Electron capture atmospheric pressure chemical ionization

Lee SH, Blair lA. Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/ MS). Methods Enzymol 2007 433 159-174. [Pg.677]

Higashi, T. Yamauchi, A. Shimada, K. Application of 4-(4-nitrophenyl)-l,2,4-triazoline-3,5-dione to analysis of 25-hydroxyvitamin D3 in human plasma by hquid chroma-tography/electron capture atmospheric pressure chemical ionization-mass spectrometry. Anal. Sci. 2003, 19 (6), 941-943. [Pg.232]

Today, electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) are considered the standard ionization techniques for LC-MS/MS due to their predominant advantages in quantitative analysis of drug molecules in various sample matrices with high sensitivity, selectivity, reliability, robustness, and ease of operation. Other techniques, for example, atmospheric pressure photoionization (APPI), electron capture atmospheric pressure chemical ionization (EC-APCI), and high-field asymmetric waveform ion mobility mass spectrometry (FAIMS) serve as complements to the established ESI and/or APCI technical platforms whenever necessary for an enhanced sensitivity and/or selectivity of a bioanalytical assay [4,5]. [Pg.173]

Lee, S.H., Williams, M.V., DuBois, R.N. and Blair, LA. (2003) Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Com-mun. Mass Spectrom. 17, 2168-2176. [Pg.19]

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... [Pg.11]

ECD = electron capture detector FID = flame ionization detector GC = gas chromatography HRGC = high resolution gas chromatography LC-APCI-MS = liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry LSE = liquid-solid extraction MS = mass spectrometry PVC = polyvinyl chloride SFE = supercritical fluid extraction... [Pg.235]

In the 1980s Shuie, D sa, Limero, Gigi Bear, and Bernard White were the doctoral students at Wentworth. The latter two studied negative ions in flames. Master s student Hernandez examined the response of the ECD at short reaction times. Limero studied fluorobenzenes. D sa discovered a fourth temperature region in the ECD for chloro and bromoethylenes. Limero, D sa, and Shuie researched electron capture in the atmospheric pressure chemical ionization system and obtained data for anion complexes using such equipment. Batten became intimately involved with this work. Lee and R. Ranatunga, the doctoral students of Zlatkis, made additional contributions. [Pg.42]

APCI=atmospheric pressure chemical ionization AOAC=Association of Offical Analytical Chemists CaCl2=calciurn chioride cl=chemical ionization EC=electrochemical detection ECD=electron capture detection ED=electrochemical detection FID=flame ionization detection GC=gas chromatography ... [Pg.85]

Suitable analytes exhibit high electron capture capacity or high electron affinity. Cl is the technique of choice for the analysis of isomers in environmental samples. In APCI (Atmospheric Pressure Chemical Ionization) solvent evaporation and analyte ionization are two separate processes. [Pg.209]

Chemical ionization is an ionization mechanism that allows the formation of protonated or deprotonated molecules via a gas-phase ion—molecule reaction. It exists under two different forms one under vacuum (Cl) and the second one at atmospheric pressure referenced as atmospheric pressure chemical ionization (APCI). The principal difference between Cl and El mode is the presence of reagent gas, which is typically methane, isobutene, or ammonia (Mimson, 2000). The electrons ionize the gas to form the radical cations (in the case of methane, CH4 -I- e CH4 -I- 2e ). In positive chemical ionization (PCI), the radical cations undergo various ion—molecule reactions to form CHs and finally lead to the formation, after proton transfer (CHs + M [M + H] ), of protonated molecules. Negative chemical ionization (NCI) (Budzikiewicz, 1986), after proton abstraction, leads to the formation of deprotonated molecules [M — H] . Negative ions can be produced by different processes such as by capture of low-energy electrons present in the chemical ionization... [Pg.267]

G Tang, BA Andrien, GG Dolnikowski, RM RusseU. Atmospheric pressure chemical ionization and electron capture negative chemical ionization mass spectrometry... [Pg.83]