Type II collagen

Chondronectin May play role in binding type II collagen to surface of cartilage. [Pg.551]

THE MAJOR COMPONENTS OF CARTILAGE ARE TYPE II COLLAGEN CERTAIN PROTEOGLYCANS... [Pg.552]

The principal proteins of hyaline cartilage (the major type of cartilage) are Usted in Table 48—11. Type II collagen is the principal protein (Figure 48—13), and a number of other minor types of collagen are also present. In... [Pg.552]

THE MOLECULAR BASES OF THE CHONDRODYSPLASIAS INCLUDE MUTATIONS IN GENES ENCODING TYPE II COLLAGEN FIBROBLAST GROWTH FACTOR RECEPTORS... [Pg.553]

Hyaluronic acid and collagen are the two main structural components. The collagen is similar to that found in cartilage, consisting of three alpha-chains and known as type II collagen, although subtle differences are now recognized (Swann and Constable, 1972 Swann, 1980). [Pg.133]

Joosten LA, Lubberts E, Helsen MM, et al. Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis. Arthritis Res 1999 1(1) 81—91. [Pg.189]

Min DJ, Cho ML, Lee SH, et al. Augmented production of chemokines by the interaction of type II collagen-reactive T cells with rheumatoid synovial fibroblasts. Arthritis Rheum 2004 50(4) 1146-1155. [Pg.192]

Kasama T, Stricter RM, Lukacs NW, Lincoln PM, Burdick MD, Kunkel SL. Interleukin-10 expression and chemokine regulation during the evolution of murine type II collagen-induced arthritis. J Clin Invest 1995 95(6) 2868-2876. [Pg.198]

Different tissues in the body have different types of collagen (there are 27 in total) classified as collagen types I, II, and so on. Type I collagen, for example, the most abundant collagen of the human body, makes up the tendons and the organic part of bone type II collagen makes up articular cartilage type IV makes up the eye lens type VII and type XI colla-... [Pg.352]

Hollander AP et al (1996) Enhanced denaturation of the alpha (II) chains of type-II collagen in normal adult human intervertebral discs compared with femoral articular cartilage. J Orthop Res 14(l) 61-66... [Pg.226]

Yasuda T, Poole AR (2002) A fibronectin fragment induces type II collagen degradation by collagenase through an interleukin-1-mediated pathway. Arthritis Rheum 46(1) 138—148... [Pg.227]

Yasuda T et al (2006) Peptides of type II collagen can induce the cleavage of type II collagen and aggrecan in articular cartilage. Matrix Biol 25(7) 419-429... [Pg.227]

Stokes DG et al (2001) Regulation of type-II collagen gene expression during human chondrocyte de-differentiation and recovery of chondrocyte-specific phenotype in culture involves Sry-type high-mobility-group box (SOX) transcription factors. Biochem J 360 (Pt 2) 461 170... [Pg.229]

Calderon L et al (2010) Type II collagen-hyaluronan hydrogel-a step towards a scaffold for intervertebral disc tissue engineering. Eur Cell Mater 20 134—148... [Pg.229]

Scheme 13.13 Synthesis of a type II collagen analog using acid-labile carbohydrate...

The synovial arrays were incubated with the sera from patients with early and severe RA as well as healthy patients. Hierarchical clustering analysis revealed that autoreactive B-cell responses for citrullinated epitopes were present in a subset of patients with early RA, features which are predictive of the development of severe RA. In contrast, autoantibodies directed against native epitopes including several human cartilage gp39 peptides and type II collagen, were associated with features predictive of less severe RA. [Pg.207]

Matsumoto N, Iinuma H, Sawa T, Takeuchi T, Hirano S, Yoshioka T, Ishizuka M (1997) Epoxyquinomicins A, B, C and D, New Antibiotics from Amycolatopsis II. Effect on Type II Collagen-Induced Arthritis in Mice. J Antibiot 50 906... [Pg.472]

Type II collagen D-periodic fibril Cartilage, vitreous 338 0... [Pg.305]

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