Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Epoxidations asymmetric

Dioos, B. M. L. Jacobs P. A. (2005) Impregnation of dimeric Crlll(salen) on silica and its application in epoxides asymmetric ring opening reactions.. Applied Catalysis A General, 282 181-188. [Pg.343]

This chapter focuses on several recent topics of novel catalyst design with metal complexes on oxide surfaces for selective catalysis, such as stQbene epoxidation, asymmetric BINOL synthesis, shape-selective aUcene hydrogenation and selective benzene-to-phenol synthesis, which have been achieved by novel strategies for the creation of active structures at oxide surfaces such as surface isolation and creation of unsaturated Ru complexes, chiral self-dimerization of supported V complexes, molecular imprinting of supported Rh complexes, and in situ synthesis of Re clusters in zeolite pores (Figure 10.1). [Pg.375]

We began these studies with the intention of applying this tandem asymmetric epoxidation/asymmetric allylboration sequence towards the synthesis of D-olivose derivative 63 (refer to Figure 18). As the foregoing discussion indicates, our research has moved somewhat away from this goal and we have not yet had the opportunity to undertake this synthesis. This, as well as the synthesis of the olivomycin CDE trisaccharide, remain as problems for future exploration. Because it is the enantioselectivity of the tartrate ester allylboronates that has limited the success of the mismatched double asymmetric reactions discussed here, as well as in several other cases published from our laboratorythe focus of our work on chiral allyiboronate chemistry has shifted away from synthetic applications and towards the development of a more highly enantioselective chiral auxiliary. One such auxiliary has been developed, as described below. [Pg.266]

Asymmetric Epoxidation. Asymmetric epoxidation of nonfunctionalized alkenes manifests a great synthetic challenge. The most successful method of asymmetric epoxidation, developed by Katsuki and Sharpless,332 employs a Ti(IV) alkoxide [usually Ti(OisoPr)4], an optically active dialkyl tartrate, and tert-BuOOH. This procedure, however, was designed to convert allylic alcohols to epoxy alcohols, and the hydroxyl group plays a decisive role in attaining high degree of enantiofa-cial selectivity.333,334 Without such function, the asymmetric epoxidation of simple olefins has been only moderately successful 335... [Pg.460]

In addition, solid-phase bound short-chain peptides have been recently found by the Ber-kessel group to act as highly efficient catalysts in asymmetric epoxidation reactions [17]. In the early 1980s, Julia and Colonna reported that chalcone 11 can be epoxidized asymmetrically by akaline hydrogen peroxide in the presence of poly-amino acids as catalysts [18, 19], The work by Berkessel et al. revealed that in fact as little as five I-Leu residues are sufficient for the epoxidation of the enone 11 with 96-98% ee (Scheme 8). [Pg.184]

EPOXIDATION, ASYMMETRIC (- )-Benzylquininium chloride. f-Butyl hydroperoxide-Vanadyl acetoacetate. Hydrogen peroxide-1,1,3,3-Tetrachloro-acetone. (S)-(2-Hydroxy-N,N-dimethyl-propanamide-0,0 )oxodiperoxymolyb-denum(VI). [Pg.238]

JULI A-COLONNA Asymmetric Epoxidation Asymmetric epoxidation of electron-poor olefins catalyzed by poly-a amino acids. [Pg.180]

Epoxidation. Asymmetric epoxidation has been an active area of research, and many... [Pg.84]

There are many possible answers here. What we had in mind was some sort of asymmetric Diels-Alder reaction for the first, an asymmetric aldol for the second or else opening an epoxide made by Sharpless epoxidation, asymmetric dihydroxylation for the third, and perhaps asymmetric dihydroxylation of a 2-alkene for the fourth. Of course you might have used resolution or asymmetric hydrogenation, or the chiral pool, or any other strategy from chapter 41. [Pg.489]

In the total synthesis, the most noteworthy aspect is the philosophy of the approach. Also, the important point is not just the total yield, but, primarily the completion of the synthesis, as artists never exhibit their unfinished work and since a synthesis cannot be an Unfinished Symphony. Considering the many kinds of useful reactions which have been developed to serve as synthetic key steps, such as asymmetric epoxidation, asymmetric reduction and enantiospeci-fic aldol reaction using chiral reagents, and, considering the many kinds of enantiomerically pure materials such as carbohydrates which are available, any complex antibiotic may be synthesized. Consequently, a philosophy of synthesis is more urgently required than ever before. [Pg.36]

The original asymmetric synthesis has been extensively improved in modem organic synthesis, such as in the Sharpless Epoxidation, asymmetric hydrogenation, and enzymatic hydrolysis. [Pg.1830]

