Toxicological data

Crospovidone is usually registered as polyvinylpolypyrrolidone or PVPP -in the USA for clarifying beverages and vinegar [488] and in all european and many other countries for stabilizing and clarifying beer and wine. 

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E. Graedel, D. T. Hawkins, and L. D. Cld,si.toQ., Atmospheric Chemical Compounds, Academic Press, Odando, Fla., 1986, p. 263, cited in Hazardous Substances Data Bank, Acetone from Toxicology Data Network (TOXNET), National Library of Medicine, Bethesda, Md., Jan. 1990, NATS section in the review. 

Vinjlidene Fluoride, Toxicology Data, Elf Atochem North America, Inc., Philadelphia, Pa., July 1992. 

Some toxicological data for cyclic ketones are shown in Table 16. Interestingly, toxicity is shown to increase with ring size. This is in reverse order of relative reactivity. 

Table 8. Toxicological Data for Maleic Anhydride, Maleic Acid, and Fumaric Acid ...

Caro s acid is highly corrosive and a powerfiil oxidant. Its acidic properties are similar to those of sulfuric acid of equivalent strength. A strong irritant, it is toxic and should always be handled accordingly. No specific toxicological data are available. 

Stilbene dyes are similar to a2o dyes in their resistance to biological degradation. Typically the BOD is only a small percentage of the COD. Available toxicological data indicate relatively Htde personal or environmental ha2ard (39—42) (Table 4). 

European Commission for these and other substances by nominated dates. The toxicological data and estimation of exposure will form the basis of risk analysis and deterrnination of the appropriate restriction and control of substances in the workplace (58). Restriction of the sales of dangerous substances and preparations to the general pubHc is enforced under Directive 76/769 EC (59). 

P. J. Smith, Toxicological Data on Organotin Compounds, ITRI Pubhcation No. 538, International Tin Research Institute, Petivale, UK, 1977. 

Toxicological data oial, g/kg mixed isomers rat LD50 = >3 45... 

Health and Safety. Littie toxicological data are available on borates other than boric acid and borax. Most water-soluble borates have the same toxicological effects as borax when adjusted to account for differences ia 2 3 content. 

S. W. Souci, Z. Eebensm. Forsch. 108, 189—195 (1958). The Color Committee of the Deutsche Forschungsgemeinschaft. List of Pigments and Dyes for Cosmetics. Toxicological data on dyes and their suitabiUty for food in various countries. 

Cumene, Hazardous Substances Databank No. 172, TOXNET (Toxicology Data Network), National Library of Mediciae, Bethesda, Md., 1989. 

Neady every significant class of dyes and pigments has some members that function as sensitizers. Toxicological data are often included in surveys of dyes (84), reviews of toxic substance identification programs (85), and in material safety data sheets provided by manufacturers of dyes. More specific data about toxicological properties of sensitizing dyes are contained in the Engchpedia under the specific dye classes (see Cyanine dyes Polymethine dyes Xanthene dyes). 

Facility assessment of toxicological data, quantity of material used, and operating conditions indicated plausible conditions exist which could cause serious health effects to nearby receptor. 

Contains the health hazards and risks, toxicological data, and first aid procedures Exposure routes and limits signs and symptoms target organs and medical conditions aggravated by exposure. 

Provides toxicology data for more than 130,000 chemicals in four categories substance identification ... 

Production and Uses of Aliphatic Compounds II Ether, Epoxide and Pnlyeiher, Carboxylic Acids and Their Denvatives, Sulfonic Acids, Toxicological Data of Aliphatic Fluorine Compounds (Ger) Liebig, H, Ulm, K Chem Ztg 100 3-14 270... 

Because secondary alkanesulfonates are used as mixtures of homologs and sulfo group isomers, ecological and toxicological data are presented for these technical products. If not otherwise indicated, the data reported are based on information of two of the major producers [101,102]. 

Actual toxicological data are shown in Table 36 [110,111]. Former results and some specialized data including results of tests on warm-blooded organisms,... 

TABLE 37 Toxicological Data of Homologous Alkanesulfonates (Mouse, Oral Application)... 

On the basis of the available toxicological data and experience, alkane-sulfonates are to be classified and labeled as irritant in accordance with EEC Regulations on Hazardous Substances. 

Information amendments are used to inform the FDA of new pharmacology or toxicology data, final non-dinical study reports, new chemistry-manufacturing-control information, or notice of the discontinuation of a clinical study. 

Table 22 Summary of toxicological data for the critical toxic effects (studies used to derive TDIs in bold type). ...

Based upon the review of the toxicological data, reliable lifetime TDI values for the organotin species in question cannot be derived, since long-term studies at the appropriate doses and in the appropriate species are not available. Medium-term exposure results have therefore been used to derive TDIs for preliminary risk characterization. For dimethyltin, there is a reliable NOAEL as a basis for setting a TDI against a neurotoxicity endpoint. For the remaining compounds, best estimates of amedium-term exposure TDI for preliminary risk characterization have been derived from the available studies (Table 25). 

Table 24 Summary of critical toxicological data in laboratory mammals. ...

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