Handbook Beilstein reference

Handbook of Data on Organic Compounds. Eds R. C. Weast and M. J. Astle. Boca Raton, Florida CRC Press. Data include physical and spectral properties and references. Chemical Abstracts Service registry number and Beilstein reference. 

For rapid access to information such as mp, bp, density, solubility, optical rotation, A max, and crystal form, one turns first to the Handbook of Chemistry and Physics where information is found on some 15,000 organic compounds, including the Beilstein reference to each compound. These compounds are well known and completely characterized. The majority are commercially available. The Merck Index contains information on nearly 10,000 compounds, especially those of pharmaceutical interest. In addition to the usual physical properties, information and literature references to synthesis, isolation, and medicinal properties, such as toxicity data, are found. The last third of the book is devoted to such items as a long cross index of names (which is very useful for looking up drugs), a table of organic name reactions, an excellent section on first aid for poisons, a list of chemical poisons, and a listing of the locations of many poison control centers. 

Beilstein reference numbers are listed in such handbooks as CRC Handbook of Chemistry and Physics and Lange s Handbook of Chemistry. Additionally, Beilstein numbers are included in the Aldrich Handbook of Fine Chemicals, issued by the Aldrich Chemical Company. If the compound you are seeking is listed in one of these handbooks, you will find that using Beilstein is simplified. 

A literature search that ultimately requires you to read one or more papers in the scientific journals is best conducted if you can identify a particular paper central to the study. Often, you can obtain this reference from a textbook or a review article on the subject. If this is not available, a search through Beilstein is required. A search through one of the handbooks that provides Beilstein reference numbers (see Section 29.10) may be helpful. Searching through Chemical Abstracts would be considered the next logical step. From these sources, you should be able to identify citations from the original literature on the subject. 

Beilstein File. Beilstein first went on-line on STN International in December 1988 with information on 350,000 compounds, and several months later it was also on Dialog. Beilstein Online now comprises data on five million compounds. The organic substance records contain the critically reviewed and evaluated documents from the beilstein Handbook of Organic Chemist main volume and supplements 1—5, which cover the chemical Hterature from 1779 through 1979. These evaluated data are indicated as Handbook Data in the notes of Hterature references. The Beilstein Eile also contains organic substance records for unreviewed excerpts from the primary Hterature from 1980 to 1991. 

Beilstein Handbook of Organic Chemistry. This reference (55) is one of the most significant collections of data in organic chemistry. The physical and chemical properties of organic compounds are tabulated in more than 500 fields. Most of these fields are searchable, and a sample of the record for chlorobenzene [108-90-7] is shown in Table 3. 

At this moment, the NIST Chemistry WebBook and the Beilstein are the two most useful search tools for molecular structure and property relations. There are many more types of properties available in the research literature of interest only to a smaller set of readers these will not be listed in the general-purpose handbooks, but are to be found in specialized books and journals. Our ability to search for such properties in the research literature on the Internet is increasing rapidly, and students should practice doing such searches. Many of the required properties have not been tabulated in a searchable electronic database for example, flammability, toxicity, ozone hole potential, and greenhouse gas potential. Information on health, safety, and the environment that is publicly available on websites is listed in the references. 

Interestingly, the Beilstein Handbook (Ref. 10) used this type of labelling in the III-IV supplement, while, for supplement V, a change to sugar terms is evident. Originally, the trivial names isosorbide, isomannide, and isoidide were used in the main volume, as well as in Supplements I and II. It should, however, be pointed out that Beilstein names in supplement III-IV are based on an older stereochemical reference system according to which 3 is (3aR)-(3ar, 6ac)-hexahydrofuro-[3,2-h]furan-3c, 6f-diol. 

The Beilstein Handbook of Organic Chemistry (Beilstein s Handbook der Organi-schen Chemie) is a reference work containing information and data relating to the structure, preparation and properties of organic compounds reported in the primary literature. The information is condensed into short entries, each of... 

Since many of the fission products obtained have never been accurately described, the larger handbooks, such as Beilstein, are of little help. On the other hand, it is absolutely necessary to study the available patents carefully, and, if necessary, to perform quantitative,analysis on the products obtained, as pointed out in the introduction to this section. In this connection, reference should be made to the literature compilation given by Fierz and Matter (9, above). Note especially, Forster and Hanson, /. Soc. Dyers Colourists, 42, 272 (1926). 

The chief sources of data for particular compounds are Chemical Abstracts and the numerous reference handbooks, including Beilstein. Information on relatively simple compounds can often be obtained from handbooks such as the following ... 

