Electron-capture atmospheric

Lee SH, Blair lA. Targeted chiral lipidomics analysis by liquid chromatography electron capture atmospheric pressure chemical ionization mass spectrometry (LC-ECAPCI/ MS). Methods Enzymol 2007 433 159-174. 

Singh, G. Gutierrez, A. Xu, K. Blair, LA. Liquid chroma-tography/electron capture atmospheric pressure chemical... 

Higashi, T. Yamauchi, A. Shimada, K. Application of 4-(4-nitrophenyl)-l,2,4-triazoline-3,5-dione to analysis of 25-hydroxyvitamin D3 in human plasma by hquid chroma-tography/electron capture atmospheric pressure chemical ionization-mass spectrometry. Anal. Sci. 2003, 19 (6), 941-943. 

Today, electrospray ionization (ESI) and atmospheric pressure chemical ionization (APCI) are considered the standard ionization techniques for LC-MS/MS due to their predominant advantages in quantitative analysis of drug molecules in various sample matrices with high sensitivity, selectivity, reliability, robustness, and ease of operation. Other techniques, for example, atmospheric pressure photoionization (APPI), electron capture atmospheric pressure chemical ionization (EC-APCI), and high-field asymmetric waveform ion mobility mass spectrometry (FAIMS) serve as complements to the established ESI and/or APCI technical platforms whenever necessary for an enhanced sensitivity and/or selectivity of a bioanalytical assay [4,5]. 

Lee, S.H., Williams, M.V., DuBois, R.N. and Blair, LA. (2003) Targeted lipidomics using electron capture atmospheric pressure chemical ionization mass spectrometry. Rapid Com-mun. Mass Spectrom. 17, 2168-2176. 

Song LG, Wellman AD, Yao HF, Adcock J. Electron capture atmospheric pressure photoionization mass spectrometry analysis of fullerenes, perfluorinated compounds, and pentafluorobenzyl derivatives. Rapid Comm Mass Spec 2007 21(8) 1343—51. 

DGE a AC AMS APCI API AP-MALDI APPI ASAP BIRD c CAD CE CF CF-FAB Cl CID cw CZE Da DAPCI DART DC DE DESI DIOS DTIMS EC ECD El ELDI EM ESI ETD eV f FAB FAIMS FD FI FT FTICR two-dimensional gel electrophoresis atto, 10 18 alternating current accelerator mass spectrometry atmospheric pressure chemical ionization atmospheric pressure ionization atmospheric pressure matrix-assisted laser desorption/ionization atmospheric pressure photoionization atmospheric-pressure solids analysis probe blackbody infrared radiative dissociation centi, 10-2 collision-activated dissociation capillary electrophoresis continuous flow continuous flow fast atom bombardment chemical ionization collision-induced dissociation continuous wave capillary zone electrophoresis dalton desorption atmospheric pressure chemical ionization direct analysis in real time direct current delayed extraction desorption electrospray ionization desorption/ionization on silicon drift tube ion mobility spectrometry electrochromatography electron capture dissociation electron ionization electrospray-assisted laser desorption/ionization electron multiplier electrospray ionization electron transfer dissociation electron volt femto, 1CT15 fast atom bombardment field asymmetric waveform ion mobility spectrometry field desorption field ionization Fourier transform Fourier transform ion cyclotron resonance... 

Neumayr [3] carried out soil atmosphere studies using capillary gas chromatography and electron capture and flame ionization sequential detection and used this as a means of pinpointing zones of soil and groundwater contamination. 

Neumayr [3] has discussed methods for sampling soil atmospheres and gives a detailed account of gas chromatographic methods employing electron capture and flame ionization detectors for detecting and estimating specific components of the soil atmosphere. 

EPA. 1988g. Method T03. Method for the determination of volatile organic compounds in ambient air using cryogenic preconcentration techniques and GC with flame ionization and electron capture detection. Compendium of methods for the determination of toxic organic compounds in ambient air. Atmospheric Research and Exposure Assessment Laboratory, Office of Research and Development, U.S. Environmental Protection Agency, RTP, NC. EPA/600/4-89/017. 

Figure 1. Electron capture APIMS spectra of C7p,4 in pure nitrogen buffer gas (a) at atmospheric pressure and 150 °C, (b) with 13 torr of methanol (S) added to the nitrogen buffer gas at 150 °C, and (c) with 13 torr of methanol added to nitrogen buffer gas at 40 °C. From Reference 25.

We have recently described another spectroscopic rnethod for observing IM reactions at atmospheric pressure that utilizes the photodetachment-modulated electron capture detector (PDM-ECD) as a means of monitoring the negative ions either consumed or produced in an IM reaction. The reaction of interest is made to occiu in a steady-state flow-through reactor in which ionization of the buffer gas is continuously caused by a Ni-on-Pt foil beta emitter. A chopped light beam of... 

Figure 4, Structure of a series of alkyl bromides and the rate constants (1 O " cm s ) for the IM reaction of each compound with the chloride ion, determined by the photodetachment-modulated electron capture detector (PDM-ECD) in 10% argon-inmethane buffer gas at atmospheric pressure and 125 °C. ...

The formation and fate of peroxyacyl nitrates, RC(0)00N02, were discussed in Chapter 6.1. These compounds are almost universally measured using gas chromatography with electron capture detection (GC-ECD), although a luminol chemiluminescence detector has also been used in which PAN is thermally decomposed to N02 at the end of the column and the N02 measured (Burkhardt et al., 1988 Blanchard et al., 1990 Gaffney et al., 1998). In polluted atmospheres where the concentrations are higher, FTIR has also been used (Table 11.2). For a summary of methods, see reviews by Gaffney et al. (1989) and Kleindienst (1994). 

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