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Lipidomics analysis

D1 (10,17S-docosatriene) from DHA using tandem liquid chromatography-photodiode array-electrospray ionization-tandem mass spectrometry (LC-PDA-ESI-MS-MS)-based lipidomic analysis have been documented in ischemic brain [4] and retinal pigment epithelium [5], This new lipid is called neuroprotectin D1 (1) because of its neuro-protectiveproperties in brain ischemia-reperfusion [4] and in oxidative stress-challenged retinal pigment epithelial cells [5] (2) because of its potent ability to inactivate proapoptotic signaling (see apoptosis, Ch. 35) [5] and (3) because it is the first identified neuroprotective mediator derived from DHA. [Pg.577]

FIGURE 1 Total ion chromatogram from UHPLC-TOFMS lipidomics analysis of serum showing chromatographic separation of major lipid classes using ESI+ mode (for more details,... [Pg.387]

Astarita, G., and Piomelli, D. (2009). Lipidomic analysis of endocannabinoid metabolism in biological samples. J. Chromatogr. BAnalyt. Technol. Bicrmed. Life Sci. [Epub ahead of print]. [Pg.51]

Yetukuri L, Katajamaa M, Medina-Gomez G, Seppanen-Laakso T, Vidal-Puig A, Oresic M. Bioinformatics strategies for lipidomics analysis characterization of obesity related hepatic steatosis. BMC Syst. Biol. 2007 1 12-26. http //www.lipidlibmry.co.uk/lipids.html... [Pg.932]

Figure 2.2 Scan types utilized in lipidomic analysis by ESl-MS/MS. An MS/MS instrument consists of an initial mass (m/z) analyzer (MSi), a collision cell, and a second mass (m/z) analyzer (MSj). The two mass (m/z) analyzers and collision cell are separated in space on a beam instrument, such as tandem quadrupoles and Q-TOFs, and in time in ion traps. Product-ion, precursor-ion, and neutral-loss scans are performed by respectively scanning MSj, MSj, or MSj and MS2 in parallel. Multiple reaction monitoring (MRM) chromatograms are recorded with MSj and MSj fixed for transitions of interest. MS or MS/MS/MS spectra are recorded when a third mass (m/z) analyzer MS3 is utilized following a second collision cell. MS and further MS" spectra are often recorded on ion-trap instruments. Figure 2.2 Scan types utilized in lipidomic analysis by ESl-MS/MS. An MS/MS instrument consists of an initial mass (m/z) analyzer (MSi), a collision cell, and a second mass (m/z) analyzer (MSj). The two mass (m/z) analyzers and collision cell are separated in space on a beam instrument, such as tandem quadrupoles and Q-TOFs, and in time in ion traps. Product-ion, precursor-ion, and neutral-loss scans are performed by respectively scanning MSj, MSj, or MSj and MS2 in parallel. Multiple reaction monitoring (MRM) chromatograms are recorded with MSj and MSj fixed for transitions of interest. MS or MS/MS/MS spectra are recorded when a third mass (m/z) analyzer MS3 is utilized following a second collision cell. MS and further MS" spectra are often recorded on ion-trap instruments.
Figure 2.15 MS spectrum (532->453->) of GP-tagged 24S,25-epoxycholesterol. The spectrum was recorded on an LTQ Orbitrap XL. (Reproduced with permission from Wang, Y. et al, 2009, Targeted Lipidomic Analysis of Oxysterols in the Embryonic Central Nervous System, Mol. Biosyst. May 5 529-41.)... Figure 2.15 MS spectrum (532->453->) of GP-tagged 24S,25-epoxycholesterol. The spectrum was recorded on an LTQ Orbitrap XL. (Reproduced with permission from Wang, Y. et al, 2009, Targeted Lipidomic Analysis of Oxysterols in the Embryonic Central Nervous System, Mol. Biosyst. May 5 529-41.)...
Christie, W. W. and Han, X. 2010. Lipid Analysis—Isolation, Separation, Identification and Lipidomic Analysis. Bridgewater, England The Oily Press Lipid Library. [Pg.77]