Beilstein Handbook Reference) Acetaal Acetal Acetal diethylique Acetaldehyde diethyl acetal Acetaldehyde ethyl acetal Ace Acetol Aceton NS Acetron GP AI3-24135 AT-20GF BRN 1098310 Oiaethylacetal 1,1-Diaethoxy-aethan 1,1-Diathoxy-athan 1,1-Diethoxy-elhaan 1,1-Diethoxyethane Diethyl acetal Diethylacetal 1.1-Dletossietano EINECS 203-310-6 Ethane,... 

Beilstein Handbook Reference) Acetaldehyde, oxime Acetaldoxime AI3-52258 Aldoxime BRN 1209252 CCRIS 1379 EINECS 203-47SS Ethanal oxime Ethylidenehydroxylamine HSDB 2662 Hydroiminoethane NSC 4974 UN2332 USAF AM-5. Needles mp = 45° bp = 115° d = 0.9656 km = 190 nm (e = 5012) freely soluble in EtOH, Et20, soluble in H2O, CHCI3. 

Beilstein Handbook Reference) Acetanhydride Acetic acid, anhydride Acetic anhydride Acetic oxide Acetyl... 

Beilstein Handbook Reference) Acetoacetyl-o-aniside Acetoacetyl-o-anisidide AI3-04822 BRN 1459707 Butanamide, N-(2-methoxyphenyl)-3-oxo- EINECS 202-131-0 0-Methoxyacetoacetanilide NSC 7563. 

Beilstein Handbook Reference) Aceto-acet-o-toluidide Acetoxeto-ortho-toluidide Acetoacetyl-2-methylanilide 2-Acetoxetylaminotol-uene AI3-08708 BRN 2099098 Butanamide, N-(2-methylphenyl)-3-oxo- CCRIS 7750 EINECS 202-267-0 2-Methyiaceto-acetanilide N-(2-Methylphenyl)-3-oxobutanamide NSC 7655. 

Beilstein Handbook Reference) Acetylene dichlotide BRN 1719345 CCRIS 6227 1,2-DCE 1,2-Dichlor-aethen 1,2-Dichlor-athen 1,2-Dichloroethene 1,2-Dichloroethylene sym-Dichloro-ethylene Diohloro-1,2-ethylene Dioform EINECS... 

Beilstein Handbook Reference) 5-Aza-IO-arsenaanthrxene chloride Adamsit Adamsite BRN 0178698 Caswell No. 648 10-Chloro-5,10-dihydro-arsacridine 10-Chloro-5,10-dihydrophenars-azine Chlorodiphenylaminearsine ... 

Beilstein Handbook Reference) Adipic acid dinitrile Adipinsaeuredinitril Adipodinitrile Adiponitrile Adipyidinitrile AI3-11080 BRN 1740005 CCRIS 4570 1,4-Dicyanobutane EINECS... 

Beilstein Handbook Reference) Aceto DIPP Agerite White AgeRite W AI3-14324 Antigene F Antioxidant 123 Antioxidant DNP ASM-DNT 1,4-Benzenediamine, N,N -di-2-naphthalenyl- N,N -Bis-(2-naftyl)-p-fenylendiamin 1,4-Bis(2-naphthylamino)-benzene N,N -Bis((3-naphthyl)-p-phenylenediamine N,N -Bis(2-naphthyl)-p-phenylenediamine BRN 2224419 CCRIS 6026 Oi-(3-naphthyl-p-phenyldi-amine Di-(J-naphthyl-p-phenylenediamine s-Di(P-naphthyl)-p-phenylenediamine N,N -Di-p-naphlhyl-p-phenylene-diamine N,N -Di-2-naphthalenyl-1,4-benz-enediamine N,N -Di-2-naphthyl-p-phenylenediamine Diafen NN DNPD Dnpda Dwu-p-naftylo-p-fenylodwuamina EINECS 202-249-2 Nonox CL NSC 3410 p-Phenylenediamine, N,N -(di-2-naphthyl)- N,N -p-Phenylenebis(2-naphthylamine) Santowhite CL Tisperse MB-2X. Antioxidant, An antidegradant for latex, nitrile rubber, styrene-butadiene and nitrile-butadiene rubber. Solid mp = 224-230° d n 1.22-1.28 insoluble in H2O, EtOH, soluble in organic solvents LDso (rat orl) = 4500 mg/kg. Vanderbilt R. T. Co. Inc. 

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