises. It is mainly used in homeopathic preparations and, to a lesser extent, in herbal products. 

Several chemicals are found in this short, yellow-flowering, wild-growing plant they are considered to alter the balance of some neurotransmitters such as serotonin, dopamine, GABA and norepinephrine. St John s wort is an inducer of CYP3A4, CYP1A2, CYP2D6 and P-gp and is known to interact with several commonly used drugs, Topical or homeopathic preparations of St John s wort are not likely to interact with prescribed medicines,... 

In Western medicine, picrotoxanes have played but a marginal role therapeutically. Picrotoxin was described as analeptic. Porter recorded that picrotoxin was found to be an antidote against chloral hydrate and in consequence it was used also as an antidote against barbiturate intoxication (2). It was this activity that made biomedical researchers aware of its potential as research tool in neurochemistry. Due to its high toxicity, even its use as antidote is restricted, however. Picrotoxin is employed to treat vertigo and nausea in homeopathic preparations (25i). 

Among the treatment options, topical decongestants, topical and oral antihistamines, mast cell stabilizers, dual-action/multiaction drugs, and certain nonsteroidal antiinflammatory agents have proven useful for alleviating the signs and symptoms associated with ocular allergic reactions. Homeopathic preparations have also become of interest to the ophthalmic community, and their scientific... 

Kerr HD, Yarborough GW. Pancreatitis following ingestion of a homeopathic preparation. N Engl J Med 1986 314(25) 1642-3. 

Anaphylaxis has been reported after the administration of a homeopathic preparation of mandragora (18). 

There are 4 specialized commissions at the MOH Phcirmaceuticals (9 members) Biologicals (6 members) Herbal and Homeopathic Preparations (5 members) and Medical Devices (6 members). Each commission gives a scientific statement on the assessment of the cliniccil safety and efficacy of the products under registration. They also comment on the scientific reasons for performing clinical trials in Bulgaria. All commissions fall under the responsibility of the NDI. 

Proof of efficacy is not required for homeopathic preparations cis long as no claims are made regarding efficacy in specific indications. 

For proprietary medicinal products bcised on traditional medicinal plants known for their hcirmlessness used under the form tisane and/or under other galenic forms, as well as for homeopathic preparations figuring in a pharmacopoeia, the manufacturer should submit ... 

Issing W, Klein P, Weiser M. The homeopathic preparation Vertigoheel versus Ginkgo biloba in the treatment of vertigo in an elderly population a double-blinded, randomized, controlled clinical trial. J Altern Complement Med 2005 11(1) 155-160. 

It is important to note that, although homeopathic preparations may frequently... 

Hagemann U. (2001) Pharmaceutical Products Containing Kava-Kava (Piper methysticumj and Kavain, Including Homeopathic Preparations with a Pinal Concentration up to D6, German Federal Institute for Drugs and Medical Devices (BfArM), Berlin, November 8. 

When a pharmaceutical establishment makes both homeopathic and non-homeopathic preparations, the area used for homeopathic preparations must be located in segregated premises. 

Ferley JP, Zmirou D, D Adhemar D et al (1989) A controlled evaluation of a homeopathic preparation in the treatment of influenza-hke symptoms, Br J Clin Pharmacol 27 329-335 Fetrow CW, AvUa JR (2001) Professional s handbook of complementary and alternative medicines, 2nd edn, Springhouse Corporation, Springhouse, PA Fontana GA, Widdicombe JG (2007) What is cough and what should be measured Pulm Pharmacol Ther 20 307-312... 

Homeopathic preparations of arnica are commonly used and are distinct from herbal preparations of arnica that are the subject of this entry (Leivers 2005). 

Preethi, K.C., C.K. Nair, and R. Kuttan. 2008. Clastogenic potential of Ruta graveolens extract and a homeopathic preparation in mouse bone marrow cells. Asian Pac.. Cancer Prev. 9(4) 763-769. 

Homeopathic herbal preparations. Homeopathic products are classified as over-the-counter or prescription drugs and are regulated under the Homeopathic Pharmacopoeia of the United States. Safety concerns that arise for an herb in crude form may not apply to homeopathic preparations of the same herb, and this document does not address herbal products in homeopathic forms. Essential oils. Essential oils are concentrations of specific volatile compounds. While many essential oils have a well-documented history of safe use by appropriately skilled persons, they often present toxicological concerns that are absent or moderate in the crude plant materials from which the oil is derived. Except for a small number of essential oils that have a history of internal use, the classification of essential oils is beyond the scope of this document. 

Furthermore the Ph. Eur. contains some general monographs including, for example, vaccines for human use, radiopharmaceutical preparations and homeopathic preparations. 

The British Phamacopoeia (B.P.) comprises of six volumes. Volume I and II encompass monographs of medicinal and pharmaceutical substances. Volume HI contains monographs on formulated preparations. Volume IV is about herbal active substances, herbal preparations and herbal medicinal products, material for use in the manufacture of homeopathic preparations, blood-related products, immunological products, radiopharmaceutical preparations and surgical materials. Volume V contains infrared reference spectra, appendices and supplementary chapters. There is also a single volume of the B.P. (Veterinary) containing monographs on products used in veterinary medicines. 

Pharmacovigilance in complementary and alternative medicine Pharmacovigilance in complementary and alternative medicine has attracted much attention worldwide. The awareness of the need for surveillance of adverse reactions to natural health products has stimulated the implementation of a reporting system for suspected adverse reaction in Italy From April 2002 to March 2007, 233 spontaneous reports of suspected adverse reactions to natural health products were collected. A large proportion of the suspected adverse reactions were serious hospitalization was reported in 35% of cases 6% reported life-threatening clinical events, and there were two fatal events. Most of the reported cases involved herbal products (66%) 21 reports were associated with 27 homeopathic preparations, most of which contained a mixture of substances 14 reports attributed the suspected reactions to products containing propolis. 

Double-blind, placebo-controlled clinical trials of homeopathic preparations of A. montana have shown questionable or no benefits in the treatment of postoperative pain, postoperative bruising, postoperative hemato-mas, postoperative swelling, muscle... 

Mineral trace element vitamin amino acid essential fatty acid botanical-, animal-, or microorganism-derived substances homeopathic preparation traditional preparations... 

Vitamin and mineral as both foods and drugs, botanicals (approved and not approved), teas as prescription and as over-the-counter Vitamin and mineral, plants, herbs, nutritional food supplements, naturopaths and homeopathic preparations, aromatherapies No definition of dietary supplements, regulations for foods, drugs, and Kampo... 

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