A number of insect pheromones are epoxides. Asymmetric hydrolysis of meso-diacetate 3 (Figure 24.2) witii pig pancreatic lipase (PPL) gives (2S,3P)-4-acetoxy-2, 3-epoxy-l-butanol (4, 90% ee) in 71% yield [4], Various epoxide pheromones were synthesized from (2S,3K)-4, which could be purified to give enantiopure material by recrystallizing tiie corresponding 3,5-dinitrobenzoate. [Pg.588]


See other pages where Epoxidations asymmetric is mentioned: [Pg.8]    [Pg.261]    [Pg.464]    [Pg.92]    [Pg.102]    [Pg.253]    [Pg.457]   
See also in sourсe #XX -- [ Pg.201 ]




SEARCH



2.4- Hexadien asymmetric epoxidation

AUyl alcohols asymmetric epoxidation

Acetals asymmetric epoxidation

Acyclic asymmetric epoxidation

Alcohols asymmetric epoxidation

Alcohols, alkynic asymmetric epoxidation

Aldehydes conjugated, asymmetric epoxidation

Alkenes Sharpless asymmetric epoxidation

Alkenes catalytic asymmetric epoxidation

Alkenes epoxidation, asymmetric

Allyl alcohols asymmetric epoxidation

Allyl asymmetric epoxidation

Allyl carbonates asymmetric epoxidation

Allylic alcohols Sharpless asymmetric epoxidation

Allylic alcohols Sharpless-Katsuki asymmetric epoxidation

Allylic alcohols asymmetric epoxidation

Allylic alcohols directed asymmetric epoxidations

Amine oxides asymmetric epoxidation

Amines, 3-hydroxy asymmetric epoxidation

Aryl asymmetric epoxidation with chiral

Asymmetric Desymmetrization of meso Epoxides

Asymmetric Epoxidation (AE) of Unfunctionalized Olefins

Asymmetric Epoxidation and Dihydroxylation

Asymmetric Epoxidation and Kinetic Resolution

Asymmetric Epoxidation of Aliphatic Alkenes

Asymmetric Epoxidation of Alkenes other than Allyl Alcohols

Asymmetric Epoxidation of Allylic Alcohols and Mechanisms

Asymmetric Epoxidation of Aromatic Alkenes

Asymmetric Epoxidation with Polymeric Cinchona-PTCs

Asymmetric Hydrolysis of Epoxides

Asymmetric Nucleophilic Epoxidation

Asymmetric epoxidation

Asymmetric epoxidation

Asymmetric epoxidation 1-substituted allyl alcohols

Asymmetric epoxidation 3 + 2] cycloaddition reactions

Asymmetric epoxidation Atom transfer reactions

Asymmetric epoxidation Jacobsen manganese

Asymmetric epoxidation Sharpless titanium

Asymmetric epoxidation absolute configuration

Asymmetric epoxidation alcohol-free dichloromethane

Asymmetric epoxidation allyl organometallics

Asymmetric epoxidation applications

Asymmetric epoxidation carbon-oxygen bond formation

Asymmetric epoxidation catalysis

Asymmetric epoxidation catalyst preparation

Asymmetric epoxidation catalytic cycle

Asymmetric epoxidation catalyzed by novel azacrown ether-type chiral quaternary ammonium salts under phase-transfer catalytic conditions