A. J. White, A. M. Dart, S. J. Duffy, G. L. Jennings, and B. A. Kingwell, Plasma lipidomics analysis of stable and unstable coronary artery disease, Arterioscler. Thromb. Vase. Biol. 31 2723-2732 (2011). [Pg.225]

Gruber, F., Bicker, W., Oskolkova, O. V., Tschachler, E., and Bochkov, V. N. 2012. A simplified procedure for semi-targeted lipidomic analysis of oxidized phosphatidylchohnes induced by UVA irradiation. 53,1232-42. [Pg.18]

Lee SH, Blair lA. Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/ MS). Methods Enzymol 2007 433 159-174. [Pg.677]

Lee SH, Williams MV, Blair I A. Targeted chiral lipidomics analysis. Prostaglandins Other Lipid Mediat 2005c 77 141-157. [Pg.678]

Dumlao, D.S., Buczynski, M.W., Norris, P.C., Harkewicz, R., and Dennis, E.A. (2011) High-throughput lipidomic analysis of fatty acid derived eicosanoids and N-acylethanolamines. Biochim. Bio-phys. Acta, 1811 (11), 724-736. doi 10.1016/j.bbalip.2011.06.005... [Pg.60]

Kien, C. L., Bimn, J. Y., Poynter, M. E., Stevens, R., Bain, J., Ikayeva, 0., et al. (2013). A lipidomics analysis of the relationship between dietary fatty acid composition and insulin sensitivity in young adults. Diabetes, 62(4), 1054-1063. [Pg.50]

Henderson, G. M., Lozada-Conteras, M., Jiranek, V., Longo, M. L., Block, D. E. (2013). Ethanol production and maximum cell growth are highly correlated with membrane lipid composition during fermentation as determined by lipidomic analysis of 22 Saccharomy-ces cerevisiae strains. Applied and Environmental Microbiology, 79, 91-104. [Pg.468]

Yang, K., Jenkins, C.M., Dilthey, B. and Gross, R.W. (2015) Multidimensional mass spectrometry-based shotgun lipidomics analysis of vinyl ether diglyceiides. Anal. Bioanal. Chem. 407, 5199-5210. [Pg.16]

Kishimoto, K., Urade, R., Ogawa, T. and Moriyama, T. (2001) Nondestructive quantification of neutral lipids by thin-layer chromatography and laser-fluorescent scanning Suitable methods for "lipidome" analysis. Biochem. Biophys. Res. Commun. 281, 657-662. [Pg.17]

Wang, M., Fang, H. and Han, X. (2012) Shotgun lipidomics analysis of 4-hydroxyalkenal species directly from Upid extracts after one-step in situ derivatization. Anal. Chem. 84, 4580-4586. [Pg.46]

Lobasso, S., Lopalco, P., Angelini, R., Baronio, M., Fanizzi, F.P., Babudri, F. and Corcelli, A. (2010) Lipidomic analysis of porcine olfactory epithelial membranes and ciHa. Lipids 45, 593-602. [Pg.47]

See other pages where Lipidomics analysis is mentioned: [Pg.587]    [Pg.588]    [Pg.266]    [Pg.36]    [Pg.40]    [Pg.40]    [Pg.40]    [Pg.41]    [Pg.42]    [Pg.44]    [Pg.46]    [Pg.48]    [Pg.48]    [Pg.50]    [Pg.51]    [Pg.52]    [Pg.54]    [Pg.56]    [Pg.499]    [Pg.932]    [Pg.946]    [Pg.412]    [Pg.440]    [Pg.606]    [Pg.394]    [Pg.396]    [Pg.88]    [Pg.79]    [Pg.144]    [Pg.14]   
See also in sourсe #XX -- [ Pg.39 ]



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