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Alpha-interferon hepatitis treatment

Schalm, S.W., Heathcote, X, Ciandara, X, Farrell, G., Sherman, M., Willems, B., Dhillon, A., Moorat, A., Barber, X, Gray, D.F. Lamivudine and alpha interferon combination treatment of patients with chronic hepatitis B infection a randomized trial. Gut 2000 46 562-568... [Pg.713]

Hong SH, Cho O, Kim K, Shin HJ, Kotenko SV, Park S (2007) Effect of interferon-lambda on replication of hepatitis B virus in human hepatoma cells. Virus Res 126 245-249 Hoofnagle JH, Mullen KD, Jones DB, Rustgi V, Di BiscegUe A, Peters M, Waggoner JG, Park Y, Jones EA (1986) Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon. A preliminary report. N Engl J Med 315 1575-1578 Horiike N, Onji M (2003) Combination therapy with interferon-alpha and ribavirin as im-munomodulators in patients with chronic hepatitis C. J Gastroenterol 38 302-304... [Pg.234]

Munoz R, Castellano G, Eernandez I, Alvarez MV, Manzano ML, Marcos MS, Cuenca B, Solis-Herruzo JA (2002) A pilot study of beta-interferon for treatment of patients with chronic hepatitis B who failed to respond to alpha-interferon, J Hepatol 37 655-659... [Pg.237]

Peters M, Waiting DM, Kelly K, Davis GL, Waggoner JG, Hoofnagle JH (1986) Immunologic effects of interferon-alpha in man treatment with human recombinant interferon-alpha suppresses in vitro immunoglobulin production in patients with chronic type B hepatitis. J Immunol 137 3147-3152... [Pg.239]

Wolters LM, van Nunen AB, Honkoop P, Vossen AC, Niesters HG, Zondervan PE, de Man RA (2000) Lamivudine-high dose interferon combination therapy for chronic hepatitis B patients co-infected with the hepatitis D virus. J Viral Hepat 7 428 34 Wong DK, Cheung AM, O Rourke K, Naylor CD, Detsky AS, Heathcote J (1993) Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B. A metaanalysis. Ann Intern Med 119 312-323... [Pg.242]

Woo, M. and Burnakis, T. 1997. Interferon-alpha in the treatment of chronic viral hepatitis-B and viral hepatitis... [Pg.239]

C. D. Naylor, A.S. Detsky, and 1. Heathcote, Effect of alpha-interferon treatment in patients with hepatitis B e antigen-positive chronic hepatitis B a meta-analysis. Ann Intern Med, 1993.119 312-23. [Pg.184]

Hoofnagle, J.H., K.D. Mnllen, D.B. Jones, et al.. Treatment of chronic non-A, non-B hepatitis with recombinant human alpha interferon a preliminary report. New Engl J Med, 1986. 315 1575-8. [Pg.184]

Schmitt K, Hompesch BC, Oeland K, von Staehr WG, Thurmann PA. Autoimmune thyroiditis and myelosup-pression following treatment with interferon-alpha for hepatitis C. Int J Clin Pharmacol Ther 1999 37(4) 165—7. [Pg.672]

Adinolfi, L.E., Utili, R., Tonziello, A., Rn ero, G. Effects of alpha interferon induction plus ribavirin with or without amantadine in the treatment of interferon nonresponsive chronic hepatitis C a randomized trial. Gut 2003 52 701 -705... [Pg.713]

Creput C, Auffret N, Samuel D, Jian R, Hill G, Nochy D. Cutaneous thrombotic microangiopathy during treatment with alpha-interferon for chronic hepatitis C. J Hepatol 2002 37(6) 871-2. [Pg.1827]

Furusyo N, Hayashi J, Ohmiya M, Sawayama Y, Kawakami Y, Ariyama I, Kinukawa N, Kashiwagi S. Differences between interferon-alpha and -beta treatment for patients with chronic hepatitis C virus infection. Dig Dis Sci 1999 44(3) 608-17. [Pg.1837]

Alpha-interferon, a 165 amino acid glycoprotein, is effective in the treatment of viral hepatitis C and B, and also myeloma, melanoma, and renal carcinoma. Little is known about the renal metabolism of alpha-interferon... [Pg.523]

Brooks EA, Lacey LF, Payne SL, Miller DW. Economic evaluation of lamivudine compared with interferon-alpha in the treatment of chronic hepatitis B in the United States. Am J Manag Care 2001 7 677-682. United States Public Health Service. Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV and Recommendations for Postexposure Prophylaxis. MMWR Recomm Rep 2001 50(RR-1 l) l-52. [Pg.758]