Asymmetric epoxidation chiral amines

Asymmetric epoxidation chiral hydroperoxides

Asymmetric epoxidation chiral metal complex catalysis

Asymmetric epoxidation chiral quaternary ammonium salts

Asymmetric epoxidation compatibility

Asymmetric epoxidation competing side reactions

Asymmetric epoxidation concentration

Asymmetric epoxidation conditions

Asymmetric epoxidation defined

Asymmetric epoxidation diastereoselectivity

Asymmetric epoxidation dioxirane-catalyzed epoxidations

Asymmetric epoxidation disubstituted £-alkenes

Asymmetric epoxidation double

Asymmetric epoxidation drug synthesis

Asymmetric epoxidation electron-deficient olefins

Asymmetric epoxidation electrophilic reactions

Asymmetric epoxidation enamides

Asymmetric epoxidation enantiofacial selectivity

Asymmetric epoxidation enantioselectivity

Asymmetric epoxidation enol ethers

Asymmetric epoxidation guanidines

Asymmetric epoxidation homogeneous catalysis

Asymmetric epoxidation ketones

Asymmetric epoxidation kinetics

Asymmetric epoxidation matched double

Asymmetric epoxidation mechanism

Asymmetric epoxidation methods

Asymmetric epoxidation mismatched double

Asymmetric epoxidation molecular sieves

Asymmetric epoxidation natural products synthesis

Asymmetric epoxidation nucleophilic epoxidations

Asymmetric epoxidation nucleophilic reactions

Asymmetric epoxidation of -undec-2-en-l-ol

Asymmetric epoxidation of 1-phenylcyclohexene

Asymmetric epoxidation of alkenes

Asymmetric epoxidation of swainsonine

Asymmetric epoxidation of terminal alkenes

Asymmetric epoxidation of unfunctionalized alkenes

Asymmetric epoxidation oxidant

Asymmetric epoxidation pharmaceutical products synthesis

Asymmetric epoxidation phase-transfer catalysis

Asymmetric epoxidation racemic synthesis

Asymmetric epoxidation radical addition reactions

Asymmetric epoxidation radical cyclizations

Asymmetric epoxidation radicals

Asymmetric epoxidation ratio of titanium to tartrate

Asymmetric epoxidation secondary amines

Asymmetric epoxidation solid support

Asymmetric epoxidation solvent

Asymmetric epoxidation stereoselective synthesis

Asymmetric epoxidation steroids

Asymmetric epoxidation stoichiometry

Asymmetric epoxidation substrate structure

Asymmetric epoxidation synthesis

Asymmetric epoxidation titanium complexes

Asymmetric epoxidation titanium tartrate catalysis

Asymmetric epoxidation total synthesis

Asymmetric epoxidation transition metal catalysts

Asymmetric epoxidation under phase-transfer catalytic

Asymmetric epoxidation using TPPP

Asymmetric epoxidation vanadium

Asymmetric epoxidation, Jacobsen

Asymmetric epoxidation, alken

Asymmetric epoxidation-ring

Asymmetric epoxidation-ring expansion

Asymmetric epoxide opening

Asymmetric epoxide synthesis

Asymmetric of meso epoxides

Asymmetric reactions epoxidation

Asymmetric synthesis Jacobsen-Katsuki epoxidation

Asymmetric synthesis Sharpless-Katsuki epoxidation

BINOLate/La -catalyzed asymmetric epoxidation

Carbonyl catalytic asymmetric epoxidation

Catalytic Asymmetric Epoxide Ring-opening Chemistry

Catalytic asymmetric anhydrous epoxidation

Catalytic asymmetric epoxidation

Chalcone derivatives, asymmetric epoxidation

Chiral epoxides, enantioselective asymmetric

Chiral hydroperoxides allylic alcohol asymmetric epoxidation

Chiral ketone-catalyzed asymmetric epoxidation

Chromium, asymmetric epoxidation

Cinnamyl alcohol asymmetric epoxidation

Claisen-Schmidt Condensation-Asymmetric Epoxidation

Complexes asymmetric epoxidation

Crown asymmetric epoxidation

Cumyl hydroperoxide asymmetric epoxidation

Dicyclododecyl tartrate asymmetric epoxidation

Dicyclohexyl tartrate asymmetric epoxidation

Diethyl tartrate asymmetric epoxidation

Dihydroisoquinolinium asymmetric epoxidation

Diisopropyl tartrate asymmetric epoxidation

Dimethyl tartrate asymmetric epoxidation

Diols Jacobsen asymmetric epoxidation

Diols, chlorosynthesis via asymmetric epoxidation

Dioxiranes, asymmetric olefin epoxidation

Electron asymmetric epoxidation

Enones asymmetric epoxidation, synthetic

Enones asymmetric epoxidations

Enones catalytic asymmetric epoxidation

Epoxidation organocatalytic, asymmetric

Epoxidations, asymmetric chiral ketone-catalyzed

Epoxidations, catalytic asymmetric

Epoxide asymmetric ring-opening

Epoxide hydrolysis, asymmetric

Epoxides Jacobsen-Katsuki asymmetric synthesis

Epoxides Sharpless-Katsuki asymmetric synthesi

Epoxides asymmetric

Epoxides asymmetric epoxidation

Epoxides asymmetric epoxidation

Epoxides asymmetric fluorination

Epoxides asymmetric phase-transfer

Epoxides asymmetric ring-opening

Epoxides, asymmetric synthesis

Epoxides, ring-opening, asymmetric synthesis

Esters asymmetric epoxidation

Ethers asymmetric epoxidation

Fructose ketone derivatives, asymmetric olefin epoxidation

Furan, 2,5-dimethoxy-2,5-dihydroSubject asymmetric epoxidation

Furanols asymmetric epoxidation

Geraniol: asymmetric epoxidation

Heterogeneous asymmetric catalysis epoxidation

Homoallyl alcohols asymmetric epoxidation

Homoallylic alcohols asymmetric epoxidation

Iminium salt-mediated catalytic asymmetric epoxidation

In Sharpless asymmetric epoxidation

Indene, asymmetric epoxidation with

Iron asymmetric epoxidation

Iron-Catalyzed Asymmetric Epoxidations

JACOBSEN ASYMMETRIC RING-OPENING OF EPOXIDES

JULIA-COLONNA Asymmetric Epoxidation

Jacobsen-Katsuki asymmetric epoxidation

Ketals asymmetric epoxidation

Ketone-catalyzed asymmetric epoxidation

Ketones asymmetric olefin epoxidation

Manganese asymmetric epoxidation

Manganese-catalyzed Asymmetric Epoxidations

Model asymmetric epoxidation

Natural products asymmetric olefin epoxidation

Non-asymmetric epoxidation

Novel Heterogenized Catalysts for Asymmetric Ring-Opening Reactions of Epoxides

Nucleophiles asymmetric epoxidations

Olefin epoxidation, asymmetric catalysis

Olefins asymmetric epoxidation

Organocatalytic Oxidation. Ketone-Catalyzed Asymmetric Epoxidation of Alkenes and Synthetic Applications

