Intervertebral disc

Taksali, S., Grauer, J.N., and Vaccaro, A.R., Material considerations for intervertebral disc replacement implants. Spine J., 4, 231S-238S, 2004. [Pg.274]

Advances in Tissue Engineering Approaches to Treatment of Intervertebral Disc Degeneration Cells and Polymeric Scaffolds for Nucleus Pulposus Regeneration... [Pg.201]

Abstract Synthetic polymers and biopolymers are extensively used within the field of tissue engineering. Some common examples of these materials include polylactic acid, polyglycolic acid, collagen, elastin, and various forms of polysaccharides. In terms of application, these materials are primarily used in the construction of scaffolds that aid in the local delivery of cells and growth factors, and in many cases fulfill a mechanical role in supporting physiologic loads that would otherwise be supported by a healthy tissue. In this review we will examine the development of scaffolds derived from biopolymers and their use with various cell types in the context of tissue engineering the nucleus pulposus of the intervertebral disc. [Pg.201]

Keywords Biomaterials Biopolymers Intervertebral disc Intervertebral disc degeneration Nucleus pulposus Tissue engineering... [Pg.201]

Table I Summary of the regional differences in the biochemical composition of the intervertebral disc...

T able 2 Summary of the matrix metalloproteinases involved in intervertebral disc degeneration [26,41]... [Pg.207]

An HS, Thonar EJ, Masuda K (2003) Biological repair of intervertebral disc. Spine... [Pg.225]

Masuda K, Lotz JC (2010) New challenges for intervertebral disc treatment using regenerative medicine. Tissue Eng Part B Rev 16(1) 147—158... [Pg.225]

Raj PP (2008) Intervertebral disc anatomy-physiology-pathophysiology-treatment. Pain Pract 8(1) 18 44... [Pg.225]

Roberts S et al (2006) Histology and pathology of the human intervertebral disc. J Bone Joint Surg Am 88(Suppl 2) 10-14... [Pg.226]

Roughley PJ (2004) Biology of intervertebral disc aging and degeneration involvement of the extracellular matrix. Spine 29(23) 2691-2699... [Pg.226]

Eyre DR, Matsui Y, Wu JJ (2002) Collagen polymorphisms of the intervertebral disc. Biochem Soc Trans 30 844-848... [Pg.226]

Urban JP (2000) The nucleus of the intervertebral disc from development to degeneration. Am Zool 40(1) 53-61... [Pg.226]

Le Maitre CL et al (2007) Matrix synthesis and degradation in human intervertebral disc degeneration. Biochem Soc Trans 35(Pt 4) 652-655... [Pg.226]

Richardson SM et al (2007) Intervertebral disc biology, degeneration and novel tissue engineering and regenerative medicine therapies. Histol Histopathol 22(9) 1033-1041... [Pg.226]

Mwale F, Roughley P, Antoniou J (2004) Distinction between the extracellular matrix of the nucleus pulposus and hyaline cartilage a requisite for tissue engineering of intervertebral disc. Eur Cell Mater 8 58-63... [Pg.226]

Homer HA et al (2002) Cells from different regions of the intervertebral disc effect of culture system on matrix expression and cell phenotype. Spine (Phila Pa 1976) 27(10) 1018-1028... [Pg.226]

Roberts S et al (2000) Matrix metalloproteinases and aggrecanase their role in disorders of the human intervertebral disc. Spine (Phila Pa 1976) 25(23) 3005-3013... [Pg.226]

Rutges JP et al (2008) Increased MMP-2 activity during intervertebral disc degeneration is correlated to MMP-14 levels. J Pathol 214(4) 523-530... [Pg.226]

Urban JP, McMullin JF (1988) Swelling pressure of the lumbar intervertebral discs influence of age, spinal level, composition, and degeneration. Spine 13(2) 179-187... [Pg.226]

Wilke HJ et al (1999) New in vivo measurements of pressures in the intervertebral disc in daily life. Spine 24(8) 755-762... [Pg.226]

Boos N et al (2002) Classification of age-related changes in lumbar intervertebral discs 2002 volvo award in basic science. Spine (Phila Pa 1976), 27(23) 2631-2644... [Pg.226]

Roughley PJ et al (2006) The structure and degradation of aggrecan in human intervertebral disc. Eur Spine J 15(Suppl 3) S326-S332... [Pg.226]

Walker MH, Anderson DG (2004) Molecular basis of intervertebral disc degeneration. Spine J 4(6 Suppl) 158S-166S... [Pg.226]

Urban JP, Roberts S (2003) Degeneration of the intervertebral disc. Arthritis Res Ther 5(3) 120-130... [Pg.226]

Antoniou J et al (1996) The human lumbar intervertebral disc evidence for changes in the biosynthesis and denaturation of the extracellular matrix with growth, maturation, ageing, and degeneration. J Clin Invest 98(4) 996-1003... [Pg.226]

Sztrolovics R et al (1997) Aggrecan degradation in human intervertebral disc and articular cartilage. Biochem J 326(Pt 1 ) 235—241... [Pg.226]

Hollander AP et al (1996) Enhanced denaturation of the alpha (II) chains of type-II collagen in normal adult human intervertebral discs compared with femoral articular cartilage. J Orthop Res 14(l) 61-66... [Pg.226]

Goupille P et al (1998) Matrix metalloproteinases the clue to intervertebral disc degeneration Spine (Phila Pa 1976) 23( 14) 1612—1626... [Pg.227]

Le Maitre CL, Freemont AJ, Hoyland JA (2004) Localization of degradative enzymes and their inhibitors in the degenerate human intervertebral disc. J Pathol 204(l) 47-54... [Pg.227]

Zhao CQ et al (2007) The cell biology of intervertebral disc aging and degeneration. Ageing Res Rev 6(3) 247-261... [Pg.227]

Tsantrizos A et al (2005) Internal strains in healthy and degenerated lumbar intervertebral discs. Spine (Phila Pa 1976) 30(19) 2129-2137... [Pg.227]

Chan S, Lam S, Leung V, Chan D, Luk K, Cheung K (2010) Minimizing cryopreservation-induced loss of disc cell activity for storage of whole intervertebral discs. Eur Cells Mater 19 273-283... [Pg.228]

Ganey T et al (2003) Disc chondrocyte transplantation in a canine model a treatment for degenerated or damaged intervertebral disc. Spine (Phila Pa 1976) 28(23) 2609-2620... [Pg.228]

Bae H, Kanim M, Zhao L (2008) Human fetal chondrocyte transplants for damaged intervertebral disc. Spine J 8(5) 928-938... [Pg.228]

Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...