Antibody dependent cell cytotoxicity

See, D.M. et al., In vitro effects of echinacea and ginseng on natural killer and antibody-dependent cell cytotoxicity in healthy subjects and chronic fatigue syndrome or acquired immunodeficiency syndrome patients, Immunopharmacology, 35, 229, 1997. 

NE NK activity Antibody-Dependent Cell Cytotoxicity (ADCC) Decrease Decrease... 

Halothane-induced hepatitis seems to be mediated by both humoral and cell-mediated aspects of the immune system. Thus, both specific circulating antibodies and cytotoxic T lymphocytes are involved. One suggestion is that the mechanism involves antibody-dependent cell cytotoxicity (ADCC). 

ADCC antibody-dependent cell cytotoxicity, adenocarcinoma malignant epithelial tumor, adenoma benign epithelial tumor of glandular origin. 

Halothane. Anaesthetic drug which causes hepatic damage. Mild hepatic dysfunction is common. Occasionally serious hepatic necrosis occurs which is an idiosyncratic reaction (factors multiple exposures sex—female> male obesity history of allergy). A reactive metabolite is produced which binds to hepatocyte protein (microsomal) and stimulates an immunological reaction involving T-lymphocytes and antibodies (Antibody-Dependent Cell Cytotoxicity). Hepatocytes are destroyed by lymphocyte-mediated cytolysis. 

Covering of antigenic determinants by specific antibodies on target cells, followed by deleterious effects brought about by cytotoxic T-lymphocytes (antibody-dependent cell cytotoxicity). 

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