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Hand eczema

Although most nickel sensitization results from nonoccupational exposures, nickel dermatitis was historically a problem in workplaces where there was a high risk of continuous contact with soluble nickel, eg, in electroplating (qv) shops. Improved personal and industrial hygiene has largely eliminated this problem. However, there are a few occupations involving wet nickel work, particularly where detergents faciUtate the penetration of skin by nickel, where hand eczema may occur (126). [Pg.13]

Nielsen et al. (1990) fed 12 women with hand eczema and known allergy to nickel a diet (oatmeal, soy beans, cocoa) with five times the normal level of nickel (about 0.007 mg/kg/day) for 4 days. An aggravation of hand eczema was found in 6/12 by day 4 after the start of the challenge, and although excess nickel was excreted by 2 days after the last treatment, further exacerbation of hand eczema was... [Pg.86]

Santucci et al. (1994) gave increasing daily doses of nickel (0.01-0.03 mg/kg/day) as nickel sulfate to eight nickel-sensitive women for up to 178 days. A significant clinical improvement in hand eczema was observed in all subjects after 1 month of treatment, and continued treatment resulted in healing of all dermal lesions except for those on the hands. Measurement of urine and serum nickel suggested a decrease in the absorption of nickel and an increase in the excretion of nickel with longer exposure. [Pg.87]

Christensen OB, Moller H. 1975. External and internal exposure to the antigen in the hand eczema of nickel allergy. Contact Dermatitis 1 136-141. [Pg.227]

Cronin E, DiMichiel AD, Brown SS. 1980. Oral challenge in nickel-sensitive women with hand eczema. In Brown SS, Sunderman FW Jr, eds. Nickel Toxicology. New York, NY Academic Press, 149-152. [Pg.228]

Jordan WP, King SE. 1979. Nickel feeding in nickel-sensitive patients with hand eczema. J Am Acad Dermatol 1 506-508. [Pg.238]

Nielsen GD, Jepson LV, Jorgensen PJ, et al. 1990. Nickel-sensitive patients with vesicular hand eczema Oral challenge with a diet naturally high in nickel. Br J Dermatol 122 299-308. [Pg.245]

Wilkinson DS, Wilkinson JD. 1989. Nickel allergy and hand eczema. In Maibach HI, Menne T, eds. Nickel and the skin Immunology and toxicology. Boca Raton, FL CRC Press, Inc., 133-163... [Pg.257]

A 27-year-old woman, a pharmacist, had dermatitis on three separate occasions a few hours after she started to take oral deflazacort 6 mg for vesicular hand eczema (185). On each occasion, her symptoms included a widespread macular rash mainly on the inner aspects of her arms and legs and buttocks. She also had severe scaling, fever, nausea, vomiting, malaise, and hypotension. A skin biopsy was consistent with erythema multiforme, and direct immunofluorescence showed granular deposits at the dermoepidermal junction. Patch tests to the commercial formulation of deflazacort 6 mg (1% aqueous solution) and to pure deflazacort (1% aqueous solution) were positive, but there were no cross-reactions to other glucocorticoids. [Pg.24]

Agner, T. Non-invasive measuring methods for the investigation of irritant patch test reactions a study of patients with hand eczema, atopic dermatitis and controls. Acta Derm. Venereol. 173 (Suppl.), 1-26 (1992). [Pg.131]

A 33-year-old woman with atopic hand eczema and allergic rhinitis was given Noviform, an eye ointment containing bibrocathol (bismuth oxide and tetrabromo-cathechol), for periorbital dermatitis and noticed an exacerbation of her dermatitis (32). A patch test was positive for bismuth oxide. [Pg.521]

A 54-year-old man treated with photochemotherapy for disabling hand eczema developed flu-like symptoms, which lasted for 48 hours and occurred repeatedly within 2 hours after oral methoxsalen 50 mg. In addition to a fever up to 39 C, he had headache, nausea and vomiting, fatigue, dyspepsia, and muscle aches. [Pg.2824]

Contact with propylene oxide may cause severe skin and eye irritation. Cases of allergic contact dermatitis and hand eczema have been described. Inhalation of propylene oxide may result in spasm, inflammation, and edema of the larynx and bronchi, as well as pulmonary edema leading to pneumonia. Symptoms of exposure may include burning sensation, coughing, wheezing, headache, nausea, and vomiting. Propylene oxide may cause central nervous system depression and other neurological disorders. [Pg.2132]

One case of allergic contact dermatitis from 1,1,1 -trichloroethane was located in the literature (Ingber 1991). A worker whose job included using 1,1,1-trichloroethane to clean metal plates developed severe acute hand eczema soon after starting the job. The eczema persisted throughout 3 years of employment. Patch tests at that time showed a positive reaction to 1,1,1 -trichloroethane. The eczema disappeared after a few weeks when contact with 1,1,1-trichloroethane was avoided. The possibility the allergic reaction to being caused by 1,1,1-trichloroethane stabilizer was not discussed. [Pg.78]

