Tumors bronchogenic

Designation of intrathoracic or abdominal tumors as mesotheliomas is not straightforward. A mesothelial mesothelioma may be difficult to distinguish from a peripheral bronchogenic carcinoma partly because of the nature of the clinical course of the diseases as well as their similar location. Mesothelioma spreads extensively on the pleura, is usually unresectable, and responds poorly to chemotherapy or radiation. In all of these respects it is identical to peripheral carcinoma of the lung parenchyma, which may spread to the pleura. The diagnostic distinction, perhaps somewhat academic (Gaenslcr et ah, 1985), must go beyond clinical evaluation to tissue examination. 

It is indicated in GI tract carcinoma, acute myeloblastic leukaemia, bronchogenic, breast and ovarian carcinoma, soft tissue and bone sarcomas, malignant lymphoma primary management of nonmetastatic bladder carcinoma (intravesical administration), Wilm s tumor and neuroblastoma. 

Bronchogenic tumors, human Bronchogenic carcinoma antigen F7... 

In their study of thyroid and pulmonary carcinomas, Kaufmann and DieteP" demonstrated reactivity for surfactant protein A in 3 of 7 thyroid carcinomas in a focal pattern. Byrd-Gloster and coworkers reported that TTF-1 is useful in the distinction of pulmonary small cell carcinomas from Merkel cell carcinomas. In their study, 97% of small cell bronchogenic carcinomas were TTF-1 positive, whereas none of 21 Merkel cell tumors exhibited positivity. However, TTF-1 has been reported in some nonpulmonary small cell carcinomas including those arising in the prostate, urinary bladder, and uterine cervix (see Table 10.6). ... 

Indications—adults leukemias, lymphomas, soft-tissue and bone sarcomas breast, ovarian, transitional cell bladder, thyroid, bronchogenic, and gastric carcinoma children leukemias, lymphomas, Wihns tumor, neuroblastoma, and bone sarcomas. 

K. Usuda, Y. Saito, N. Nagamoto, et al. (1993). Relation between bronchoscopic findings and tumor size of roentgenographically occult bronchogenic squamous cell carcinoma. J. Thorac. Cardiovasc. Surg., 106, 1098-1103. 

The client has developed Cushing s syndrome as a result of an ectopic production of ACTH by a bronchogenic tumor. Which medication would the nurse anticipate the health-care provider prescribing ... 

Smith DR, Polverini PJ, Kunkel SL, et al. Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma. J Exp Med 1994 179 1409-1415. Richmond A, Thomas H. Melanoma growth stimulatory activity isolation from human melanoma tumors and characterization of tissue distribution. J Biol Chem 1988 36 185-198. 

In Phase II clinical trials, emetine as an antineoplastic agent was shown to exert moderate and reversible toxicity, consisting mainly of muscular weakness, local pain, and transient cardiac arrhythmias. However, no complete or partial regression of solid tumors was observed.The studies so far do not appear to indicate that emetine treatment results in tumor response with an acceptable degree of drug related toxicity in epidermoid bronchogenic carcinoma. ... 

Fig. 5.4a-c. A 74-year-old patient with mediastinal spread from bronchogenic carcinoma. The patient complains of superior vena cava obstruction symptoms, a Phlebography of the left upper limb shows narrowing at the confluence of the left innominate vein and the superior vena cava (arrowhead). Moderate reflux of contrast in mediastinal veins, b Phlebography of the right upper limb shows external compression of the superior vena cava by mediastinal tumor below the confluence of the innominate veins (arrow), c Cavography after placement of a Wallstent endoprosthesis (12 mm, 5 cm) demonstrates normal expansion of the superior vena cave at the site of tumor compression... 

Fig. 5.12a, b. A 71-year-old male patient with bronchogenic carcinoma invading the mediastinum and brain metastasis. Superior vena cava obstruction syndrome was treated by placement of a Wallstent endoprosthesis in the superior vena cava. At 3 weeks after endoluminal treatment, obstruction symptoms recurred, a Phlebography obtained by a femoral approach and catheterization of the stent lumen showed stent obstruction, and extensive filling of mediastinal veins, b After balloon dilatation at the junction of the stent with the internal jugular vein, a residual stenosis (arrow), due to insufficient stent covering of mediastinal tumor extent was evident... 

Inhalation of asbestos may causes asbestosis (a pneumonia condition), mesothelioma (a tumor of the mesothelial tissue lining the chest cavity around the lungs), and bronchogenic carcinoma... 

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