Hazardous disrupter

The use of radioactive material is a true terror weapon because it generates fear far out of proportion to the actual hazard, disrupts society, and creates a great economic impact. Radiation is especially frightening because, though it is deadly, human senses cannot detect it. Radiation cannot be seen, smelled, or felt. 

Baum, M. R. 1987. Disruptive failure of pressure vessels preliminary design guide lines for fragment velocity and the extent of the hazard zone. In Advances in Impact, Blast Ballistics, arui Dynamic Analysis of Structures. ASME PVP. 124. New York ASME. 

Recently, attention has focused on the potential hazardous effects of certain chemicals on the endocrine system because of the abihty of these chemicals to mimic or block endogenous hormones, or otherwise interfere with the normal function of the endocrine system. Chemicals with this type of activity are most commonly referred to as endocrine disruptors. Some scientists believe that chemicals with the ability to disrupt the endocrine system are a potential threat to the health of humans, aquatic animals, and wildlife. Others believe that endocrine disrupting chemicals do not pose a significant health risk, particularly in light of the fact that hormone mimics exist in the natural environment. Examples of natural hormone mimics are the isoflavinoid phytoestrogens (Adlercreutz 1995 Livingston 1978 Mayr et al. 1992). 

Biosorption strategies consist of a group of applications involving the detoxification of hazardous substances such as heavy metals instead of transferring them from one medium to another by means of biosorbents, which may be either microbes or plants. Biosorption options are generally characterized as being less disruptive and may henceforth be carried out on-site, thereby eliminating the need to transport the toxic materials to treatment sites.12 Biosorption is a very cost-effective method... 

Children sometimes differ from adults in their susceptibility to hazardous chemicals, but whether there is a difference depends on the chemical (Guzelian et al. 1992 NRC 1993). Children may be more or less susceptible than adults to health effects and the relationship may change with developmental age (Guzelian et al. 1992 NRC 1993). Vulnerability often depends on developmental stage. There are critical periods of structural and functional development during both pre-natal and post-natal life and a particular structure or function will be most sensitive to disruption during its critical period(s). Damage... 

Different organic acids, primarily lactic acid, have been successfully used for decontamination of whole livestock carcasses, and the application of different organic acids used for decontamination has also been tested in the fruit and vegetable industry. Organic acids other than lactic acid that are known to have bactericidal effects are acetic, benzoic, citric, malic, propanoic, sorbic, succinic and tartaric acids (Betts and Everis 2005). The antimicrobial action is due to a reduction in the pH in the bacterial environment, disruption of membrane transport, anion accumulation or a reduction in the internal pH in the cell (Busta et al., 2001). Many fruits contain naturally occurring organic acids. Nevertheless, some strains, for example E. coli 0157, are adapted to an acidic environment. Its survival, in combination with its low infective dose, makes it a health hazard for humans. 

All of these chemicals pose an inhalation hazard but a toxic dose could also be obtained through skin absorption or ingestion. Factors that were considered when selecting potential candidate chemicals include global production, physical state of the material (i.e., gas, liquid, or solid), chemicals likely to cause major morbidity or mortality, potential to cause public panic and social disruption, chemicals that require special action for public health preparedness, history of previous use by the military, and/or involvement in a significant industrial accident. 

Some xenobiotics may have divergent mechanisms of autoimmune responses. For example, hydralazine demonstrates adduct reactivity as well as inhibition of DNA methylation [68,73], while procainamide inhibits DNA methylation, forms immunogenic NPA, and disrupts clonal selection in the thymus [68, 72, 74], It is this complicated pattern of effects that makes assessment of autoimmune potential in the laboratory for new xenobiotics almost impossible. Animal models can sometimes be recreated to resemble human disease [74], and thus may be useful for therapy considerations, but are difficult to utilize for screening chemicals for hazard potential due to the diverse nature of autoimmunity mechanisms and physiological presentation. While evidence supports many different mechanisms for xenobiotic-induced autoimmune reactions, none have conclusively demonstrated the critical events necessary to lead to the development of autoimmune disease. Therefore, it is difficult to predict or identify xenobiotics that might possess the potential to elicit autoimmune disorders. 

Risk The potential for damage to or loss of an asset. Risk, in the context of process security, is the potential for a catastrophic outcome to be realized. Examples of the catastrophic outcomes that are typically of interest include an intentional release of hazardous materials to the atmosphere, or the theft of hazardous materials that could later be used as weapons, or the contamination of hazardous materials that may later harm the public, or the economic costs of the damage or disruption of a process. 

It helps them to reduce systematically their use of hazardous chemicals and develop new products. Some companies have agreed on substances that need to be avoided. As documented In the case studies In Annex I of this report, they are Instructing their suppliers to phase out a range of carcinogenic, mutagenic and reproductive toxins, as well as some persistent, bloaccumulative, and endocrine disrupting chemicals. 

Immunological and Lymphoreticular Effects. No studies were loeated regarding immunological and/or lymphoreticular effects in humans or animals following exposure to 3,3 -diehlorobenzidine by any route of exposure. The immime system does not appear to be a sensitive target of 3,3 -dichlorobenzidine toxicity. Consequently, immune system disruptions are not expected in humans exposed to 3,3 -dichloro-benzidine at the levels at which it occurs at hazard waste sites. 

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