Organocatalytic Oxidation. Ketone-catalyzed Asymmetric Epoxidation of Olefins

Oxidation Sharpless-Katsuki asymmetric epoxidation

Oxidation reactions asymmetric epoxidation

Oxidation reactions, transition-metal asymmetric epoxidation

Oxiranemethanol, 2-methylsynthesis via asymmetric epoxidation

Oxone, asymmetric olefin epoxidation

Phenols asymmetric epoxidation

Polymeric asymmetric epoxidation

Pore asymmetric epoxidation

Propranolol Sharpless asymmetric epoxidation

Reactions catalytic asymmetric epoxidation

Regioselectivity asymmetric epoxidation

SHARPLESS Asymmetric epoxidation

Sharpless asymmetric epoxidation Catalyst structure

Sharpless asymmetric epoxidation Claisen

Sharpless asymmetric epoxidation Kinetic resolution using

Sharpless asymmetric epoxidation Propranolol synthesis

Sharpless asymmetric epoxidation Synthesis

Sharpless asymmetric epoxidation anionic oxy-Cope

Sharpless asymmetric epoxidation dihydroxylation

Sharpless asymmetric epoxidation directed epoxidations

Sharpless asymmetric epoxidation examples

Sharpless asymmetric epoxidation natural products synthesis

Sharpless asymmetric epoxidation of allylic alcohol

Sharpless asymmetric epoxidation of allylic amine oxides

Sharpless asymmetric epoxidation of allylic ethers

Sharpless asymmetric epoxidation of allylic selenoxides

Sharpless asymmetric epoxidation of allylic sulfonium ylides

Sharpless asymmetric epoxidation of allylic sulfoxides

Sharpless asymmetric epoxidation of ammonium ylides

Sharpless asymmetric epoxidation of ester silyl enol ethers

Sharpless asymmetric epoxidation of unsaturated iminium ions

Sharpless asymmetric epoxidation oxy-Cope

Sharpless asymmetric epoxidation process

Sharpless asymmetric epoxidation reaction

Sharpless asymmetric epoxidation stereochemistry

Sharpless asymmetric epoxidation stereoselectivity

Sharpless asymmetric epoxidation substituent effects

Sharpless asymmetric epoxidation titanium catalysts

Sharpless asymmetric epoxidations

Sharpless kinetic asymmetric epoxidation

Sharpless-Katsuki asymmetric epoxidation

Sharpless-Katsuki asymmetric epoxidation Mechanism

Sharpless-Katsuki asymmetric epoxidation Synthetic Utility

Shi asymmetric epoxidation

Styrene epoxide, asymmetric synthesis

Styrenes asymmetric epoxidation

Substituted alkenes, asymmetric epoxidation

Sulfides asymmetric epoxidations

Tartramide, dibenzylcatalyst asymmetric epoxidation

Tartrates asymmetric epoxidation

The Jacobsen asymmetric epoxidation

The Sharpless Asymmetric Epoxidation

Ti/tartrate-catalyzed asymmetric epoxidation

Titanium Tetraisopropoxide asymmetric epoxidation reactions

Titanium alkoxides asymmetric epoxidation

Titanium asymmetric epoxidation

Titanium asymmetric epoxidations

Titanium catalysts asymmetric epoxidation

Titanium complexes (Sharpless Ti tartrate asymmetric epoxidation catalyst)

Titanium compounds asymmetric epoxidation

Titanium isopropoxide asymmetric epoxidation

Titanium tartramide complexes asymmetric epoxidation

Titanium tartrate asymmetric epoxidation

Titanium tartrate asymmetric epoxidation, mechanism

Titanium tartrate asymmetric epoxidation, reaction variables

Trans-Disubstituted alkenes asymmetric epoxidation

Transition asymmetric epoxidation

Trishomoallylic alcohol asymmetric epoxidation

Trisubstituted alkenes asymmetric epoxidation

Triterpenes asymmetric epoxidation

Trityl hydroperoxide asymmetric epoxidation

Vanadium catalysts allylic alcohol asymmetric epoxidation

Vanadium catalysts asymmetric epoxidation

Zeolites asymmetric epoxidation

Zirconium isopropoxide asymmetric epoxidation

© 2024 chempedia.info