Cronin E. 1991. Formaldehyde is a significant allergen in women with hand eczema. Contact Dermatitis 25 276-282. [Pg.379]

Meding B, Swanbeck G. 1990. Occupational hand eczema in an industrial city. Contact Dermatitis 22 13-23. [Pg.412]

Rystedt I Work-related hand eczema and atopies. Contact Dermatitis 1985 12 164. (Ill) Yunginger JW Natural rubber latex allergy in Middleton E Jr, Reed CE, Ellis EF, Adkinson NF Jr, Yunginger JW, Busse WW (eds) Allergy. Principles Practice. St. Louis, Mosby, 1998. (evidence not coded)... [Pg.162]

General principles of prevention of occupational asthma, rhinoconjimctivitis and dermatitis (e.g. hand eczema or contact dermatitis) should be published by national regulatory and advisory bodies. [Pg.198]

Nielsen GD (1992) Oral challenge of nickel-allergic patients with hand eczema. In Nieboer E and Nriagu JO, eds. Nickel and Human Health ... [Pg.861]

Agrup G (1969) Hand eczema and other hand dematoses in south Sweden. Acta Derm Ve-nereol (Stockh) [Suppl] 49 61... [Pg.365]

Bjomberg A (1968) Skin reactions to primary irritants in patients with hand eczema. Oscar Isacsons Tryckeri AB, Goteborg... [Pg.366]

Nickel contact hypersensitivity has been documented extensively in both the general population and in a number of occupations in which workers were exposed to soluble nickel compounds. In several countries, it has been reported that 10-20% of the female population and about 1% of the male population show dermal sensitivity to nickel. Of these, 40-50% have vesicular hand eczema, which in some cases can be very severe and lead to loss of working ability. Oral nickel intake may aggravate vesicular hand eczema. Prostheses, or other surgical implants, made from nickel-containing alloys have been reported to cause nickel sensitization or to aggravate existing dermatitis. [Pg.511]

In 84 male woodwork teachers there was a high incidence of allergic reactions to colophony using patch tests to a supplemented European standard series and acetone extracts of wood dust of pine, spruce, juniper, and birch 19% had mild hand eczema and there was contact allergy to several allergens in the working environment, including benzisothiazolin-3-one, nickel, formaldehyde, and colophony [52 ]. [Pg.775]

Table 3. Sick-leave, medical consultation due to work-related hand eczema in different occupational groups (modified according to Smit et al. 1993)... Table 3. Sick-leave, medical consultation due to work-related hand eczema in different occupational groups (modified according to Smit et al. 1993)...
Table 5. Reported 1-year prevalence of hand eczema in men and women in occupations according to a population-based study in Gothenburg (Sweden) (modified according Meding and Swan-beck 1990)... Table 5. Reported 1-year prevalence of hand eczema in men and women in occupations according to a population-based study in Gothenburg (Sweden) (modified according Meding and Swan-beck 1990)...
Table 4. Prevalence of hand eczema in population-based studies (selection)... Table 4. Prevalence of hand eczema in population-based studies (selection)...
Country Method of case ascertainment No. of responders Measures of prevalence Prevalence of hand eczema (%) ... [Pg.7]

Burrows D, Corbett JR (1977) Industrial dermatitis in Northern Ireland. Contact Dermatitis 3 145-150 Christensen OB (1982) Prognosis in nickel allergy and hand eczema. Contact Dermatitis 8 7-15 Coenraads PJ, Diepgen TL (1998) Risk of hand eczema in employees with past or present atopic dermatitis. Int Arch Occup Environ Health 71 7-13... [Pg.15]

Kligman AM (1966) The identification of contact allergens in human assay. J Invest Dermatol 47 375-392 Kristensen 0 (1992) A prospective study of the development of hand eczema in an automobile manufacturing industry. Contact Dermatitis 26 341-345... [Pg.16]

Majoie IML, von Blomberg BME, Bruynzeel DP (1996) Development of hand eczema in junior hairdressers an 8-year followup study. Contact Dermatitis 34 243-247 Mathias CGT (1985) The cost of occupational skin disease. Arch Dermatol 121 332-334... [Pg.16]

Rystedt I (1985a) Hand eczema and long-term prognosis in atopic dermatitis (thesis). Acta Derm Venereol 117 1-59... [Pg.16]

Rystedt I (1985b) Work-related hand eczema in atopies. Contact Dermatitis 12 167-171... [Pg.16]


See other pages where Hand eczema is mentioned: [Pg.509]    [Pg.511]    [Pg.18]    [Pg.86]    [Pg.509]    [Pg.511]    [Pg.547]    [Pg.1349]    [Pg.561]    [Pg.563]    [Pg.313]    [Pg.3]    [Pg.15]    [Pg.16]   
See also in sourсe #XX -- [ Pg.3 , Pg.356 , Pg.499 , Pg.514 ]




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