Lin CY. Treatment of hepatitis B virus-associated membranous nephropathy with recombinant alpha-interferon. Kidney Int 1995 47 225-230. [Pg.916]

Interferon alfa-2b is an immnnomodnlator. Interferon alfa-2b inhibits virus replication in virns-infected cells and suppresses cell proliferation althongh the exact mechanism of action of ribavirin is not know, it has antiviral inhibitory activity against respiratory syncytial virns, influenza virus, and herpes simplex virus. It is indicated in the treatment of chronic hepatitis C in patients with compensated liver disease previously untreated with alpha interferon or who have relapsed after alpha interferon therapy. [Pg.356]

At present, interferon remains the only accepted treatment for chronic hepatitis B with a success rate of approximately 30-40%, while the major problem with some other drugs include toxicity and lack of antiviral potency (138, 237, 238). Alpha-interferon represents a good compromise since it has both immunomodulatory and antiviral properties. Moreover, it is generally well-tolerated. [Pg.534]

Headache, fever, chills, and muscle aches are common side effects of treatment with interferons. Indications include hepatitis B and C, Kaposi s sarcoma, and human papilloma vims. Lamivudine has adjunctive value when used with interferon alpha in the treatment of hepatitis B. Interferons may also cause neurotoxicity, cardiova.scular dysfunction, and bone marrow depression. The answer is (D). [Pg.438]

A cornerstone of the treatment regimen for chronic hepatitis C infection is an alpha interferon (IFN). IFNs are endogenous glycoproteins produced by a variety of cells, usually in response to a viral infection. The mechanism by which IFN acts against the hepatitis C vims is not completely understood. Possible actions include a direct antiviral effect and to a lesser extent, immune system modulation . Immune system modulation by IFN may be important in that decreases in liver inflammation and fibrosis are considered to be long-term goals in the disease s management. [Pg.60]

Arora A, Vargas L, Kuzniar TJ. Pleural effusion associated with pegylated interferon alpha and ribavirin treatment for chronic hepatitis C. J Hosp Med 2009 4 (7) E45-6. [Pg.605]

Cytokines and biological response modifiers represent a broad class of therapeutic agents that modify the hosts response to cancer or cancer therapies. The enormous body information about their clinical uses and their side effects is beyond the scope of this essay that can only give illustrative examples. For an up-to-date information the reader can resort to reference [5]. As many as 33 different interleukins are known and the list continues to grow IL-2 used in the treatment of kidney cancer is one example. Interferon alpha is used for chronic myelogenous leukeia, hairy cell leukaemia and Kaposi s sarcoma. Interferons are also used in the treatment of chronic infections such as viral hepatitis. Tumor necrosis factor (alpha), G/GM/M-CSF, and several other cellular factors are used in treatment of various cancers. Many of these cytokines produce serious side effects that limit their use. [Pg.268]

Barbaro G, Di Lorenzo G, Soldini M, Giancaspro G, PeUiceUi A, Grisorio B, Barbarini G (1999) Intravenous recombinant interferon-beta versus interferon-alpha-2b and ribavirin in combination for short-term treatment of chronic hepatitis C patients not responding to interferon-alpha. Scand J Gastroenterol 34 928-933... [Pg.230]

CanbakanB, SenturkH, TabakF, Akdogan M, Tahan V, Mert A, Sut N, Ozaras R, Midilli K, Ozbay G (2006) Efficacy of interferon alpha-2b and lamivudine combination treatment in comparison to interferon alpha-2b alone in chronic delta hepatitis a randomized trial. J Gastroenterol Hepatol 21 657-663... [Pg.231]

Flink HJ, van Zonneveld M, Hansen BE, de Man RA, Schalm SW, Janssen HL (2006b) Treatment with Peg-interferon alpha-2b for HBeAg-positive chronic hepatitis B HBsAg loss is associated with HBV genotype. Am J Gastroenterol 101 297-303... [Pg.233]

See other pages where Alpha-interferon hepatitis treatment is mentioned: [Pg.27]    [Pg.234]    [Pg.236]    [Pg.238]    [Pg.240]    [Pg.242]    [Pg.65]    [Pg.688]    [Pg.1824]    [Pg.524]    [Pg.51]    [Pg.530]    [Pg.414]    [Pg.219]    [Pg.6397]    [Pg.606]    [Pg.796]    [Pg.564]    [Pg.238]    [Pg.232]    [Pg.234]    [Pg.235]    [Pg.237]   
See also in sourсe #XX -- [ Pg.1078 ]



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