Ointments antiseptics

Cationic surfactants are also the basis of commonly used antiseptic ointments - see box. 

Use Surgical dusting powder, antiseptic ointment, fungicide. 

The mouse is put under red light for 10 to 20 minute before the blood drawing to promote the blood circulation. Then, the animal is inserted into a mouse block (Bio-Tec, Basel) and a maximum of 100 J.l of blood is taken through a cut in the tail. Antiseptic ointment is applied to the cut after the blood drawing. 

Products and Uses Useful as an antibacterial, antiseptic ointment, suppositories, throat lozenges, and other pharmaceuticals. Used in assorted medical products as an antimicrobial. 

Bacitracin, extracted from B, subtilis, is a decapeptide containing four D-amino acid residues and a thiazoline nucleus. Its point of attack is the formation of a complex with the sugar-transporting undecaprenyl pyrophosphate in the plasma membrane, an early stage in cell-wall synthesis briefly referred to in Section 5.3 (Stone and Strominger, 1971). Too nephrotoxic for internal use, bacitracin is a valuable constituent of antiseptic ointments. It requires a divalent metal for its attack (Section 11.9). 

Both German chamomile and Roman chamomile extracts are used in pharmaceutical preparations, with the former more frequently used they are used in antiseptic ointments, creams, and gels to treat cracked nipples, sore gums, inflammations, irritation of the skin and mucosa, respiratory tract inflammation, and for wound healing. The volatile oils are used in carminative, anti-spasmodic, and tonic preparations, among others. An infusion or tincture of the flower-heads is used for gastrointestinal spasms, inflammatory conditions of the gastrointestinal tract, and peptic ulcers, menstrual disorders, in addition to mild sleep disorders, especially in children (bradly Escop 1 wichtl). ... 

Among the several lavender products, lavender oil is usually the one used in pharmaceuticals it is used as a fragrance component in products such as antiseptic ointments, creams, lotions, and jellies, among others. 

Med. Use Has been recommended as a surgical dusting powder and as an antiseptic ointment. 

Apart from its usage in bakery, cooking, confectionery, toothpastes and dentifrices, perfumes, cosmetics and on toothpicks, oil of cinnamon may be incorporated in proprietary medicines. Calnan(57 ) reported 6 patients with an allergic contact dermatitis from the use of a proprietary antiseptic ointment (TCP ointment), containing oil of cinnamon. Three were positive and three negative to balsam of Peru. Two of the latter cases and one other also reacted to cinnamic aldehyde. 

Zinc carbonate and zinc oxide are constituents of calamine lotion. Zinc oxide, an antiseptic, is present in zinc ointment and in cosmetic powders. 

Sahcyhc acid USP, EP, and other pharmacopeia grades are used medically as antiseptic, disinfectant, antifungal, and keratolytic agents. Sahcyhc acid is formulated in lotion or ointment formulations for the treatment of dandmff, eczema, psoriasis, and various parasitic skin diseases. Because the keratolytic property of this aromatic acid has use in the safe removal of dead skin cells from the surface of healthy skin, the acid is used in concentrated sahcyhc acid solutions or suspensions to remove warts and corns. In more dilute form, sahcyhc acid preparations have found use in dandmff and eczema treatment. Sahcyhc acid has been considered and found effective by the Advisory Committees to the FDA in various over-the-counter (OTC) dmg regulated uses. Among these are acne products, dermatitis, dry skin, dandmff and psoriasis products, and foot care products (24). 

Sorbitan sesquioleate emulsions of petrolatum and wax are used as ointment vehicles in skin treatment. In topical appHcations, the inclusion of both sorbitan fatty esters and their poly(oxyethylene) derivatives modifies the rate of release and promotes the absorption of antibiotics, antiseptics, local anesthetics, vasoconstrictors, and other medications from suppositories, ointments, and lotions. Poly(oxyethylene(20)) sorbitan monooleate, also known as Polysorbate 80 (USP 23), has been used to promote absorption of ingested fats from the intestine (245). 

In medicine, the internal uses of benzoic acid are relatively unimportant. Its principal medicinal use is external it is used in dermatology as an antiseptic stimulant and irritant. Combined with salicyLic acid [69-72-7] benzoic acid is employed in the treatment of ringworm of the scalp and other skin diseases (Whitfield s ointment). 

The NF and reagent grades are employed in the pharmaceutical industry which makes use of benzyl alcohol s local anesthetic, antiseptic, and solvent properties (17—20). It also finds use in cough symps and drops ophthalmic solutions bum, dental (21), and insect repeUant solutions and ointments and dermatological aerosol sprays. It is used in nail lacquers and as a color developer in hair dyes by the cosmetics industry (22), and in acne treatment preparations (23). 

After the tape mask removal the exudate is cleaned by sterile saline. Spot peeling and retaping may be done if the skin looks underpeeled, particularly in areas with severe wrinkling. It is usually accompanied by a short-duration burning sensation. The tape is left for an additional 4-6 h and then removed by the patient. We cover the face with bismuth subgalate antiseptic powder for 7 days (Fig. 8.10). Other options include occlusive moisturizers, antibiotic ointments, and biosynthetic occlusive dressings such as Meshed Omiderm. 

Dermal exposure also occurs through the use of phenol-containing ointments, ear and nose drops, analgesic rubs (Douglas 1972), and antiseptic lotions (Musto et al. 1977). It is not possible to estimate dose levels for these sources given the available data. 

Uses Removal of granulation tissue warts prophylaxis in bums Action Caustic antiseptic astringent Dose Adults Peds. Apply to moist surface 2-3 x wk for several wk or until effect Caution [C, ] Contra Do not use on broken skin Disp Topical impregnated applicator sticks, soln ophth topical ointment SE May stain tissue black, usually resolves local irritation, methemoglobinemia EMS None OD Unlikely... 

Boric acid is used as an antiseptic in mouthwashes, eye washes, and ointments a preservative in natural products to protect wood against insect damage in washing citrus fruits as a catalyst in hydrocarbon oxidation as a flame retardant in cellulose insulation in nickel electroplating baths and as a buffer in ammonia analysis of wastewaters hy acid titration. 

Mercury(II) oxide is found natively in the mineral montroydite. The oxide is used primarily to prepare other mercury salts. The red form of the oxide is used as a depolarizer in a certain type of dry batteries. Other applications are paints and pigments as a reagent in several wet analyses and to catalyze in organic reactions. The oxide also is used in ointments as a topical antiseptic. 

Also, it is used in lotions, ointments, cosmetics, and as a topical antiseptic. Physical Properties... 

The dosage forms applied locally to the skin are powders, paste, lotions, ointments, creams, plasters and jellies. They are used for their antiseptic, antipruritic, analgesic, local anaesthetic and other related effects. 

Ointments are semi-solid greasy preparation for local application to the skin, rectum and mucous membrane also. The ointment base is usually anhydrous and contain the medicaments in solution or suspension. Ointments are used for its soothing, astringent, antiseptic and other selected actions e.g. Chloromycetin eye ointment. 

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