Epsilon receptors

Wiegand TW, Williams PB, Dreskin SC, Jouvin MH, Kinet JP, Tasset DM, High-affinity oligonucleotide ligands to human IgE inhibit binding to Fc epsilon receptor, J. Immunol., 157 221-230, 1996. 

Shook JE, Kazmierski W, Wire WS, Lemcke PK, Hruby VJ, Burks TF (1988) Opioid receptor selectivity of beta-endorphin in vitro and in vivo mu, delta and epsilon receptors. J Pharmacol Exp Ther 246 1018-1025. 

Williams, M.E., Kullbeig, M.C., Barbieri, S., Caspar,, Ber-zo ky, J.A., Seder, R.A. and Sher, A. (1993). Fc epsilon receptor-positive cells are a major source of antigen-induced interleukin-4 in spleens of mice infected with Schistosoma mart-smi. Eur. J. Immunol. 23, 1910-1916. 

Seder, R,A., Paul, W.E., Dvorak, A.M., Sharkis, S.J., Kagey-Sobotka, A., Niv, Y., Finkelman, F.D., Barieri, S.A., Galli, S.J. and Plaut, M. (1991b). Mouse splenic and bone marrow preparation that express high-affinity epsilon receptor and produce interleukin 4 are highly enriched basophils. Proc. Natl. Acad. Sci. USA 88, 2836-2839. 

Munoz JJ, Peacock MG Action of pertussigen (pertussis toxin) on serum IgE and on Fc epsilon receptors on lymphocytes. Cell Immunol 1990 127 327-336. 

E. A. Padlan, B. A. Helm. Modeling of the lectin-homology domains of the human and murine low-affinity Fc epsilon receptor (Fc epsilon RII/CD23). Receptor. 1993, 3, 325—... 

Prieschl, E.E., Csonga, R. Novotny, V., Kikuchi, G.E., and Baumruker, T., The balance between sphingosine and sphingosine-l-phosphate is decisive for mast cell activation after Fc epsilon receptor I triggering. J Exp Med, 190 (1999) 1-8. 

Yokota A, Kikutani H, Tanaka T, Sato R, Barsumian EL, Suemura M, Kishimoto T. Two species of human Fc epsilon receptor II (FeRII/CD23) tissue-specific and IL-4-specific regulation of gene expression. Cell 1988 55 611-618. 

Yamaguchi M, Sayama K, Yano K, Lantz CS, Noben-Trauth N, Ra C, Costa JJ, Galli SJ. IgE enhances Fc epsilon receptor 1 expression and IgE-dependent release of histamine and lipid mediators from human umbilical cord blood-derived mast cells synergistic effect of IL-4 and IgE on human mast cell Fc epsilon receptor I expression and mediator release. J Immunol 1999 162 5455-5465. 

Xia HZ, Du Z, Craig S, Klisch G, Noben-Trauth N, Kochan JP, Huff TH, Irani AM, Schwartz LB. Effect of recombinant human IL-4 on tryptase, chymase, and Fc epsilon receptor type I expression in recombinant human stem cell factor-dependent fetal liver-derived human mast cells. J Immunol 1997 159 2911-2921. 

Kohler I, Rieber EP. AUergy-associated I epsilon and Ec epsilon receptor II (CD23b) genes activated via binding of an interleukin -induced transcription factor to a novel responsive element. Eur J Immunol 1993 23 3066-3071. 

Here, [R]T is the total concentration of receptors, and e (epsilon) is the intrinsic efficacy (not to be confused with intrinsic activity) e can be regarded as a measure of the contribution of individual receptors to the overall efficacy. 

Moragues, N., Ciofi, P., Lafon, P., Tramu, G., Garret, M. (2003). GABAa receptor epsilon subunit expression in identified peptidergic neurons of the rat hypothalamus. Brain Res. 967, 285-9. 

In this example, the relation between 19 chemicals and 23 physicochemical parameters was examined ( ). PLS, unlike canonical correlation, permits use of more chemical parameters than stimuli. The twenty-three physicochemical variables included molecular weight, functional groups, Raman frequencies and Laffort parameters (see ( )) The Laffort parameters are alpha (an apolar factor proportional to molvolume), rho (a proton receptor factor), epsilon (an electron factor) and pi (a proton donor factor). 

Ikeda, K., Nakasawa, M., Mori, H., Araki, K., Sakimura, K., Watanabe, M., Inoue, Y., Mishina, M. Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel, FEBS Lett. 1992, 313, 34-38. 

Kislinger T, Fu C, Huber B, Qu W, Taguchi A, Du Yan S, Hofmann M, Yan SF, Pischetsrieder M, Stern D, Schmidt AM. 1999. N(epsilon)-(carboxymethyl)lysine adducts of proteins are ligands for receptor for advanced glycation end products that activate cell signaling pathways and modulate gene expression. J Biol Chem 274(44) 31740-31749. 

Hill MR, Cookson WO. A new variant of the beta subunit of the high-affinity receptor for immunoglobulin E (Fc epsilon Rl-beta E237G) associations with measures of atopy and bronchial hyper-responsiveness. Hum Mol Genet 1996 5(7) 959-962. 

Sandford AJ, Shirakawa T, Moffatt MF, Daniels SE, Ra C, Faux JA, Young RP, Nakamura Y, Lathrop GM, Cookson WO. Localisation of atopy and beta subunit of high-affinity IgE receptor (Fc Epsilon RI) on chromosome llq. Lancet 1993 341(8841) 332-334. 

Lieb K, Biersack L, Waschbisch A, et al. Serotonin via 5-HT7 receptors activates p38 mitogen-activated protein kinase and protein kinase C epsilon resulting in interleukin-6 synthesis in human U373 MG astrocytoma cells. J Neurochem 2005 93 549-559. 

Si J, Wang Q, Mei L. 1999. Essential roles of c-JUN and c-JUN N-terminal kinase (JNK) in neuregulin-increased expression of the acetylcholine receptor epsilon-subunit. J Neurosci 19 8498-8508. 

Won S, Si J, Colledge M, Ravichandran KS, Froehner SC, et al. 1999. Neuregulin-increased expression of acetylcholine receptor epsilon-subunit gene requires ErbB interaction with She. J Neurochem 73 2358-2368. 

Wuster M, Schulz R, Herz A. 1979. Specificity of opioids towards the mu-, delta- and epsilon-opiate receptors. Neu-rosciLett 15 193-198. 

The 3 end of an intron and the 5 end of an exon carry a consensus sequence of CAG G, where the vertical line represents the intron/exon boundary. The AG dinucleotide is scanned from the branch point and the first AG is recognized as the 3 end of the intron (Chen et al 2000). In a patient with congenital myasthenic syndrome, we identified duplication of a 16-nt segment comprised of 8 intronic and 8 exonic nucleotides at the intron 10/exon 10 boundary of CHRNE encoding the acetylcholine receptor epsilon subunit (Ohno et al 2005). We found that the upstream AG of the duplicated segment is exclusively used for splicing and that one or two mutations in the upstream BPS had no effect whereas complete deletion of the upstream BPS partially activated the downstream AG. Similar exclusive activation of the upstream AG is reported in HEXB (Dlott et al., 1990) and SLC4A1 (Bianchi et al, 1997). Creation of a cryptic AG dinucleotide close to the 3 end of an intron should be carefully scrutinized in mutation analysis. 

CD3 complex of delta, epsilon, gamma, zeta and eta chains of integral membrane glycoproteins that associates with T cell antigen receptor (TCR), and is required for TCR cell surface expression and signal transduction. CDS is a universally expressed by T cells. Member of immunoglobulin superfamily. 

Kitamura T, Mishina M, Sugiyama H (2003) Enhancement of neurogenesis by running wheel exercises is suppressed in mice lacking NMDA receptor epsilon 1 subunit. Neurosci Res 47 55-63. 

Suzuki T, Okumura-Noji K (1995) NMDA receptor subunits epsilon 1 (NR2A) and epsilon 2 (NR2B) are substrates for Fyn in the postsynaptic density fraction isolated from the rat brain. Biochem Biophys Res Commun 216 582-588. 

HiU M, Beeson D, Moss P, Jacobson L, Bond A, Corlett L, Newsom-Davis J, Vincent A, WUlcox N. Early-onset myasthenia gravis a recurring T-cell epitope in the adult-specific acetylcholine receptor epsilon subunit presented by the susceptibility allele HLA-DR52a. Ann Neurol 1999 45(2) 224-31. 

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